STAT6 Proteine (STAT6)

Bezeichnung:
Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced Proteine (STAT6)
Auf www.antikoerper-online.de finden Sie aktuell 15 Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen STAT6 Antikörper (453) und STAT6 Kits (44) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 528 STAT6 Produkte verfügbar.
Synonyme:
D12S1644, IL-4-STAT, STAT6B, STAT6C
alle Proteine anzeigen Gen GeneID UniProt
STAT6 20852 P52633
STAT6 6778 P42226
STAT6 362896  

Weitere Synonyme anzeigen

STAT6 Proteine (STAT6) nach Spezies

Wählen Sie die gewünschte Spezies

Am meisten referenzierte STAT6 Proteine

  1. Human STAT6 Protein expressed in Baculovirus infected Insect Cells - ABIN2005539 : Litterst, Pfitzner: Transcriptional activation by STAT6 requires the direct interaction with NCoA-1. in The Journal of biological chemistry 2001 (PubMed)
    Zeige alle 2 Referenzen für 2005539

Weitere Proteine zu STAT6 Interaktionspartnern

Mouse (Murine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Interaktionspartner

  1. These data indicate a role for STAT3 (zeige STAT3 Proteine) in maintaining a steady state in the beta-cell, by modulating its cell cycle and protection from DNA damage.

  2. STAT6 phosphorylation (p-STAT6) was significantly increased in TECs from both Grave's disease patients and experimental autoimmune Graves' disease mice.

  3. this study shows that sodium benzoate induces the expression of TGF-beta (zeige TGFB1 Proteine) in splenocytes and alleviates experimental allergic encephalomyelitis via the STAT6-TGF-beta (zeige TGFB1 Proteine)-Treg pathway

  4. this study shows that wild-type mice develop an eosinophilic Th2 airway disease in response to Alternaria alternata exposure, whereas STAT6-deficient mice exhibit a primarily neutrophilic response

  5. this study shows that IL-17A (zeige IL17A Proteine) contributes to asthma pathophysiology by increasing the capacity of IL-13 (zeige IL13 Proteine) to activate intracellular signaling pathways, such as STAT6 activation

  6. RCM-1 (zeige TNNI3 Proteine) reduced IL-13 (zeige IL13 Proteine) and STAT6 (signal transducer and activator of transcription 6) signaling and prevented the expression of the STAT6 target genes Spdef and Foxa3 (zeige FOXA3 Proteine), which are key transcriptional regulators of goblet cell differentiation.

  7. These studies are the first to demonstrate that gammadelta17 cells express the type I IL-4 (zeige IL4 Proteine) receptor and that STAT6 signaling negatively regulates gammadelta17 cells, a cell population that plays a front-line role in mucosal immunity.

  8. this study identifies proteins in B cells that are regulated by IL-4 in a STAT6-dependent manner, which may contribute to germinal center formation and IgE switching in type 2 immunity

  9. Study showed that suppression of STAT3 (zeige STAT3 Proteine), STAT5 (zeige STAT5A Proteine), and STAT6 and overexpression of the proapoptotic factor STAT1 (zeige STAT1 Proteine), which provides p53 (zeige TP53 Proteine)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (zeige ERBB2 Proteine) tyrosine kinase receptor (zeige KDR Proteine) overexpression promotes neuronal survival through activation of STAT (zeige STAT1 Proteine)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (zeige STAT1 Proteine)

  10. STAT6 mediates the CT-induced TIM4 (zeige TIMD4 Proteine) expression in DCs. In conclusion, p300 (zeige NOTCH1 Proteine) and STAT6 mediate the microbial product CT-induced TIM4 (zeige TIMD4 Proteine) expression in DCs.

Human Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Interaktionspartner

  1. The results suggest that nuclear localization and cleavage of STAT6 is important for modulating the viral latency and pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV).

  2. the phosphorylation of signal transducer and activator of transcription 1 (STAT1 (zeige STAT1 Proteine)-py) was impaired in asthmatics, whereas the phosphorylation of signal transducer and activator of transcription 6 (STAT6-py) was slightly enhanced.

  3. PVT1-derived miR (zeige MLXIP Proteine)-1207-5p promotes the proliferation of breast cancer cells by targeting STAT6.

  4. STAT6 single-nucleotide polymorphism is associated with migraine.

  5. STAT6 phosphorylation (p-STAT6) was significantly increased in TECs from both Grave's disease patients and experimental autoimmune Graves' disease mice.

  6. Here, we demonstrate that pulmonary adenofibromas are neoplastic lesions harbouring NAB2 (zeige NAB2 Proteine)-STAT6 fusion genes ,the molecular hallmark of solitary fibrous tumours.

  7. STAT6 and ALDH1 (zeige ALDH1A1 PLURAL_@39934@) immunohistochemistry can be used in the differential diagnosis of solitary fibrous tumor versus prostate-specific (zeige KLK3 PLURAL_@39934@) stromal neoplasms.

  8. Our results represented that meningeal solitary fibrous tumor/hemangiopericytoma were in a single biological spectrum with NAB2 (zeige NAB2 Proteine)-STAT6 gene fusion as was nonmeningeal solitary fibrous tumor

  9. STAT6-TMEM16A (zeige ANO1 Proteine)-ERK1/2 signal pathway and TMEM16A (zeige ANO1 Proteine) channel activity are required for the IL-13 (zeige IL13 Proteine)-induced TMEM16A (zeige ANO1 Proteine) mediated mucus production

  10. The detection of nuclear relocation of STAT6 with immunohistochemistry is a characteristic of solitary fibrous tumours (SFTs), and may serve as a diagnostic marker that indicates NAB2 (zeige NAB2 Proteine)-STAT6 fusion and helps to discriminate SFTs from histological mimics.

Pig (Porcine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Interaktionspartner

  1. this study shows that weaning caused severe inflammation associated with the suppression of STAT6 in the jejunum of piglets

  2. Data show that IL-4 (zeige IL4 Proteine) induces upregulation of the junction protein claudin-5 (zeige CLDN5 Proteine) in endothelial cells (ECs) through activation of Jak (zeige JAK3 Proteine)/STAT6 and phosphorylation and translocation of FoxO1 (zeige FOXO1 Proteine) from the nucleus to the cytoplasm.

Cow (Bovine) Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Interaktionspartner

  1. Results provide evidence that polymorphisms in STAT6 are associated with carcass and growth efficiency traits

Guinea Pig Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) Interaktionspartner

  1. IL-4 (zeige IL4 Proteine) and STAT6 are related to the pathogenesis of allergic rhinitis and may be the main factors for eosinophil infiltration in allergic rhinitis.

STAT6 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with STAT6

  • signal transducer and activator of transcription 6, interleukin-4 induced (STAT6)
  • signal transducer and activator of transcription 6 (Stat6)
  • signal transducer and activator of transcription 6-like (LOC100859543)
  • signal transducer and activator of transcription 6, interleukin-4 induced (Stat6)
  • D12S1644 Protein
  • IL-4-STAT Protein
  • STAT6B Protein
  • STAT6C Protein

Bezeichner auf Proteinebene für STAT6

signal transducer and transcription activator 6 , STAT, interleukin4-induced , signal transducer and activator of transcription 6 , transcription factor IL-4 STAT

GENE ID SPEZIES
100050053 Equus caballus
20852 Mus musculus
100859543 Gallus gallus
6778 Homo sapiens
100142679 Canis lupus familiaris
362896 Rattus norvegicus
100153518 Sus scrofa
353105 Bos taurus
100344264 Oryctolagus cuniculus
100726686 Cavia porcellus
Ausgewählte Anbieter für STAT6 Proteine (STAT6)
Haben Sie etwas anderes gesucht?