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STAT5B Proteine (STAT5B)

Bezeichnung:
Signal Transducer and Activator of Transcription 5B Proteine (STAT5B)
Auf www.antikoerper-online.de finden Sie aktuell 11 Signal Transducer and Activator of Transcription 5B (STAT5B) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen STAT5B Antikörper (202) und STAT5B Kits (28) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 257 STAT5B Produkte verfügbar.
Synonyme:
STAT5, STAT5A, stat5b
alle Proteine anzeigen Gen GeneID UniProt
STAT5B 6777 P51692
STAT5B 20851 P42232
STAT5B 25126 P52632

Weitere Synonyme anzeigen

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Weitere Proteine zu STAT5B Interaktionspartnern

Zebrafish Signal Transducer and Activator of Transcription 5B (STAT5B) Interaktionspartner

  1. This study indicates that CISH (zeige CISH Proteine) functions as a conserved in vivo target and regulator of STAT5 in the control of embryonic hematopoiesis.

  2. study demonstrates that STAT5 in basophils is activated through both the IL-3 (zeige IL-3 Proteine) and the FcepsilonRI (zeige FCER1G Proteine) signaling pathway

  3. Studies demonstrate a conserved role for SOCS1 (zeige SOCS1 Proteine) in T cell development and suggest a novel T cell-independent function in embryonic myelopoiesis mediated, at least in part, via its effects on receptors using the Jak2 (zeige JAK2 Proteine)-Stat5 pathway.

  4. The stat5.1 gene lies next to the stat3 (zeige STAT3 Proteine) gene.

Human Signal Transducer and Activator of Transcription 5B (STAT5B) Interaktionspartner

  1. Data show that signal transducer and activator of transcription 5 STAT5A (zeige STAT5A Proteine) and STAT5B have distinctive and potentially important roles in regulation of hepatic drug response genes as well as in contributing to gender-related differences in expression of hepatic cytochrome P450s (CYPs) and transcription factors (TFs).

  2. STAT5b confers gemcitabine chemoresistance and promotes cell adherence and invasiveness in pancreatic cancer cells.

  3. STAT5 (zeige STAT5A Proteine) activation by EGF (zeige EGF Proteine) constitutes an important cascade for the regulation of cell proliferation and invasion in trophoblast cells.

  4. MSM decreased the ability of STAT5b to bind the promoter of the HER2 (zeige ERBB2 Proteine) gene.

  5. Results confirm that STAT5B is mutated in T-PLL and underscore the potential therapeutical relevance of epigenetic regulator.

  6. ABL (zeige ABL1 Proteine)-N administration induced apoptosis of PC3 (zeige PCSK1 Proteine) cells in a dose-dependent manner, along with the enhanced activity of caspases and increased Bax (zeige BAX Proteine)/Bcl-2 (zeige BCL2 Proteine) ratio. Expression of KLF5 (zeige KLF5 Proteine), Stat5b and ICAM-1 (zeige ICAM1 Proteine) was significantly downregulated in PC3 (zeige PCSK1 Proteine) cells.

  7. The two STAT5 (zeige STAT5A Proteine) isoforms, STAT5a (zeige STAT5A Proteine) and STAT5b.

  8. support the concept that Jak2 (zeige JAK2 Proteine)-Stat5a (zeige STAT5A Proteine)/b signaling promotes metastatic progression of prostate cancer by inducing epithelial-to-mesenchymal transition and stem cell properties in prostate cancer cells

  9. Interference of STAT (zeige STAT1 Proteine) 5b expression by siRNA targeting enhanced the chemo-sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway-mediated cell apoptosis.

  10. Both Stat5a (zeige STAT5A Proteine)/b genetic knockdown and antiandrogen treatment induced proteasomal degradation of AR in prostate cancer cells.

Pig (Porcine) Signal Transducer and Activator of Transcription 5B (STAT5B) Interaktionspartner

  1. A study of the polymorphisms of STAT5b is presented, and the use of radiation hybrid mapping to localize the gene to chromosome 12 is presented.

Cow (Bovine) Signal Transducer and Activator of Transcription 5B (STAT5B) Interaktionspartner

  1. SNPs in JAK2 (zeige JAK2 Proteine) and STAT5B are associated with mastitis susceptibility in Chinese Holstein cattle

  2. This study suggests that growth hormone (zeige GH1 Proteine) inhibits the differentiation of bovine preadipocytes to adipocytes through STAT5b-dependent inhibition of C/EBPalpha (zeige CEBPA Proteine) and PPARgamma (zeige PPARG Proteine) expression.

  3. These results suggested that the SNPs in CD4 (zeige CD4 Proteine) and STAT5b may be potential genetic markers for SCS (zeige TWIST1 Proteine) and milk/protein (zeige CSN2 Proteine) yields selecting and warrant further functional research.

Mouse (Murine) Signal Transducer and Activator of Transcription 5B (STAT5B) Interaktionspartner

  1. STAT5B and MOF (zeige KAT8 Proteine) work as negative regulators in adipogenesis.

  2. Strong selective advantage for leukemic transformation in the background of Stat5 (zeige STAT5A Proteine) deficient hematopoiesis was permissive for faster initiation of Myc (zeige MYC Proteine)-induced transformation to B (zeige TDO2 Proteine)-ALL.

  3. liver STAT5b activation/masculinization occurred at puberty and suppression/feminization occurred during aging and in mutant mice with defects in growth hormone (zeige GH1 Proteine) signaling.

  4. Loss of STAT5b had no effect on either sex.

  5. These data provide the first definitive evidence for a contribution of STAT5a (zeige STAT5A Proteine)/b to the sex bias in pulmonary hypertension in the hypoxic mouse and implicate reduced STAT5 (zeige STAT5A Proteine) in the pathogenesis of the human disease.

  6. Data show that three hypotheses of dimer formation between STAT5 (zeige STAT5A Proteine) transcription factors STAT5A (zeige STAT5A Proteine) and STAT5B were used to explain the analytical results by a static mathematical model.

  7. Increased expression of STAT5b + PDGFB (zeige PDGFB Proteine) led to increased expression of downstream STAT5b targets.

  8. Expression of miR (zeige MLXIP Proteine)-21 is under prolactin (zeige PRL Proteine) control through the transcription factors STAT5A (zeige STAT5A Proteine)/B.

  9. non-obese-diabetic genetic background is critical to the Stat5b-mediated lymphomagenesis through regulation of Stat5 (zeige STAT5A Proteine) hyperactivation

  10. STAT5b but not STAT5a (zeige STAT5A Proteine) is the primary mediator of the action of prolactin (zeige PRL Proteine) in the hypothalamus.

STAT5B Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Alternative names and synonyms associated with STAT5B

  • signal transducer and activator of transcription 5B (STAT5B)
  • Signal transducer and activator of transcription 5B (sta5b)
  • signal transducer and activator of transcription 5B (stat5b)
  • signal transducer and activator of transcription 5.1 (stat5.1)
  • signal transducer and activator of transcription 5B (Stat5b)
  • signal transducer and activator of transcription 5B (LOC789476)
  • signal transducer and activator of transcription 5B-like (LOC100348267)
  • STAT5 Protein
  • STAT5A Protein
  • stat5b Protein

Bezeichner auf Proteinebene für STAT5B

signal transducer and activator of transcription 5A , Signal transducer and activator of transcription 5B , signal transducer and activator of transcription 5B , transcription factor STAT5B , mammary gland factor STAT5B , Signal transducer and activator of transcription 5a

GENE ID SPEZIES
454679 Pan troglodytes
100380532 Salmo salar
100566752 Anolis carolinensis
369197 Danio rerio
395556 Gallus gallus
414637 Xenopus laevis
6777 Homo sapiens
490969 Canis lupus familiaris
397340 Sus scrofa
282376 Bos taurus
20851 Mus musculus
25126 Rattus norvegicus
100716532 Cavia porcellus
789476 Bos taurus
101122961 Ovis aries
100348267 Oryctolagus cuniculus
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