Anti-Cytomegalovirus IgG Antibody ELISA Kit

Antigen: Anti-Cytomegalovirus IgG Antibody

Applikation: ELISA

Produktnummer: ABIN459322

Produktbeschreibung

Produktmerkmale: anti-CMV IgG-ELISA kit for the detection of IgG antibodies to human cytomegalovirus (CMV). The test is intended for the diagnosis of CMV-caused or CMV-associated diseases such as infectious mononucleosis (IM), CMV syndrome, acute and chronic active CMV infection in immunocompromised patients. The kit could be used for a complex characterisation of chronic fatigue syndrom and to test CMV seropositivity of blood and organ transplantation donors and acceptors.

Weitere Bezeichnung: anti-Cytomegalovirus (CMV) IgG antibodies

Sensitivität: Diagnostic sensitivity of the test is 99,8%. Diagnostic sensitivity was determined by a multicentric evaluation study of this test. 5 Serum samples of 544 CMV-IgG negative and 1101 CMV-IgG positive people were tested by the kit and the results were confirmed by other commercially available diagnostic tests. Diagnostic specificity is 100%.

Anwendungen

Prinzip: ELISA-VIDITEST anti-CMV IgG is a solid-phase immunoanalytical test. The strips are coated by a mixture of specific antigens that bear immunodominant CMV epitopes. The anti-CMV antibodies, if present in the tested sera, bind to the immobilized antigens. The antibodies being in complexes with antigen are later on recognised by animal anti-human IgG antibodies labelled with horseradish peroxidase. The labelled antibodies are revealed by an enzymatic reaction with a chromogenic substrate. Negative sera do not react and the mild change in colour, if present, may be attributed to the reaction background.

Beschränkungen: Nur für Forschungszwecke einsetzbar