Die folgenden Gennamen und Gensymbole werden für Antigen Heart and Neural Crest Derivatives Expressed 2 über verschiedene Spezies hinweg verwendet:

heart and neural crest derivatives expressed 2 (HAND2), heart and neural crest derivatives expressed 2 (Hand2), heart and neural crest derivatives expressed 2 (hand2-A), heart and neural crest derivatives expressed 2 (hand2-b), heart and neural crest derivatives expressed 2 (hand2), heart and neural crest derivatives expressed 2 (LOC100218345)

Zu den weiteren Synonymen zählen:

Hed, dHand, DHAND2, Thing2, bHLHa26, FLJ16260, MGC125303, MGC125304, hand2-A, MGC154423, hand2-b, Hand2', HAND2, dHAND, hed, dhand, dhand2, thing2, xhand2, LOC100218345

Auf Proteinebene tauchen folgende Bezeichner für Antigen Heart and Neural Crest Derivatives Expressed 2 auf:

basic helix-loop-helix transcription factor HAND2 – heart and neural crest derivatives expressed 2 – dHand protein – heart and neural crest derivatives expressed transcript 2 – heart- and neural crest derivatives-expressed protein 2

Heart and Neural Crest Derivatives Expressed 2 erfüllt eine Reihe von Funktionen:

DNA binding – promoter binding – protein heterodimerization activity – protein homodimerization activity – transcription activator binding – transcription coactivator activity – transcription factor binding – protein binding – protein domain specific binding – transcription activator activity – transcription factor activity – transcription regulator activity

Heart and Neural Crest Derivatives Expressed 2 spielt in den folgenden Prozessen eine Rolle:

adult heart development – angiogenesis – apoptosis – cell differentiation – heart looping – in utero embryonic development – multicellular organismal development – neural crest cell development – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – heart development – heart morphogenesis – regulation of transcription

Heart and Neural Crest Derivatives Expressed 2 ist wie folgt lokalisiert:

nucleus – transcription factor complex

Quelle: NCBI Entrez Gene, Gene Ontology