anti-Thrombopoietin (THPO) Antikörper

Bezeichnung:
anti-Thrombopoietin Antikörper (THPO)
Auf www.antikoerper-online.de finden Sie aktuell 175 Thrombopoietin (THPO) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Thrombopoietin Proteine (73) und Thrombopoietin Kits (72) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 335 Thrombopoietin Produkte verfügbar.
Synonyme:
LOC100231762, Mgdf, MKCSF, Ml, Mpllg, THCYT1, Tpo, Tpo1, Tpo2, Tpo3, Tpo4

Meistgesuchte Reaktivitäten zu anti-Thrombopoietin (THPO) Antikörper

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anti-Human Thrombopoietin Antikörper:

anti-Mouse (Murine) Thrombopoietin Antikörper:

anti-Rat (Rattus) Thrombopoietin Antikörper:

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Am meisten referenzierte anti-Thrombopoietin Antikörper

  1. Human Polyclonal Thrombopoietin Primary Antibody für EIA, WB - ABIN359714 : Baker, Su, Hsu, Shi, Zhao, Strande, Fu, Xu, Eis, Komorowski, Jensen, Tweddell, Rafiee, Gross: Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats. in Cardiovascular research 2008 (PubMed)
    Zeige alle 3 Referenzen für 359714

  2. Human Monoclonal Thrombopoietin Primary Antibody für FACS, ELISA - ABIN969571 : Graziano, Carone, Panza, Marino, Magini, Romeo, Pession, Seri: Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation. in Blood 2009 (PubMed)
    Zeige alle 2 Referenzen für 969571

  3. Human Monoclonal Thrombopoietin Primary Antibody für EIA, WB - ABIN1109245 : Eissa, Gad, Rabie, El-Gayar: Thrombopoietin level in patients with chronic liver diseases. in Annals of hepatology 2008 (PubMed)
    Zeige alle 2 Referenzen für 1109245

  4. Dog (Canine) Polyclonal Thrombopoietin Primary Antibody für WB - ABIN2787808 : Baker, Gray, Wright, Fitzsimons, Nimmo, Lowry, Mutrie,: The effect of a pedometer-based community walking intervention "Walking for Wellbeing in the West" on physical activity levels and health outcomes: a 12-week randomized controlled trial. in The international journal of behavioral nutrition and physical activity 2008 (PubMed)
    Zeige alle 2 Referenzen für 2787808

  5. Human Polyclonal Thrombopoietin Primary Antibody für EIA, Func - ABIN116255 : Xie, Chan, Johnson, Starr, McCarthy, Kapur, Yoder: Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs. in Blood 2003 (PubMed)

  6. Human Polyclonal Thrombopoietin Primary Antibody für WB - ABIN391802 : Kanayasu-Toyoda, Ishii-Watabe, Suzuki, Oshizawa, Yamaguchi: A new role of thrombopoietin enhancing ex vivo expansion of endothelial precursor cells derived from AC133-positive cells. in The Journal of biological chemistry 2007 (PubMed)

  7. Human Polyclonal Thrombopoietin Primary Antibody für IF (p), IHC (p) - ABIN1714401 : Nakamura-Ishizu, Takubo, Kobayashi, Suzuki-Inoue, Suda: CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow. in The Journal of experimental medicine 2015 (PubMed)

Weitere Antikörper gegen Thrombopoietin Interaktionspartner

Zebrafish Thrombopoietin (THPO) Interaktionspartner

  1. These studies indicate that the functional role of Tpo in the differentiation of thrombocytes from hematopoietic stem and progenitor cells is well conserved among vertebrate organisms, positing the zebrafish as an excellent model to investigate diseases caused by dysregulated erythro- and thrombo-poietic differentiation.

Human Thrombopoietin (THPO) Interaktionspartner

  1. Genetically engineered mesenchymal stromal cells produce IL-3 (zeige IL-3 Antikörper) and TPO to further improve human scaffold-based xenograft models

  2. bone marrow megakaryocytes possess a complete mechanism to synthesize the ECM (zeige MMRN1 Antikörper) components, and that thrombopoietin is a pivotal regulator of this new function inducing transforming growth factor-b1 (TGF-beta1 (zeige TGFB1 Antikörper)) release and consequent activation of the downstream pathways, both in vitro and in vivo

  3. High Thrombopoietin expression is associated with immune thrombocytopenia in pregnancy.

  4. Colorectal cancer tumor-initiating cells (TICs) expressing CD110 (zeige MPL Antikörper), the thrombopoietin (TPO)-binding receptor, mediate liver metastasis. We show that TPO promotes metastasis of CD110 (zeige MPL Antikörper)+ TICs to the liver by activating lysine degradation.

  5. decreased TPO levels or decreased bone marrow production of platelets may not be a cause of thrombocytopenia in chronic hepatitis C

  6. WASP (zeige WASL Antikörper), RUNX1 (zeige RUNX1 Antikörper), and ANKRD26 (zeige ANKRD26 Antikörper) genes are important for normal TPO signaling and the network underlying thrombopoiesis.

  7. Data suggest that elevated serum level of thrombopoietin may serve as unfavorable marker of stage of multiple myeloma.

  8. The regulation of OCs by TPO highlights a novel therapeutic target for bone loss diseases and may be important to consider in the numerous hematologic disorders associated with alterations in TPO/c-mpl (zeige MPL Antikörper) signaling

  9. TPO was greatly enhanced in HPT in comparison with ITP (zeige ITPA Antikörper) patients (958 +/- 659 and 11 +/- 27 pg/ml, p < 0.001). In the ITP (zeige ITPA Antikörper) group a reverse correlation was detected between TPO and glycocalicin (r = -0.373, p = 0.006).

  10. observations suggest that NRP-1 (zeige NELL1 Antikörper) is involved in megakaryocytopoiesis through complex formation with PDGFRs, and that NRP-1 (zeige NELL1 Antikörper)-PDGFR (zeige PDGFRB Antikörper)-complexes may contribute to effective cellular functions mediated by TPO and PDGF (zeige PDGFA Antikörper) in megakaryocytic cells

Cow (Bovine) Thrombopoietin (THPO) Interaktionspartner

  1. The results demonstrate the possible involvement of locally produced TPO (zeige TPO Antikörper)/c-MPL (zeige MPL Antikörper) system as a 'physiological filter' in bovine ovary where they may promote cell selection by inducing proliferation of viable cells and scavenging non-viable cells.

Mouse (Murine) Thrombopoietin (THPO) Interaktionspartner

  1. Thrombopoietin-mediated phosphorylation of STAT5 (zeige STAT5A Antikörper) triggers its genome-wide relocation to STAT (zeige STAT1 Antikörper) consensus sites, resulting in loss of a uSTAT5 program that restrains megakaryocytic differentiation and activation of STAT5 (zeige STAT5A Antikörper)-driven gene expression.

  2. Furthermore, although the contribution of the TPO treated graft to long-term hematological engraftment was reduced, the TPO treated and untreated grafts both contributed significantly to long-term chimerism in vivo.

  3. TPO treatment also promoted the peripheral induction of Foxp3 (zeige FOXP3 Antikörper)(+) Tregs in conjunction with elevated circulating TGF-beta (zeige TGFB1 Antikörper) levels.

  4. novel findings about aspects of TPO action on stem cells

  5. Mpl (zeige MPL Antikörper) expression, but not Tpo, is fundamental in the development of JAK2V617F(+) myeloproliferative neoplasms

  6. Thrombopoietin/MPL (zeige MPL Antikörper) signaling confers growth and survival capacity to CD41-positive cells in a mouse model of Evi1 (zeige MECOM Antikörper) leukemia.

  7. Megakaryocytes regulate cell cycle quiescence of hematopoietic stem cell through the production of thrombopoietin.

  8. IEX-1 (zeige IER3 Antikörper) has a role in activation of Erk (zeige EPHB2 Antikörper) and NF-kB pathways, which affects thrombopoietin-promoted NHEJ DNA repair in hematopoietic stem cells

  9. Findings establish that Clock regulates Thpo and Mpl (zeige MPL Antikörper) expression in vivo, and demonstrate an important link between the body's circadian timing mechanisms and megakaryopoiesis.

  10. Signal transduction pathway of ERK1/2 (zeige MAPK1/3 Antikörper) participates in the activation of thrombopoietin in inflammatory injury of BV2 (zeige DNAH9 Antikörper) cells.

Thrombopoietin (THPO) Antigen-Profil

Beschreibung des Gens

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.

Alternative names and synonyms associated with Thrombopoietin (THPO)

  • thrombopoietin (THPO) Antikörper
  • thrombopoietin (thpo) Antikörper
  • thrombopoietin (LOC100231762) Antikörper
  • thrombopoietin (Thpo) Antikörper
  • thrombopoietin-like (LOC100620258) Antikörper
  • thrombopoietin-like (LOC100357079) Antikörper
  • thrombopoietin-like (LOC100855822) Antikörper
  • LOC100231762 Antikörper
  • Mgdf Antikörper
  • MKCSF Antikörper
  • Ml Antikörper
  • Mpllg Antikörper
  • THCYT1 Antikörper
  • Tpo Antikörper
  • Tpo1 Antikörper
  • Tpo2 Antikörper
  • Tpo3 Antikörper
  • Tpo4 Antikörper

Bezeichner auf Proteinebene für anti-Thrombopoietin (THPO) Antikörper

thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) , thrombopoietin , MPL ligand , c-mpl ligand , megakaryocyte colony-stimulating factor , megakaryocyte growth and development factor , megakaryocyte stimulating factor , myeloproliferative leukemia virus oncogene ligand , thrombopoietin nirs variant 1 , C-mpl ligand

GENE ID SPEZIES
736549 Pan troglodytes
100189608 Danio rerio
100231762 Taeniopygia guttata
100302539 Felis catus
100582097 Nomascus leucogenys
7066 Homo sapiens
538672 Bos taurus
21832 Mus musculus
81811 Rattus norvegicus
414803 Gallus gallus
607489 Canis lupus familiaris
100726592 Cavia porcellus
101119601 Ovis aries
100620258 Sus scrofa
100357079 Oryctolagus cuniculus
100855822 Canis lupus familiaris
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