anti-Human C1R Antikörper für Radial Immunodiffusion

Recommended C1R Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Complement Component 1, R Subcomponent (C1R) Antikörper
  • C1R
  • MGC84776
  • MGC127774
  • c1rl
  • complement component 1, r subcomponent
  • C1R
  • C1r
  • c1r
Reaktivität
Human
74
23
20
4
3
Wirt
Ziege
56
9
7
2
Klonalität
Polyklonal
Konjugat
Dieser C1R Antikörper ist unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunodiffusion (ID), Immunoelectrophoresis (IEP), Radial Immunodiffusion (RID)
47
17
14
13
10
7
6
6
3
3
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN457972
$ 229.09
Zzgl. Versandkosten $45.00

General

Antigen Complement Component 1, R Subcomponent (C1R) Antikörper
Reaktivität Human
(74), (23), (20), (4), (3)
Wirt Ziege
(56), (9), (7), (2)
Klonalität
Polyklonal
Konjugat Dieser C1R Antikörper ist unkonjugiert
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunodiffusion (ID), Immunoelectrophoresis (IEP), Radial Immunodiffusion (RID)
(47), (17), (14), (13), (10), (7), (6), (6), (3), (3), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-C1R Antikörper

Target Details C1R Anwendungsinformationen Handhabung Bilder
Spezifität The antiserum does not cross react with any other component of human plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. of this antiserum has not been tested in detail.
Produktmerkmale Precipitating polyclonal goat antiserum to the C1r subunit of C1 component of human complement
Reinigung Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other plasma proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.
Immunogen C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s. C1r has a molecular weight of 83,000 and is present in plasma in an average concentration of 50 µ g/ml, either as a complex with C1q and C1s or in the absence of C1q as a tetramer with C1s. The subcomponents of the C1 complex are responsible for the initiation of the classical pathway of complement activation. The subunit C1r is isolated as a homogenous protein for use in antiserum production. Freund’s complete adjuvant is used in the first step of the immunization procedure.
Isotyp IgG

Target Details C1R

Produktdetails anti-C1R Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung C1r Subunit of C1 Component of Complement (C1R Antibody Abstract)
Hintergrund The reactivity of the antiserum is restricted to C1r. In immunoelectrophoresis and radial immuno-diffusion (Ouchterlony), using various antiserum concentrations against fresh normal human plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified C1r protein. Complexes containing C1q may also react with the antiserum. No reaction is obtained with C1q, C1s or any other plasma protein component or serum
Pathways Komplementsystem

Anwendungsinformationen

Produktdetails anti-C1R Antikörper Target Details C1R Handhabung Bilder zurück nach oben
Applikationshinweise In precipitating techniques as immunoelectrophoresis and single or double radial immunodiffusion to identify the presence of C1r or C1r containing complexes in human plasma or other body fluids or to determine its concentration. The presence of non precipitating antibodies has not been assayed. This does not exclude the use of the antiserum in more sensitive non-precipitating antibody-binding techniques if proper controls are included.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-C1R Antikörper Target Details C1R Anwendungsinformationen Bilder zurück nach oben
Format Lyophilized
Konzentration IgG protein concentration 11.8 mg/ml. No foreign proteins added. Antibody titre: Precipitin titre 1:16 when tested against in agar-block immunodiffusion titration against appropriate concentrations of purified C1r.
Buffer Delipidated, heat inactivated, lyophilized, stable IgG fraction
Konservierungsmittel Without preservative
Lagerung 4 °C