anti-STAT3 (STAT3) Antikörper

Bezeichnung:
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) Antikörper (STAT3)
Auf www.antikoerper-online.de finden Sie aktuell 637 Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Antikörper von 40 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen STAT3 Kits (62) und STAT3 Proteine (34) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 761 STAT3 Produkte verfügbar.
Synonyme:
1110034C02Rik, aprf, AW109958, hies, stat3, wu:fc15d02, wu:fl59g06, Xstat3, z-Stat3

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Am meisten referenzierte anti-STAT3 Antikörper

  1. Human Polyclonal STAT3 Primary Antibody für IHC (p), WB - ABIN389665 : Schick, Oakeley, Hynes, Badache: TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity. in The Journal of biological chemistry 2004 (PubMed)
    Zeige alle 8 Referenzen für 389665

  2. Human Polyclonal STAT3 Primary Antibody für EIA, IHC (p) - ABIN358234 : Wang, Wang, Zhang, Huang, Liao, Fuller: Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas. in Laboratory investigation; a journal of technical methods and pathology 2004 (PubMed)
    Zeige alle 5 Referenzen für 358234

  3. Cow (Bovine) Polyclonal STAT3 Primary Antibody für IF, IHC - ABIN2780479 : Ohbayashi, Kawakami, Muromoto, Togi, Ikeda, Kamitani, Sekine, Honjoh, Matsuda: The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction. in Biochemical and biophysical research communications 2008 (PubMed)
    Zeige alle 4 Referenzen für 2780479

  4. Human Polyclonal STAT3 Primary Antibody für FACS, IF (p) - ABIN738261 : Yang, Sun, Sun, Qi: Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte. in Molecular biology reports 2012 (PubMed)
    Zeige alle 3 Referenzen für 738261

  5. Cow (Bovine) Polyclonal STAT3 Primary Antibody für IHC, WB - ABIN2792239 : Suen, Uddin, Prow, Bowen, Hall, Bielefeldt-Ohmann: Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits. in Virology 2016 (PubMed)
    Zeige alle 2 Referenzen für 2792239

  6. Human Polyclonal STAT3 Primary Antibody für IF (p), IHC (p) - ABIN746198 : Song, Sun, Liu, Liu, Chen, Zhang, Zheng, Zhang: STAT3, p-STAT3 and HIF-1α are associated with vasculogenic mimicry and impact on survival in gastric adenocarcinoma. in Oncology letters 2014 (PubMed)

  7. Human Polyclonal STAT3 Primary Antibody für ELISA, WB - ABIN185692 : Palmqvist, Glover, Hsu, Lu, Bossen, Piret, Humphries, Helgason: Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. in Stem cells (Dayton, Ohio) 2005 (PubMed)

  8. Human Monoclonal STAT3 Primary Antibody für WB - ABIN1449165 : Yamashita, Miyagi, Carmany-Rampey, Shimizu, Fujii, Schier, Hirano: Stat3 Controls Cell Movements during Zebrafish Gastrulation. in Developmental cell 2002 (PubMed)

  9. Human Polyclonal STAT3 Primary Antibody für IHC, ELISA - ABIN1531975 : Catlett-Falcone, Landowski, Oshiro, Turkson, Levitzki, Savino, Ciliberto, Moscinski, Fernández-Luna, Nuñez, Dalton, Jove: Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. in Immunity 1999 (PubMed)

Weitere Antikörper gegen STAT3 Interaktionspartner

Mouse (Murine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Interaktionspartner

  1. The results suggest that biochanin A activates RORgamma-dependent IL-17 (zeige IL17A Antikörper) transcription through the enhancement of STAT3 phosphorylation and STAT3-mediated recruitment of NCOA1 (zeige NCOA1 Antikörper) to RORgamma.

  2. Loss of Sav1 (zeige SAV1 Antikörper) induced Stat3 activation and a senescence-associated secretory phenotype (SASP (zeige ASPRV1 Antikörper)) that coincided with the development of tubulointerstitial fibrosis.

  3. this study shows that STAT3-deficient Th9 cells have increased IL-9 (zeige IL9 Antikörper) production that is maintained for longer in culture than IL-9 (zeige IL9 Antikörper) in control cultures

  4. myeloid-specific Stat3 deletion causes defects in multiple aspects of the immune system

  5. LIF (zeige LIF Antikörper)/STAT3 and MEK (zeige MDK Antikörper)/ERK (zeige EPHB2 Antikörper) signaling in naive embryonic stem cell pluripotency, is reported.

  6. apoA-I (zeige APOA1 Antikörper)/ABCA1 (zeige ABCA1 Antikörper)-mediated cholesterol efflux without STAT3 activation can reduce proinflammatory cytokine expression in macrophages.

  7. IL-6 (zeige IL6 Antikörper) can directly induce the transition of HSCs toward myofibroblast-like cells. The effect is mediated by the activation of both MAPK (zeige MAPK1 Antikörper) and JAK (zeige JAK3 Antikörper)/STAT (zeige STAT1 Antikörper) signaling pathways. Elimination of either MAPK (zeige MAPK1 Antikörper) or JAK (zeige JAK3 Antikörper)/STAT (zeige STAT1 Antikörper) signaling pathways inhibits HSC (zeige FUT1 Antikörper) stimulation

  8. These findings also identify STAT3 as a therapeutic target against viral infection and highlight it as an essential pathway component for endogenous and therapeutic IFN-alpha (zeige IFNA Antikörper) responsiveness.

  9. As a result of Tumour-associated macrophages (TAMs)-induced activation of the STAT3 pathway, murine 5T33MM cells are sensitized to AZD1480 treatment.

  10. Stat3-mediated regulation of expression of members of the calcium-activated chloride channel (zeige CLCA4 Antikörper) regulator (zeige CLNS1A Antikörper) (CLCA) family of proteins during involution and mammary carcinogenesis.

Human Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Interaktionspartner

  1. Activated STAT3 upregulates the expression of GPx1 (zeige GPX1 Antikörper) and SOD2 (zeige SOD2 Antikörper), which reduce the intracellular ROS (zeige ROS1 Antikörper) levels in Burkitt lymphoma.

  2. Peritoneal membrane dysfunction in long-term peritoneal dialysis patients may result from IL-6 (zeige IL6 Antikörper) promotion of epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2 (zeige JAK2 Antikörper)/STAT3 signaling pathway.

  3. Data suggest that C-terminal truncated hepatitis B virus X protein (HBx-DeltaC1) enhances liver cancer stem cell (CSC) properties through Stat3/Nanog (zeige NANOG Antikörper) cascade, and insight for the therapeutic intervention for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)).

  4. High STAT3 expression is associated with Hepatocellular Carcinoma.

  5. Phosphorylation of STAT3 was decreased in NRDC (zeige NRD1 Antikörper)-depleted Huh-7 spheroids.

  6. Mutation inactivating STAT3 gene is associated with Breast Cancer Metastasis.

  7. The activation of NF-kappaB (zeige NFKB1 Antikörper) and STAT3 signalling-dependent pro-inflammatory cytokine expression.

  8. High STAT3 expression is associated with glioblastomas.

  9. High STAT3 expression is associated with nasopharyngeal cancer.

  10. In this review, we focus on the reciprocal regulation and roles of microRNAs and signal transducer and activator of transcription 3 in cancer, as well as describe current research progress on this relationship. A better understanding of this relationship may facilitate in the identification of targets for clinical therapeutics.

Cow (Bovine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Interaktionspartner

  1. STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.

  2. Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate

  3. results show for the first time that interleukin-6 (zeige IL6 Antikörper) (IL), in the presence of its soluble receptor (zeige IFNAR1 Antikörper) (sIL (zeige STIL Antikörper)-6R), induces activation of JAK1 (zeige JAK1 Antikörper), JAK2 (zeige JAK2 Antikörper), and STAT1 (zeige STAT1 Antikörper)/STAT3 proteins in bovine articular chondrocytes

  4. peroxynitrite causes increased expression of VEGF (zeige VEGFA Antikörper) in vascular endothelial cells by a process that requires the activation of STAT3

  5. Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (zeige NOX1 Antikörper)-mediated activation of STAT3.

Pig (Porcine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Interaktionspartner

  1. this study shows that weaning caused severe inflammation associated with activation of the STAT3 pathway in the jejunum of piglets

  2. maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 (zeige CCND2 Antikörper) and PSEN1 (zeige PSEN1 Antikörper) genes via a STAT3-dependent pathway

  3. Studied effect of recombinant porcine leukemia inhibitory factor (zeige LIF Antikörper) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (zeige FTH1 Antikörper)-supplemented media.

  4. Data suggest that IL-6 (interleukin 6 (zeige IL6 Antikörper)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (zeige IL6 Antikörper)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).

  5. the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.

  6. Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.

  7. STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways

  8. Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.

Rabbit Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Interaktionspartner

  1. This is the first report of the genetic polymorphisms of the JAK1 (zeige JAK1 Antikörper) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.

Guinea Pig Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Interaktionspartner

  1. Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.

  2. Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (zeige MMP2 Antikörper) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.

Zebrafish Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) Interaktionspartner

  1. Stat3 regulates cell proliferation and axis extension in part via upregulation of Cdc25a (zeige CDC25A Antikörper) expression during oogenesis. Accordingly, restoring Cdc25a (zeige CDC25A Antikörper) expression in stat3 mutants partially suppressed cell proliferation and gastrulation defects.

  2. PTPN9 (zeige PTPN9 Antikörper) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (zeige GATA1 Antikörper) and ZBP-89 (zeige ZNF148 Antikörper).

  3. Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.

  4. Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.

  5. This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.

  6. The results of this study suggested that the stat3/socs3 (zeige SOCS3 Antikörper) pathway is a key response in all tissue regeneration in zebrafish.

  7. stat3, a known oncogene (zeige RAB1A Antikörper) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.

  8. Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (zeige PRCP Antikörper) in neighboring cells during zebrafish gastrulation.

STAT3 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT3

  • signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3) Antikörper
  • signal transduction and activation of transcription 3 (stat3) Antikörper
  • signal transducer and activator of transcription 3 (acute-phase response factor) (stat3) Antikörper
  • signal transducer and activator of transcription 3 (Stat3) Antikörper
  • signal transducer and activator of transcription 3 (acute-phase response factor) (Stat3) Antikörper
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1 (stat3.1) Antikörper
  • 1110034C02Rik Antikörper
  • aprf Antikörper
  • AW109958 Antikörper
  • hies Antikörper
  • stat3 Antikörper
  • wu:fc15d02 Antikörper
  • wu:fl59g06 Antikörper
  • Xstat3 Antikörper
  • z-Stat3 Antikörper

Bezeichner auf Proteinebene für STAT3

signal transducer and activator of transcription 3 (acute-phase response factor) , signal transducer and activator of transcription 3 , signal transduction and activation of transcription 3 , Signal transducer and activator of transcription 3 , signal transducer and activator of transcription 3-like , acute phase response factor , acute-phase response factor , DNA-binding protein APRF , Protein Stat3 , signal transducer and activator of transcription 3.1 , stat 3

GENE ID SPEZIES
100011382 Monodelphis domestica
100171541 Pongo abelii
100380714 Salmo salar
100469938 Ailuropoda melanoleuca
100566559 Anolis carolinensis
100598877 Nomascus leucogenys
20848 Mus musculus
6774 Homo sapiens
25125 Rattus norvegicus
490967 Canis lupus familiaris
508541 Bos taurus
733648 Sus scrofa
420027 Gallus gallus
574128 Macaca mulatta
454682 Pan troglodytes
100348778 Oryctolagus cuniculus
100717084 Cavia porcellus
100294659 Ovis aries
779100 Xenopus laevis
30767 Danio rerio
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