anti-Hund C1QB Antikörper für Immunohistochemistry

Recommended C1QB Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Complement Component 1, Q Subcomponent, B Chain (C1QB) Antikörper
  • complement component 1, q subcomponent, B chain
  • complement component 1, q subcomponent, beta polypeptide
  • C1QB
  • C1qb
Epitop
C-Term
18
7
4
4
2
2
2
2
2
1
1
1
1
Reaktivität
Hund, Pferd, Human
50
8
8
2
2
2
2
2
1
1
Wirt
Kaninchen
49
2
Klonalität
Polyklonal
Konjugat
Dieser C1QB Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
48
23
9
8
5
3
2
1
1
Optionen
Hersteller
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Produktnummer ABIN2773842
$ 289.00
Zzgl. Versandkosten $45.00

General

Antigen Complement Component 1, Q Subcomponent, B Chain (C1QB) Antikörper
Epitop C-Term
(18), (7), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reaktivität Hund, Pferd, Human
(50), (8), (8), (2), (2), (2), (2), (2), (1), (1)
Wirt Kaninchen
(49), (2)
Klonalität
Polyklonal
Konjugat Dieser C1QB Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(48), (23), (9), (8), (5), (3), (2), (1), (1)
Pubmed 7 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-C1QB Antikörper

Target Details C1QB Anwendungsinformationen Handhabung Referenzen für anti-C1QB Antikörper (ABIN2773842) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN974149.
Sequenz AYNTFQVTTG GMVLKLEQGE NVFLQATDKN SLLGMEGANS IFSGFLLFPD
Homologie Dog: 92%, Horse: 82%, Human: 100%
Produktmerkmale This is a rabbit polyclonal antibody against C1QB. It was validated on Western Blot and immunohistochemistry.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human C1QB

Target Details C1QB

Produktdetails anti-C1QB Antikörper Anwendungsinformationen Handhabung Referenzen für anti-C1QB Antikörper (ABIN2773842) Bilder zurück nach oben
Antigen
Andere Bezeichnung C1QB (C1QB Antibody Abstract)
Hintergrund C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB is the B-chain polypeptide of human complement subcomponent C1q.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.
Alias Symbols: -
Protein Interaction Partner: IL32, EED, FN1, EDA2R, RELA, MYOC, PTX3, C1R, HRG, DEFA1, C1QC, C1QA,
Protein Size: 253
Molekulargewicht 27 kDa
Gen-ID 713
NCBI Accession NM_000491, NP_000482
UniProt P02746
Forschungsgebiet Neurology, Innate Immunity, Alzheimer's Disease
Pathways Komplementsystem

Anwendungsinformationen

Produktdetails anti-C1QB Antikörper Target Details C1QB Handhabung Referenzen für anti-C1QB Antikörper (ABIN2773842) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 253 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-C1QB Antikörper Target Details C1QB Anwendungsinformationen Referenzen für anti-C1QB Antikörper (ABIN2773842) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-C1QB Antikörper (ABIN2773842)

Produktdetails anti-C1QB Antikörper Target Details C1QB Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Takamori, Atsuta, Nakamura, Sawase, Koyano, Hara: "Histopathological comparison of the onset of peri-implantitis and periodontitis in rats." in: Clinical oral implants research, Vol. 28, Issue 2, pp. 163-170, 2016

Noguchi, Ukai, Kuramoto, Yoshinaga, Nakamura, Takamori, Yamashita, Hara: "The histopathological comparison on the destruction of the periodontal tissue between normal junctional epithelium and long junctional epithelium." in: Journal of periodontal research, Vol. 52, Issue 1, pp. 74-82, 2016

Nakatsu, Yoshinaga, Kuramoto, Nagano, Ichimura, Oshino, Yoshimura, Yano, Hara: "Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats." in: Journal of periodontal research, Vol. 49, Issue 3, pp. 314-22, 2014

Nagano, Kaneko, Yoshinaga, Ukai, Kuramoto, Nakatsu, Oshino, Ichimura, Hara: "Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction." in: Journal of periodontal research, Vol. 48, Issue 4, pp. 420-7, 2013

Kuramoto, Yoshinaga, Kaneko, Ukai, Shiraishi, Oshino, Ichimura, Hara: "The formation of immune complexes is involved in the acute phase of periodontal destruction in rats." in: Journal of periodontal research, Vol. 47, Issue 4, pp. 455-62, 2012

Yoshinaga, Ukai, Kaneko, Nakatsu, Shiraishi, Kuramoto, Oshino, Ichimura, Hara: "Topical application of lipopolysaccharide into gingival sulcus promotes periodontal destruction in rats immunized with lipopolysaccharide." in: Journal of periodontal research, Vol. 47, Issue 5, pp. 674-80, 2012

Allgemeine Veröffentlichungen

Roumenina, Ruseva, Zlatarova, Ghai, Kolev, Olova, Gadjeva, Agrawal, Bottazzi, Mantovani, Reid, Kishore, Kojouharova: "Interaction of C1q with IgG1, C-reactive protein and pentraxin 3: mutational studies using recombinant globular head modules of human C1q A, B, and C chains." in: Biochemistry, Vol. 45, Issue 13, pp. 4093-104, 2006

Bilder

Produktdetails anti-C1QB Antikörper Target Details C1QB Anwendungsinformationen Handhabung Referenzen für anti-C1QB Antikörper (ABIN2773842) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibody (ABIN2773842) anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibody