anti-Meerschweinchen STAT5B Antikörper für Western Blotting

Recommended STAT5B Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Signal Transducer and Activator of Transcription 5B (STAT5B) Antikörper
  • STAT5
  • Stat5
  • stat5
  • stat5b
  • STAT5A
  • STAT5B
  • signal transducer and activator of transcription 5B
  • signal transducer and activator of transcription 5a
  • signal transducer and activator of transcription 5B S homeolog
  • Signal transducer and activator of transcription 5B
  • STAT5B
  • Stat5b
  • stat5a
  • stat5b.S
  • LOC490969
  • sta5b
  • LOC100566752
  • LOC100052954
Epitop
N-Term
34
23
10
10
7
6
5
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf, Zebrafisch
213
99
92
14
13
12
10
8
6
6
5
3
2
2
1
1
Wirt
Kaninchen
144
76
Klonalität
Polyklonal
Konjugat
Dieser STAT5B Antikörper ist unkonjugiert
4
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
165
74
62
38
29
26
17
16
7
3
3
2
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2780884
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.0849469 ABIN2780885 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
1 ABIN2779971 IHC WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
1 ABIN2779972 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN324511 WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN574773 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Signal Transducer and Activator of Transcription 5B (STAT5B) Antikörper
Epitop N-Term
(34), (23), (10), (10), (7), (6), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf, Zebrafisch
(213), (99), (92), (14), (13), (12), (10), (8), (6), (6), (5), (3), (2), (2), (1), (1)
Wirt Kaninchen
(144), (76)
Klonalität
Polyklonal
Konjugat Dieser STAT5B Antikörper ist unkonjugiert
(4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(165), (74), (62), (38), (29), (26), (17), (16), (7), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-STAT5B Antikörper

Target Details STAT5B Anwendungsinformationen Handhabung Referenzen für anti-STAT5B Antikörper (ABIN2780884) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984535.
Sequenz AVWIQAQQLQ GEALHQMQAL YGQHFPIEVR HYLSQWIESQ AWDSVDLDNP
Homologie Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 86%
Produktmerkmale This is a rabbit polyclonal antibody against STAT5B. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human STAT5B

Target Details STAT5B

Produktdetails anti-STAT5B Antikörper Anwendungsinformationen Handhabung Referenzen für anti-STAT5B Antikörper (ABIN2780884) Bilder zurück nach oben
Antigen
Andere Bezeichnung STAT5B (STAT5B Antibody Abstract)
Hintergrund The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: STAT5
Protein Interaction Partner: JAK2, KIT, SURF2, AARS, DPP9, NIF3L1, RPRD1B, ANKMY2, RPRD1A, TOM1L1, DMRTA1, AFTPH, SERTAD1, HAX1, TFG, VCAM1, UBC, INSR, IL15, APP, C18orf8, STAT5B, PRLR, PGR, FGFR2, POU2F1, ELP2, CENPJ, PPP2CA, STAP2, RARA, PTPN2, NMI, EP300, CRKL, STAT5A, GHR, NCOR2,
Protein Size: 787
Molekulargewicht 90 kDa
Gen-ID 6777
NCBI Accession NM_012448, NP_036580
UniProt P51692
Pathways JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation

Anwendungsinformationen

Produktdetails anti-STAT5B Antikörper Target Details STAT5B Handhabung Referenzen für anti-STAT5B Antikörper (ABIN2780884) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 787 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-STAT5B Antikörper Target Details STAT5B Anwendungsinformationen Referenzen für anti-STAT5B Antikörper (ABIN2780884) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-STAT5B Antikörper (ABIN2780884)

Produktdetails anti-STAT5B Antikörper Target Details STAT5B Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Mohankumar, Perry, Kannan, Kohno, Gluckman, Emerald, Lobie: "Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell." in: Endocrinology, Vol. 149, Issue 5, pp. 2219-29, 2008

Bilder

Produktdetails anti-STAT5B Antikörper Target Details STAT5B Anwendungsinformationen Handhabung Referenzen für anti-STAT5B Antikörper (ABIN2780884) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (N-Term) antibody (ABIN2780884) Anti-STAT5B antibody IHC staining of human placenta. Immunohistochemistry of formalin...
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (N-Term) antibody (ABIN2780884) Anti-STAT5B antibody IHC staining of human prostate. Immunohistochemistry of formalin...
Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (N-Term) antibody (ABIN2780884) Rabbit Anti-STAT5B Antibody Catalog Number: arp39000 Paraffin Embedded Tissue: Human ...
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (N-Term) antibody (ABIN2780884) WB Suggested Anti-STAT5B Antibody Titration: 1 ug/ml Positive Control: 293T cells lys...