Die folgenden Gennamen und Gensymbole werden für Antigen beta-Site APP-Cleaving Enzyme 2 über verschiedene Spezies hinweg verwendet:

beta-site APP-cleaving enzyme 2 (BACE2), beta-site APP-cleaving enzyme 2 (Bace2), beta-site APP-cleaving enzyme 2 (bace2), beta-site APP-cleaving enzyme 2 (LOC100224177)

Zu den weiteren Synonymen zählen:

ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1, ARP1, AI850424, 1110059C24Rik, bace2, MGC68881, MGC68482, BACE2

Auf Proteinebene tauchen folgende Bezeichner für Antigen beta-Site APP-Cleaving Enzyme 2 auf:

beta-site APP-cleaving enzyme 2 – memapsin-1 – beta secretase 2 – aspartyl protease 1 – 56 kDa aspartic-like protease – Down syndrome region aspartic protease – transmembrane aspartic proteinase Asp1 – membrane-associated aspartic protease 1 – beta-site amyloid beta A4 precursor protein-cleaving enzyme 2 – beta-site APP cleaving enzyme 2 – beta-secretase 2-like

beta-Site APP-Cleaving Enzyme 2 erfüllt eine Reihe von Funktionen:

aspartic-type endopeptidase activity – peptidase activity – hydrolase activity

beta-Site APP-Cleaving Enzyme 2 spielt in den folgenden Prozessen eine Rolle:

membrane protein ectodomain proteolysis – negative regulation of amyloid precursor protein biosynthetic process – peptide hormone processing – protein modification process – protein secretion – proteolysis

beta-Site APP-Cleaving Enzyme 2 ist wie folgt lokalisiert:

Golgi apparatus – integral to membrane – membrane – membrane fraction – endoplasmic reticulum – endosome

Quelle: NCBI Entrez Gene, Gene Ontology