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anti-Mouse (Murine) STAT3 Antikörper:
anti-Human STAT3 Antikörper:
anti-Rat (Rattus) STAT3 Antikörper:
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Human Polyclonal STAT3 Primary Antibody für IHC, WB - ABIN361960
Yamaguchi, Zhu, Yu, Sasaki, Umetsu, Kidachi, Ryoyama: Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation. in Toxicology 2006
Show all 9 Pubmed References
Human Polyclonal STAT3 Primary Antibody für WB - ABIN3043299
Zheng, Liu, Liu, Ma, Zhou, Chen, Chang, Wang, Yang, He: Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH?SY5Y human neuroblastoma cells. in Molecular medicine reports 2014
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Human Polyclonal STAT3 Primary Antibody für ICC, IHC (p) - ABIN3044335
Khan, Li, Ahmad Khan, Rasul, Nawaz, Sun, Zheng, Ma: Alantolactone induces apoptosis in HepG2 cells through GSH depletion, inhibition of STAT3 activation, and mitochondrial dysfunction. in BioMed research international 2013
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Human Polyclonal STAT3 Primary Antibody für IHC (p), WB - ABIN196690
Fan, Ballou, Lin: Phospholipase C-independent activation of glycogen synthase kinase-3beta and C-terminal Src kinase by Galphaq. in The Journal of biological chemistry 2003
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Human Polyclonal STAT3 Primary Antibody für IF, IHC - ABIN361962
Yamaguchi, Zhu, Yu, Sasaki, Umetsu, Kidachi, Ryoyama et al.: Serum-free mouse embryo cells generate a self-sustaining feedback loop for an astrocyte marker protein and respond to cytokines and bisphenol A in accordance with the subtle difference in their ... in Cell biology international 2007
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Human Polyclonal STAT3 Primary Antibody für WB - ABIN1881850
Li, Cheung, Evans, Shaw: Modulation of gene expression and tumor cell growth by redox modification of STAT3. in Cancer research 2010
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Chicken Monoclonal STAT3 Primary Antibody für IF, IP - ABIN967808
Buitenhuis, Baltus, Lammers, Coffer, Koenderman: Signal transducer and activator of transcription 5a (STAT5a) is required for eosinophil differentiation of human cord blood-derived CD34+ cells. in Blood 2002
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Chicken Monoclonal STAT3 Primary Antibody für IF, IP - ABIN967809
Zhong, Wen, Darnell: Stat3 and Stat4: members of the family of signal transducers and activators of transcription. in Proceedings of the National Academy of Sciences of the United States of America 1994
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Human Polyclonal STAT3 Primary Antibody für IHC (p), WB - ABIN389665
Schick, Oakeley, Hynes, Badache: TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity. in The Journal of biological chemistry 2004
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Human Polyclonal STAT3 Primary Antibody für FACS, IF (p) - ABIN732638
Yang, Sun, Sun, Qi: Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte. in Molecular biology reports 2012
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Stat3 regulates self-renewal of adult muscle satellite cells during injury-induced muscle regeneration through various partners, such as Pax7 (zeige PAX7 Antikörper).
cytokine-activated STAT3 and STAT6 cooperate in macrophages to promote a secretory phenotype that enhances tumor progression in a cathepsin-dependent manner.
this study shows that the upregulation of IL-10Ra (zeige IL10RA Antikörper) by STAT3 contributed to the suppressive function of dendritic cellss following histone deacetylase (zeige HDAC1 Antikörper) inhibition
APPL1 (zeige APPL1 PLURAL_@2012@)-SirT1 (zeige SIRT1 PLURAL_@2012@)-STAT3 pathway mediated adiponectin (zeige ADIPOQ PLURAL_@2012@) signaling in primary hepatocytes.
HDL (zeige HSD11B1 Antikörper)-associated sphingosine 1-phosphate inhibits macrophage apoptosis by stimulating STAT3 activity and survivin (zeige BIRC5 Antikörper) expression.
loss of Fyn (zeige FYN Antikörper) in the kidney prevents unilateral ureteral obstruction-induced tubulointerstitial fibrosis, mediated by a reduction in STAT3 phosphorylation
Results provide genetic evidence indicating that mTOR (zeige FRAP1 Antikörper) and Raptor (zeige RPTOR Antikörper) are required for sensory axon regeneration enhanced by peripheral lesions in mice, whereas Rictor (zeige RICTOR Antikörper) plays a minor role. The peripheral lesion activates rapamycin-resistant mTOR (zeige FRAP1 Antikörper) signaling to modulate Stat3 activity and further promotes axon regeneration.
These data describe a novel regulatory mechanism through which STAT3 and the Ikaros (zeige IKZF1 Antikörper) zinc finger transcription factors Aiolos (zeige IKZF3 Antikörper) and Ikaros (zeige IKZF1 Antikörper) cooperate to regulate Bcl-6 (zeige BCL6 Antikörper) expression.
Transplantation from GRIM19 (zeige NDUFA13 Antikörper)-overexpressing cells downregulated the expression of nuclear factor of activated T cells (NFATc1 (zeige NFATC1 Antikörper)) but promoted the expression of regulator of calcineurin (RCAN)3 (zeige RCAN3 Antikörper) while downregulating NFAT (zeige NFATC1 Antikörper)-dependent cytokine gene expression.
Data suggest MHV68 RTA (zeige RBM9 Antikörper) specifically recognizes and recruits activated (phosphorylated at Tyr705) host Stat3 during lytic phase of infection; Stat3, once phosphorylated at Tyr705, avidly binds consensus target site in promoters of regulated genes. (MHV68 = murine gammaherpesvirus 68; RTA (zeige RBM9 Antikörper) = replication and transcription activator coded for by ORF50; Stat3 = signal transducer and activator of transcription 3 protein)
High STAT3 expression is associated with recurrence in Glioma.
IL-27 (zeige IL27 Antikörper) stimulation activated STAT1 (zeige STAT1 Antikörper) and STAT3 in HeLa and T98G cells, suggesting that IL-27 (zeige IL27 Antikörper) engages the STAT1 (zeige STAT1 Antikörper)/3 pathway, which then leads to the upregulation of IL-6 (zeige IL6 Antikörper), IP-10 (zeige CXCL10 Antikörper), and MIG (zeige CXCL9 Antikörper)
STAT3 and ATG12 (zeige ATG12 Antikörper) are targets of miR (zeige MLXIP Antikörper)-454-3p.
luteolin inhibited STAT3 activation through disrupting the binding of HSP-90 to STAT3, which promoted its interaction to SHP-1.
High STAT3 expression is associated with B-cell lymphoma.
PAI-1 (zeige SERPINE1 Antikörper) was identified as the target gene of miR (zeige MLXIP Antikörper)-34a and activated the Stat3 signaling pathway to promote epithelial-mesenchymal transition in non-small cell lung cancer cells.
These results suggest that miR146a may regulate SOCS1 (zeige SOCS1 Antikörper)/STAT3 and cytokine signalling in monocytes, directing T-cell differentiation and balancing immune clearance and immune injury during chronic viral infection.
High STAT3 expression is associated with neuroblastoma (zeige ARHGEF16 Antikörper).
simvastatin also increased p21 (zeige CDKN1A Antikörper) and p27 (zeige PAK2 Antikörper) expression in tumor sections by reducing Skp2 expression and inducing AMPK (zeige PRKAA1 Antikörper) activation and STAT3 suppression in the same tumor tissues.
Overexpression of REP1 (zeige CHM Antikörper) in BEAS-2B cells enhanced cell growth and anchorage-independent colony formation with little increase in EGFR (zeige EGFR Antikörper) level and STAT3 activation.
STA3 (zeige ARHGEF3 Antikörper) facilitates TLR4 (zeige TLR4 Antikörper)-dependent IL-6 (zeige IL6 Antikörper) and IL-8 (zeige IL8 Antikörper) production via IL-6 (zeige IL6 Antikörper) receptor-positive feedback in endometrial cells.
STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.
Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate
results show for the first time that interleukin-6 (zeige IL6 Antikörper) (IL), in the presence of its soluble receptor (zeige IFNAR1 Antikörper) (sIL (zeige STIL Antikörper)-6R), induces activation of JAK1 (zeige JAK1 Antikörper), JAK2 (zeige JAK2 Antikörper), and STAT1 (zeige STAT1 Antikörper)/STAT3 proteins in bovine articular chondrocytes
peroxynitrite causes increased expression of VEGF (zeige VEGFA Antikörper) in vascular endothelial cells by a process that requires the activation of STAT3
Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (zeige NOX1 Antikörper)-mediated activation of STAT3.
this study shows that weaning caused severe inflammation associated with activation of the STAT3 pathway in the jejunum of piglets
maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 (zeige CCND2 Antikörper) and PSEN1 (zeige PSEN1 Antikörper) genes via a STAT3-dependent pathway
Studied effect of recombinant porcine leukemia inhibitory factor (zeige LIF Antikörper) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (zeige FTH1 Antikörper)-supplemented media.
Data suggest that IL-6 (interleukin 6 (zeige IL6 Antikörper)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (zeige IL6 Antikörper)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).
the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.
Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.
STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways
Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.
This is the first report of the genetic polymorphisms of the JAK1 (zeige JAK1 Antikörper) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.
Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.
Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (zeige MMP2 Antikörper) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.
Stat3 regulates cell proliferation and axis extension in part via upregulation of Cdc25a (zeige CDC25A Antikörper) expression during oogenesis. Accordingly, restoring Cdc25a (zeige CDC25A Antikörper) expression in stat3 mutants partially suppressed cell proliferation and gastrulation defects.
PTPN9 (zeige PTPN9 Antikörper) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (zeige GATA1 Antikörper) and ZBP-89 (zeige ZNF148 Antikörper).
Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.
Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.
This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.
The results of this study suggested that the stat3/socs3 (zeige SOCS3 Antikörper) pathway is a key response in all tissue regeneration in zebrafish.
stat3, a known oncogene (zeige RAB1A Antikörper) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.
Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (zeige PRCP Antikörper) in neighboring cells during zebrafish gastrulation.
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
signal transducer and activator of transcription 3 (acute-phase response factor)
, signal transducer and activator of transcription 3
, signal transduction and activation of transcription 3
, Signal transducer and activator of transcription 3
, signal transducer and activator of transcription 3-like
, acute phase response factor
, acute-phase response factor
, DNA-binding protein APRF
, Protein Stat3
, signal transducer and activator of transcription 3.1
, stat 3