Produkt verwendet in:
Sporková, Kopkan, Varcabová, Husková, Hwang, Hammock, Imig, Kramer, Cervenka: "Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 300, Issue 6, pp. R1468-75, 2011 (PubMed).
Xu, Zhao, Wang, Tu, Fang, Zheng, Edin, Zeldin, Wang: "Increased CYP2J3 expression reduces insulin resistance in fructose-treated rats and db/db mice." in: Diabetes, Vol. 59, Issue 4, pp. 997-1005, 2010 (PubMed).
Zheng, Wang, Li, Ma, Tu, Xu, Dackor, Zeldin, Wang: "Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats." in: American journal of respiratory cell and molecular biology, Vol. 43, Issue 6, pp. 740-9, 2010 (PubMed).
Xiao, Li, Yan, Yu, Yang, Xiao, Voltz, Zeldin, Wang: "Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide." in: The Journal of pharmacology and experimental therapeutics, Vol. 334, Issue 3, pp. 784-94, 2010 (PubMed).
Merkel, Liu, Cao, Packwood, Young, Alkayed, Van Winkle: "Inhibition of soluble epoxide hydrolase preserves cardiomyocytes: role of STAT3 signaling." in: American journal of physiology. Heart and circulatory physiology, Vol. 298, Issue 2, pp. H679-87, 2010 (PubMed).
Certíková Chábová, Walkowska, Kompanowska-Jezierska, Sadowski, Kujal, Vernerová, Vanourková, Kopkan, Kramer, Falck, Imig, Hammock, Vanecková, Cervenka: "Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats." in: Clinical science (London, England : 1979), Vol. 118, Issue 10, pp. 617-32, 2010 (PubMed).
Chen, Li, Liao, Wu, Liu, Ma, Zhou, Elbekai, Edin, Zeldin, Wang: "Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo." in: The Journal of pharmacology and experimental therapeutics, Vol. 329, Issue 3, pp. 908-18, 2009 (PubMed).
Zhang, Iliff, Campbell, Wang, Hurn, Alkayed: "Role of soluble epoxide hydrolase in the sex-specific vascular response to cerebral ischemia." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 29, Issue 8, pp. 1475-81, 2009 (PubMed).
Eldrup, Soleymanzadeh, Taylor, Muegge, Farrow, Joseph, McKellop, Man, Kukulka, De Lombaert: "Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase." in: Journal of medicinal chemistry, Vol. 52, Issue 19, pp. 5880-95, 2009 (PubMed).
Zhang, Otsuka, Sugo, Ardeshiri, Alhadid, Iliff, DeBarber, Koop, Alkayed: "Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia." in: Stroke; a journal of cerebral circulation, Vol. 39, Issue 7, pp. 2073-8, 2008 (PubMed).
Koerner, Jacks, DeBarber, Koop, Mao, Grant, Alkayed: "Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 17, pp. 4642-9, 2007 (PubMed).
Jiang, Ning, Chen, Ma, Liu, Yang, Zhou, Xiao, Zhang, Edin, Card, Wang, Zeldin, Wang: "Cytochrome p450 epoxygenase promotes human cancer metastasis." in: Cancer research, Vol. 67, Issue 14, pp. 6665-74, 2007 (PubMed).
Yang, Lin, Chen, Lee, Seubert, Wang, Wang, Chao, Tao, Gong, Lu, Wang, Zeldin: "Cytochrome P-450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-alpha via MAPK and PI3K/Akt signaling pathways." in: American journal of physiology. Heart and circulatory physiology, Vol. 293, Issue 1, pp. H142-51, 2007 (PubMed).
Liu, Li, Chao, Wu, Lin, Tsai, Chen: "Synergistic effect of cytochrome P450 epoxygenase CYP2J2*7 polymorphism with smoking on the onset of premature myocardial infarction." in: Atherosclerosis, Vol. 195, Issue 1, pp. 199-206, 2007 (PubMed).
Jiang, Chen, Card, Yang, Chen, Fu, Ning, Xiao, Zeldin, Wang: "Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors." in: Cancer research, Vol. 65, Issue 11, pp. 4707-15, 2005 (PubMed).
Spiecker, Darius, Hankeln, Soufi, Sattler, Schaefer, Node, Börgel, Mügge, Lindpaintner, Huesing, Maisch, Zeldin, Liao: "Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2." in: Circulation, Vol. 110, Issue 15, pp. 2132-6, 2004 (PubMed).