anti-STAT5A (STAT5A) Antikörper

Bezeichnung:
anti-Signal Transducer and Activator of Transcription 5A Antikörper (STAT5A)
Auf www.antikoerper-online.de finden Sie aktuell 497 Signal Transducer and Activator of Transcription 5A (STAT5A) Antikörper von 38 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen STAT5A Kits (43) und STAT5A Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 594 STAT5A Produkte verfügbar.
Synonyme:
AA959963, MGF, Stat5, STAT5A, STAT5A/MGF, STATA5

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Am meisten referenzierte anti-STAT5A Antikörper

  1. Dog (Canine) Monoclonal STAT5A Primary Antibody für IF, IP - ABIN967810 : Buitenhuis, Baltus, Lammers, Coffer, Koenderman: Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells. in Blood 2002 (PubMed)
    Zeige alle 5 Referenzen für 967810

  2. Human Monoclonal STAT5A Primary Antibody für WB - ABIN968702 : Gouilleux, Wakao, Mundt, Groner: Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. in The EMBO journal 1994 (PubMed)
    Zeige alle 5 Referenzen für 968702

  3. Human Monoclonal STAT5A Primary Antibody für ICS, WB - ABIN968701 : Park, Lee, Frank, Razani, Nguyen, Parlow, Russell, Hulit, Pestell, Lisanti: Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. in Molecular biology of the cell 2002 (PubMed)
    Zeige alle 5 Referenzen für 968701

  4. Human Polyclonal STAT5A Primary Antibody für EIA, IHC (p) - ABIN358237 : Martens, Uzan, Wery, Hooghe, Hooghe-Peters, Gertler: Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation. in The Journal of biological chemistry 2005 (PubMed)
    Zeige alle 5 Referenzen für 358237

  5. Human Polyclonal STAT5A Primary Antibody für IHC (p), WB - ABIN196696 : Dentelli, Del Sorbo, Rosso, Molinar, Garbarino, Camussi, Pegoraro, Brizzi: Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Zeige alle 3 Referenzen für 196696

  6. Cow (Bovine) Polyclonal STAT5A Primary Antibody für WB - ABIN2780480 : Murayama, Ohmori, Fujimura, Minami, Yasuzawa-Tanaka, Kuroda, Oie, Daitoku, Okuwaki, Nagata, Fukamizu, Kimura, Shimizu, Yanagisawa: Epigenetic control of rDNA loci in response to intracellular energy status. in Cell 2008 (PubMed)
    Zeige alle 2 Referenzen für 2780480

  7. Human Monoclonal STAT5A Primary Antibody für FACS - ABIN4898875 : Kobayashi, Watanabe, Suzuki, Furu, Ito, Ito, Matsuda, Yoshitomi: TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells. in European journal of immunology 2016 (PubMed)

  8. Human Polyclonal STAT5A Primary Antibody für ELISA, WB - ABIN1533730 : Hou, Schindler, Henzel, Wong, McKnight: Identification and purification of human Stat proteins activated in response to interleukin-2. in Immunity 1995 (PubMed)

  9. Human Polyclonal STAT5A Primary Antibody für IF (p), IHC (p) - ABIN738276 : Yang, Sun, Sun, Qi: Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte. in Molecular biology reports 2012 (PubMed)

  10. Human Polyclonal STAT5A Primary Antibody für IF, IHC (p) - ABIN389668 : Moreira, Cabezón, Gromova, Gromov, Timmermans-Wielenga, Machado, Llombart-Bosch, Kroman, Rank, Celis: Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy. in Molecular oncology 2010 (PubMed)

Weitere Antikörper gegen STAT5A Interaktionspartner

Human Signal Transducer and Activator of Transcription 5A (STAT5A) Interaktionspartner

  1. Molecular interactions of EphA4 (zeige EPHA4 Antikörper), growth hormone receptor (zeige GHR Antikörper), Jak2 (zeige JAK2 Antikörper), and STAT5B (zeige STAT5B Antikörper) have been described.

  2. High STAT5 phosphorylation is associated with systemic lupus erythematosus.

  3. NPM1 (zeige NPM1 Antikörper) downregulation by P-STAT5 is mediated by impairing the BRCA1-BARD1 (zeige BARD1 Antikörper) ubiquitin ligase, which controls the stability of NPM1 (zeige NPM1 Antikörper). In turn, decreased NPM1 (zeige NPM1 Antikörper) levels led to suppression of p53 (zeige TP53 Antikörper) expression, resulting in enhanced cell survival.

  4. All merkel cell carcinoma (MCC (zeige MCC Antikörper)) cases with a good outcome expressed pSTAT5B, whereas all MCC (zeige MCC Antikörper) cases with a poor outcome did not express pSTAT5B; hence, pSTAT5B expression may be an indicator of positive prognosis in patients with MCC (zeige MCC Antikörper).

  5. High STAT5A expression is associated with B-lymphoblastic lymphoma with inflammation.

  6. Results provide evidence that HDAC6 (zeige HDAC6 Antikörper) could regulate HMGN2 (zeige HMGN2 Antikörper) acetylation levels and binding to Stat5a-responsive promoters, and therefore, Stat5a transcriptional activity in breast cancer cells.

  7. Sustained STAT5 transcription factor (STAT5) phosphorylation is necessary to induce long-term interleukin 2 receptor subunit alpha (CD25 (zeige IL2RA Antikörper)) expression in T lymphocytes.

  8. BCR/ABL (zeige ABL1 Antikörper) positively regulates the expression of EZH2 (zeige EZH2 Antikörper) via STAT5 signaling.

  9. these results demonstrate that the oncogenic signal transducer and activator of transcription 5/Akt (zeige AKT1 Antikörper) pathway is a cellular target for indole-3-carbinol in chronic myeloid leukemia (zeige BCL11A Antikörper) cells. Thus, this clinically tested natural compound can be a potential candidate in the treatment of chronic myeloid leukemia (zeige BCL11A Antikörper) following confirmation with clinical studies

  10. elucidate a novel mechanism whereby the linker histone H1 (zeige H1F0 Antikörper) prevents STAT5 binding at promoter DNA, and the PRL (zeige PRL Antikörper)-induced dissociation of H1 mediated by HMGN2 (zeige HMGN2 Antikörper) is necessary to allow full STAT5 recruitment and promote the biological effects of PRL (zeige PRL Antikörper) signaling

Mouse (Murine) Signal Transducer and Activator of Transcription 5A (STAT5A) Interaktionspartner

  1. STAT5 target genes such as Oncostatin M (zeige OSM Antikörper) were highly expressed in FLT3 (zeige FLT3 Antikörper)-ITD(+) myeloid but not in FLT3 (zeige FLT3 Antikörper)-ITD(+) lymphoid progenitor cells; lineage-specific STAT5 activation in hematopoietic progenitor cells predicts the FLT3 (zeige FLT3 Antikörper)(+)-mediated leukemic phenotype in mice.

  2. findings reveal an essential role for STAT5 in maintaining lipid homeostasis in white adipose tissue and provide a rationale for future studies into the potential of STAT5 manipulation to improve outcomes in metabolic diseases.

  3. deregulation of local signal transducer and activator of transcription 5 signaling augments high fat diet-induced lipid accumulation in both muscle and liver.

  4. Data show that CUZD1 (zeige CUZD1 Antikörper) interacts with a complex containing JAK1 (zeige JAK1 Antikörper)/JAK2 (zeige JAK2 Antikörper) and STAT5, downstream transducers of prolactin (zeige PRL Antikörper) signaling in the mammary gland.

  5. The study describes an interaction network of STAT5a/LSD1 (zeige KDM1A Antikörper)/HDAC3 (zeige HDAC3 Antikörper) and a dual function of LSD1 (zeige KDM1A Antikörper)/HDAC3 (zeige HDAC3 Antikörper) on STAT5a-dependent transcription, defined by protein-protein interactions, genomic binding localization/affinity and motifs.

  6. this study shows that lipoxin A4 protects against LPS (zeige TLR4 Antikörper)-induced sepsis by promoting the generation and migration of splenic innate response activator B cells, and the underlying molecular mechanism may be related to STAT5 activation

  7. Study showed that suppression of STAT3 (zeige STAT3 Antikörper), STAT5, and STAT6 (zeige STAT6 Antikörper) and overexpression of the proapoptotic factor STAT1 (zeige STAT1 Antikörper), which provides p53 (zeige TP53 Antikörper)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (zeige ERBB2 Antikörper) tyrosine kinase receptor (zeige KDR Antikörper) overexpression promotes neuronal survival through activation of STAT (zeige STAT1 Antikörper)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (zeige STAT1 Antikörper)

  8. Mechanistically, RL negatively regulates Stat5 phosphorylation and Elf5 (zeige ELF5 Antikörper) expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin (zeige PRL Antikörper)/p-Stat5 pathway.

  9. Bcl6 (zeige BCL6 Antikörper) promoted T follicular helper cell differentiation through antagonizing IL-7R / STAT5a axis.

  10. constitutive STAT5 binding to c-Myc (zeige MYC Antikörper) super-enhancer might contribute to BRD2 (zeige BRD2 Antikörper) maintenance and thus allow sustained expression of c-Myc (zeige MYC Antikörper) in Ba/F3 cells transformed by STAT5-1*6.

Pig (Porcine) Signal Transducer and Activator of Transcription 5A (STAT5A) Interaktionspartner

Cow (Bovine) Signal Transducer and Activator of Transcription 5A (STAT5A) Interaktionspartner

  1. There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.

  2. Milk production traits were analyzed for each animal in the first, second, third, and fourth lactation. No genetic variability was found at STAT5A/AvaI locus. At STAT5A/MslI locus, the frequencies of T and C alleles were 0.875 and 0.125, respectively. Significant differences between genotypes were found

  3. Results indicate that SNPs in STAT5A and JAK2 (zeige JAK2 Antikörper) genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  4. The embryonic STAT5A gene is primarily activated by maternal gene products and the most abundant STAT5A expression occurred at the 2-cell stage blastocysts.

  5. INVESTIGATION OF STAT5A, FSHR (zeige FSHR Antikörper) AND LHR (zeige LHCGR Antikörper) GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS

  6. The Stat5a gene is associated with an increase in lactation of mammary gland epithelial cells.

  7. STAT5A/AvaI polymorphism seems to be a promising indirect marker to improve milk production traits in cattle.

  8. Associations between reproduction and milk traits, and polymorphisms at the STAT5A and FGF2 (zeige FGF2 Antikörper) gene loci, were found with STAT5A polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).

  9. Base sequence variation in STAT5A-noncoding region was studied.

  10. The association of fertilization rate with STAT5A polymorphisms was evaluated in ocytes. Associations were found for 6 and 2 SNP. 5 SNP showed associations with both embryonic survival and fertilization rate compared with 1 SNP.

STAT5A Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Alternative names and synonyms associated with STAT5A

  • signal transducer and activator of transcription 5A (STAT5A) Antikörper
  • signal transducer and activator of transcription 5A (Stat5a) Antikörper
  • signal transducer and activator of transcription 5A-like (LOC100348518) Antikörper
  • signal transducer and activator of transcription 5B (STAT5B) Antikörper
  • AA959963 Antikörper
  • MGF Antikörper
  • Stat5 Antikörper
  • STAT5A Antikörper
  • STAT5A/MGF Antikörper
  • STATA5 Antikörper

Bezeichner auf Proteinebene für STAT5A

signal transducer and activator of transcription 5A , signal transducer and activator of transcription 5A-like , mammary gland factor STAT5A , mammary gland factor , signal transducer and activator of transcription 5 , STAT5A, Mammary Gland Factor , transcription factor STAT5B

GENE ID SPEZIES
100052904 Equus caballus
454681 Pan troglodytes
574129 Macaca mulatta
100461695 Pongo abelii
6776 Homo sapiens
20850 Mus musculus
24918 Rattus norvegicus
490968 Canis lupus familiaris
397550 Sus scrofa
282375 Bos taurus
100716811 Cavia porcellus
443419 Ovis aries
100348518 Oryctolagus cuniculus
6777 Homo sapiens
Ausgewählte Anbieter für anti-STAT5A (STAT5A) Antikörper
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