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IL12 ELISA Kit

IL12 Reaktivität: Human Colorimetric Sandwich ELISA Cell Culture Supernatant, Plasma, Serum
Produktnummer ABIN2690562
  • Target Alle IL12 ELISA Kits anzeigen
    IL12 (Interleukin 12 (IL12))
    Reaktivität
    • 15
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Nachweismethode
    Colorimetric
    Methodentyp
    Sandwich ELISA
    Applikation
    ELISA
    Verwendungszweck
    The Human IL-12 (p40) ELISA Kit II is for the quantitative determination of human IL-12 (p40) in serum, plasma, and cell culture supernatant.
    Marke
    BD OptEIA™
    Proben
    Serum, Plasma, Cell Culture Supernatant
    Analytische Methode
    Quantitative
    Featured
    Zu unserem meistverkauften IL12 ELISA Kit
    Top Product
    Discover our top product IL12 ELISA Kit
  • Applikationshinweise
    The ELISA Kit II format was developed for superior accuracy with serum and plasma specimens. The data that demonstrates this enhancement can be located in the Performance "Recovery" and "Linearity" sections.
    Kommentare

    BD OptEIA™ Human IL-12 (p40) ELISA Kit II

    Plattentyp
    Pre-coated
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C
    Informationen zur Lagerung
    1. Store unopened kit at 2 - 8°C. Do not use kit after expiration date.
    2. Before use, bring all reagents to room temperature (18 - 25°C). Immediately after use, return to proper storage conditions.
    3. Lyophilized standards are stable until kit expiration date. After reconstitution, use freshly reconstituted standard within 12 hours (stored at 2 - 8°C).
  • Ling, Gately, Gubler, Stern, Lin, Hollfelder, Su, Pan, Hakimi: "Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 1, pp. 116-27, (1995) (PubMed).

    DAndrea, Rengaraju, Valiante, Chehimi, Kubin, Aste, Chan, Kobayashi, Young, Nickbarg: "Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells." in: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1387-98, (1992) (PubMed).

  • Target Alle IL12 ELISA Kits anzeigen
    IL12 (Interleukin 12 (IL12))
    Andere Bezeichnung
    IL-12 (IL12 Produkte)
    Synonyme
    CLMF ELISA Kit, CLMF2 ELISA Kit, IL-12B ELISA Kit, NKSF ELISA Kit, NKSF2 ELISA Kit, p40 ELISA Kit, Il-12b ELISA Kit, Il12p40 ELISA Kit, Il-12p40 ELISA Kit, Il12 ELISA Kit, IL-12p40 ELISA Kit, IL-12 ELISA Kit, LOC100217488 ELISA Kit, IL-12p35 ELISA Kit, Il-12a ELISA Kit, Ll12a ELISA Kit, p35 ELISA Kit, IL12p40 ELISA Kit, IL12B ELISA Kit, IL-12 p35 ELISA Kit, interleukin 12B ELISA Kit, interleukin 12A ELISA Kit, interleukin 12b ELISA Kit, interleukin 12a ELISA Kit, Interleukin 12 level ELISA Kit, IL12B ELISA Kit, IL12A ELISA Kit, Il12b ELISA Kit, Il12a ELISA Kit, IL12 ELISA Kit, il12a ELISA Kit
    Hintergrund
    Interleukin 12 (IL-12) is a potent regulator of cell-mediated immune responses. Biologically active IL-12 is secreted by activated B lymphocytes and macrophages as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD (p35)and 40 kD (p40) subunits. The IL-12 p40 monomer shares amino acid sequence homology with the IL-6 receptor. It has been reported that activated PBMCs producea manyfold excess of IL-12 p40 monomer over the bioactive p70 heterodimer.The IL-12 p40 monomer has been reported to inhibit binding of IL-12 p70 to the IL-12 receptor, but with 20x less effectiveness than the IL-12 p70 homodimer.
    Pathways
    JAK-STAT Signalweg, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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