Die folgenden Gennamen und Gensymbole werden für Antigen E1A Binding Protein P300 über verschiedene Spezies hinweg verwendet:

E1A binding protein p300 (EP300), E1A binding protein p300 (Ep300), E1A-associated protein p300 (EP300), E1A binding protein p300 (ep300)

Zu den weiteren Synonymen zählen:

p300, KAT3B, EP300

Auf Proteinebene tauchen folgende Bezeichner für Antigen E1A Binding Protein P300 auf:

E1A binding protein p300 – E1A-binding protein, 300kD – E1A-associated protein p300 – histone acetyltransferase p300 – histone acetyltransferase – histone acetyltransferase p300-like

E1A Binding Protein P300 erfüllt eine Reihe von Funktionen:

acetyltransferase activity – histone acetyltransferase activity – metal ion binding – peroxisome proliferator activated receptor binding – protein C-terminus binding – transcription coactivator activity – transcription factor activity – transferase activity – zinc ion binding – DNA binding – NF-kappaB binding – SMAD binding – antigen binding – bHLH transcription factor binding – glucocorticoid receptor binding – lysine N-acetyltransferase activity – mitogen-activated protein kinase binding – promoter binding – protein binding – protein complex binding – protein kinase binding – transcription activator activity – transcription factor binding

E1A Binding Protein P300 spielt in den folgenden Prozessen eine Rolle:

N-terminal peptidyl-lysine acetylation – apoptosis – cell cycle – heart development – histone acetylation – homeostatic process – interspecies interaction between organisms – lung development – nervous system development – organ morphogenesis – positive regulation of transcription factor activity – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – response to hypoxia – signal transduction – skeletal muscle tissue development – somitogenesis – cellular response to hydrogen peroxide – gut development – liver development – negative regulation of cellular metabolic process – positive regulation of DNA binding – positive regulation of axon extension – positive regulation of cell growth – positive regulation of cell size – positive regulation of cellular metabolic process – positive regulation of collagen biosynthetic process – positive regulation of gene expression – positive regulation of glycoprotein biosynthetic process – positive regulation of protein amino acid phosphorylation – positive regulation of protein import into nucleus, translocation – positive regulation of protein secretion – positive regulation of proteolysis – positive regulation of sarcomere organization – positive regulation of transcription, DNA-dependent – positive regulation of translation – protein kinase B signaling cascade – protein-DNA complex assembly – regulation of angiotensin metabolic process – regulation of transcription – response to calcium ion – response to cobalt ion – response to drug – response to estrogen stimulus – response to ethanol – response to fatty acid – response to glucocorticoid stimulus – response to glucose stimulus – response to hydrogen peroxide – response to organic cyclic substance – response to protein stimulus – response to retinoic acid

E1A Binding Protein P300 ist wie folgt lokalisiert:

cytoplasm – histone acetyltransferase complex – nucleolus – nucleus – transcription factor complex

Quelle: NCBI Entrez Gene, Gene Ontology