Die folgenden Gennamen und Gensymbole werden für Antigen Jagged 2 über verschiedene Spezies hinweg verwendet:

jagged 2 (JAG2), jagged 2 (Jag2), jagged 2 (jag2)

Zu den weiteren Synonymen zählen:

HJ2, SER2, sm, Serh, D12Ggc2e, mJagged2-1, serB, zgc:152855, JAG2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Jagged 2 auf:

jagged 2 – protein jagged-2 – syndactylism – unp1068 – serrateB – protein jagged-2-like

Jagged 2 erfüllt eine Reihe von Funktionen:

Notch binding – calcium ion binding – growth factor activity – protein binding

Jagged 2 spielt in den folgenden Prozessen eine Rolle:

Notch signaling pathway – auditory receptor cell fate commitment – cell communication – cell cycle – cell differentiation – cell fate determination – gamma-delta T cell differentiation – morphogenesis of embryonic epithelium – multicellular organismal development – odontogenesis of dentine-containing tooth – regulation of apoptosis – regulation of cell adhesion – regulation of cell migration – regulation of cell proliferation – skeletal system development – spermatogenesis – thymic T cell selection – in utero embryonic development – respiratory system process – sensory perception of sound – T cell differentiation – brain development – embryonic limb morphogenesis – male gonad development – regulation of cell differentiation – response to hypoxia – liver development – pancreas development – pronephros development – spinal cord motor neuron differentiation – ventral spinal cord interneuron differentiation

Jagged 2 ist wie folgt lokalisiert:

integral to plasma membrane – membrane – membrane fraction – integral to membrane – perinuclear region of cytoplasm

Quelle: NCBI Entrez Gene, Gene Ontology