anti-Hund C1QB Antikörper für Western Blotting

Recommended C1QB Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Complement Component 1, Q Subcomponent, B Chain (C1QB) Antikörper
  • complement component 1, q subcomponent, B chain
  • complement component 1, q subcomponent, beta polypeptide
  • C1QB
  • C1qb
Epitop
Middle Region
18
8
4
4
2
2
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
50
7
7
2
2
1
1
1
1
Wirt
Kaninchen
49
2
Klonalität
Polyklonal
Konjugat
Dieser C1QB Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
48
23
10
8
5
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2781807
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2773842 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 7
1 ABIN469019 WB Rabbit AA 107-156 Anmelden zum Anzeigen Polyclonal

General

Antigen Complement Component 1, Q Subcomponent, B Chain (C1QB) Antikörper
Epitop Middle Region
(18), (8), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
(50), (7), (7), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(49), (2)
Klonalität
Polyklonal
Konjugat Dieser C1QB Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Western Blotting (WB)
(48), (23), (10), (8), (5), (3), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-C1QB Antikörper

Target Details C1QB Anwendungsinformationen Handhabung Referenzen für anti-C1QB Antikörper (ABIN2781807) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974148.
Sequenz PGPKGESGDY KATQKIAFSA TRTINVPLRR DQTIRFDHVI TNMNNNYEPR
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against C1QB. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human C1QB

Target Details C1QB

Produktdetails anti-C1QB Antikörper Anwendungsinformationen Handhabung Referenzen für anti-C1QB Antikörper (ABIN2781807) Bilder zurück nach oben
Antigen
Andere Bezeichnung C1QB (C1QB Antibody Abstract)
Hintergrund C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: IL32, EED, FN1, EDA2R, RELA, MYOC, PTX3, C1R, HRG, DEFA1, C1QC, C1QA,
Protein Size: 253
Molekulargewicht 27 kDa
Gen-ID 713
NCBI Accession NM_000491, NP_000482
UniProt P02746
Forschungsgebiet Neurology, Innate Immunity, Alzheimer's Disease
Pathways Komplementsystem

Anwendungsinformationen

Produktdetails anti-C1QB Antikörper Target Details C1QB Handhabung Referenzen für anti-C1QB Antikörper (ABIN2781807) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 253 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-C1QB Antikörper Target Details C1QB Anwendungsinformationen Referenzen für anti-C1QB Antikörper (ABIN2781807) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-C1QB Antikörper (ABIN2781807)

Produktdetails anti-C1QB Antikörper Target Details C1QB Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Chew, Chua, Lian, Puah, Tan: "PCR-RFLP genotyping of C1q mutations and single nucleotide polymorphisms in Malaysian patients with systemic lupus erythematosus." in: Human biology, Vol. 80, Issue 1, pp. 83-93, 2008

Bilder

Produktdetails anti-C1QB Antikörper Target Details C1QB Anwendungsinformationen Handhabung Referenzen für anti-C1QB Antikörper (ABIN2781807) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (Middle Region) antibody (ABIN2781807) anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (Middle Region) antibody