Signal Transducer and Activator of Transcription 5A ELISA Kits (STAT5A)
Auf finden Sie aktuell 43 Signal Transducer and Activator of Transcription 5A (STAT5A) ELISA Kits von 13 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen STAT5A Antikörper (497) und STAT5A Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 594 STAT5A Produkte verfügbar.
AA959963, MGF, Stat5, STAT5A, STAT5A/MGF, STATA5

Am meisten referenzierte STAT5A ELISA Kits

  1. Human STAT5A ELISA Kit für Cell ELISA - ABIN1981843 : Park, Lee, Frank, Razani, Nguyen, Parlow, Russell, Hulit, Pestell, Lisanti: Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. in Molecular biology of the cell 2002 (PubMed)
    Zeige alle 3 Referenzen für 1981843

Weitere ELISA Kits für STAT5A Interaktionspartner

Human Signal Transducer and Activator of Transcription 5A (STAT5A) Interaktionspartner

  1. Molecular interactions of EphA4 (zeige EPHA4 ELISA Kits), growth hormone receptor (zeige GHR ELISA Kits), Jak2 (zeige JAK2 ELISA Kits), and STAT5B (zeige STAT5B ELISA Kits) have been described.

  2. High STAT5 phosphorylation is associated with systemic lupus erythematosus.

  3. NPM1 (zeige NPM1 ELISA Kits) downregulation by P-STAT5 is mediated by impairing the BRCA1-BARD1 (zeige BARD1 ELISA Kits) ubiquitin ligase, which controls the stability of NPM1 (zeige NPM1 ELISA Kits). In turn, decreased NPM1 (zeige NPM1 ELISA Kits) levels led to suppression of p53 (zeige TP53 ELISA Kits) expression, resulting in enhanced cell survival.

  4. All merkel cell carcinoma (MCC) cases with a good outcome expressed pSTAT5B, whereas all MCC cases with a poor outcome did not express pSTAT5B; hence, pSTAT5B expression may be an indicator of positive prognosis in patients with MCC.

  5. High STAT5A expression is associated with B-lymphoblastic lymphoma with inflammation.

  6. Results provide evidence that HDAC6 (zeige HDAC6 ELISA Kits) could regulate HMGN2 (zeige HMGN2 ELISA Kits) acetylation levels and binding to Stat5a-responsive promoters, and therefore, Stat5a transcriptional activity in breast cancer cells.

  7. Sustained STAT5 transcription factor (STAT5) phosphorylation is necessary to induce long-term interleukin 2 receptor subunit alpha (CD25 (zeige IL2RA ELISA Kits)) expression in T lymphocytes.

  8. BCR/ABL (zeige ABL1 ELISA Kits) positively regulates the expression of EZH2 (zeige EZH2 ELISA Kits) via STAT5 signaling.

  9. these results demonstrate that the oncogenic signal transducer and activator of transcription 5/Akt (zeige AKT1 ELISA Kits) pathway is a cellular target for indole-3-carbinol in chronic myeloid leukemia (zeige BCL11A ELISA Kits) cells. Thus, this clinically tested natural compound can be a potential candidate in the treatment of chronic myeloid leukemia (zeige BCL11A ELISA Kits) following confirmation with clinical studies

  10. elucidate a novel mechanism whereby the linker histone H1 (zeige H1F0 ELISA Kits) prevents STAT5 binding at promoter DNA, and the PRL (zeige PRL ELISA Kits)-induced dissociation of H1 mediated by HMGN2 (zeige HMGN2 ELISA Kits) is necessary to allow full STAT5 recruitment and promote the biological effects of PRL (zeige PRL ELISA Kits) signaling

Mouse (Murine) Signal Transducer and Activator of Transcription 5A (STAT5A) Interaktionspartner

  1. STAT5 target genes such as Oncostatin M (zeige OSM ELISA Kits) were highly expressed in FLT3 (zeige FLT3 ELISA Kits)-ITD(+) myeloid but not in FLT3 (zeige FLT3 ELISA Kits)-ITD(+) lymphoid progenitor cells; lineage-specific STAT5 activation in hematopoietic progenitor cells predicts the FLT3 (zeige FLT3 ELISA Kits)(+)-mediated leukemic phenotype in mice.

  2. findings reveal an essential role for STAT5 in maintaining lipid homeostasis in white adipose tissue and provide a rationale for future studies into the potential of STAT5 manipulation to improve outcomes in metabolic diseases.

  3. deregulation of local signal transducer and activator of transcription 5 signaling augments high fat diet-induced lipid accumulation in both muscle and liver.

  4. Data show that CUZD1 (zeige CUZD1 ELISA Kits) interacts with a complex containing JAK1 (zeige JAK1 ELISA Kits)/JAK2 (zeige JAK2 ELISA Kits) and STAT5, downstream transducers of prolactin (zeige PRL ELISA Kits) signaling in the mammary gland.

  5. The study describes an interaction network of STAT5a/LSD1 (zeige KDM1A ELISA Kits)/HDAC3 (zeige HDAC3 ELISA Kits) and a dual function of LSD1 (zeige KDM1A ELISA Kits)/HDAC3 (zeige HDAC3 ELISA Kits) on STAT5a-dependent transcription, defined by protein-protein interactions, genomic binding localization/affinity and motifs.

  6. this study shows that lipoxin A4 protects against LPS (zeige TLR4 ELISA Kits)-induced sepsis by promoting the generation and migration of splenic innate response activator B cells, and the underlying molecular mechanism may be related to STAT5 activation

  7. Study showed that suppression of STAT3 (zeige STAT3 ELISA Kits), STAT5, and STAT6 (zeige STAT6 ELISA Kits) and overexpression of the proapoptotic factor STAT1 (zeige STAT1 ELISA Kits), which provides p53 (zeige TP53 ELISA Kits)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (zeige ERBB2 ELISA Kits) tyrosine kinase receptor (zeige KDR ELISA Kits) overexpression promotes neuronal survival through activation of STAT (zeige STAT1 ELISA Kits)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (zeige STAT1 ELISA Kits)

  8. Mechanistically, RL negatively regulates Stat5 phosphorylation and Elf5 (zeige ELF5 ELISA Kits) expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin (zeige PRL ELISA Kits)/p-Stat5 pathway.

  9. Bcl6 (zeige BCL6 ELISA Kits) promoted T follicular helper cell differentiation through antagonizing IL-7R / STAT5a axis.

  10. constitutive STAT5 binding to c-Myc (zeige MYC ELISA Kits) super-enhancer might contribute to BRD2 (zeige BRD2 ELISA Kits) maintenance and thus allow sustained expression of c-Myc (zeige MYC ELISA Kits) in Ba/F3 cells transformed by STAT5-1*6.

Pig (Porcine) Signal Transducer and Activator of Transcription 5A (STAT5A) Interaktionspartner

Cow (Bovine) Signal Transducer and Activator of Transcription 5A (STAT5A) Interaktionspartner

  1. There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.

  2. Milk production traits were analyzed for each animal in the first, second, third, and fourth lactation. No genetic variability was found at STAT5A/AvaI locus. At STAT5A/MslI locus, the frequencies of T and C alleles were 0.875 and 0.125, respectively. Significant differences between genotypes were found

  3. Results indicate that SNPs in STAT5A and JAK2 (zeige JAK2 ELISA Kits) genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  4. The embryonic STAT5A gene is primarily activated by maternal gene products and the most abundant STAT5A expression occurred at the 2-cell stage blastocysts.


  6. The Stat5a gene is associated with an increase in lactation of mammary gland epithelial cells.

  7. STAT5A/AvaI polymorphism seems to be a promising indirect marker to improve milk production traits in cattle.

  8. Associations between reproduction and milk traits, and polymorphisms at the STAT5A and FGF2 (zeige FGF2 ELISA Kits) gene loci, were found with STAT5A polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).

  9. Base sequence variation in STAT5A-noncoding region was studied.

  10. The association of fertilization rate with STAT5A polymorphisms was evaluated in ocytes. Associations were found for 6 and 2 SNP. 5 SNP showed associations with both embryonic survival and fertilization rate compared with 1 SNP.

STAT5A Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Alternative names and synonyms associated with STAT5A

  • signal transducer and activator of transcription 5A (STAT5A) Elisa Kit
  • signal transducer and activator of transcription 5A (Stat5a) Elisa Kit
  • signal transducer and activator of transcription 5A-like (LOC100348518) Elisa Kit
  • signal transducer and activator of transcription 5B (STAT5B) Elisa Kit
  • AA959963 Elisa Kit
  • MGF Elisa Kit
  • Stat5 Elisa Kit
  • STAT5A Elisa Kit
  • STAT5A/MGF Elisa Kit
  • STATA5 Elisa Kit

Bezeichner auf Proteinebene für STAT5A

signal transducer and activator of transcription 5A , signal transducer and activator of transcription 5A-like , mammary gland factor STAT5A , mammary gland factor , signal transducer and activator of transcription 5 , STAT5A, Mammary Gland Factor , transcription factor STAT5B

100052904 Equus caballus
454681 Pan troglodytes
574129 Macaca mulatta
100461695 Pongo abelii
6776 Homo sapiens
20850 Mus musculus
24918 Rattus norvegicus
490968 Canis lupus familiaris
397550 Sus scrofa
282375 Bos taurus
100716811 Cavia porcellus
443419 Ovis aries
100348518 Oryctolagus cuniculus
6777 Homo sapiens
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