Signal Transducer and Activator of Transcription 1, 91kDa ELISA Kits (STAT1)
Auf finden Sie aktuell 46 Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) ELISA Kits von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen STAT1 Antikörper (635) und STAT1 Proteine (21) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 747 STAT1 Produkte verfügbar.
2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, H2RSP, IMUP, IMUP-1, IMUP-2, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, STAT4, STAT91, XStat1
list all ELISA KIts Gen GeneID UniProt
STAT1 72275  
STAT1 25124  
STAT1 6772 P42224

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Am meisten referenzierte STAT1 ELISA Kits

  1. Human STAT1 ELISA Kit für Cell ELISA - ABIN1981837 : Nakano, Fujii, Hashimoto, Yukawa, Yoshifuji, Ohmura, Nakaizumi, Mimori: Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells. in Clinical and experimental immunology 2012 (PubMed)

Weitere ELISA Kits für STAT1 Interaktionspartner

Mouse (Murine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. In cultured macrophages, LPS (zeige TLR4 ELISA Kits)-induced expression of monocyte chemoattractant protein (MCP)-1 (zeige CPT1B ELISA Kits) was suppressed by NaN3 through inhibition of STAT1 and IkappaBzeta (zeige NFKBIZ ELISA Kits) activities.

  2. Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting were used to detect the mRNA and protein expressions of p-p38MAPK (zeige MAPK14 ELISA Kits), AAT, signal transducer and activator of transcription 1 (STAT1) and activating transcription factor2 (ATF2 (zeige ATF2 ELISA Kits))

  3. This secreted effector, toxoplasma inhibitor of STAT1-dependent transcription (TgIST), translocates to the host cell nucleus, where it recruits mouse Mi-2 (zeige CHD4 ELISA Kits)/NuRD to STAT1-dependent promoters, resulting in altered chromatin and blocked transcription.

  4. Microbiome depletion as a result of broad-spectrum antibiotic treatment disrupts basal Stat1 signaling and alters T-cell homeostasis, leading to impaired progenitor maintenance and granulocyte maturation.

  5. We revealed that in mouse mesenchymal stem cells IFN-gamma-induced (zeige SAMHD1 ELISA Kits) immunoregulation is mediated by early phosphorylation of signal transducer and activator of transcription (STAT) 1 and STAT3 (zeige STAT3 ELISA Kits), which is significantly enhanced by an extracellular signal-regulated kinase 1/2 (zeige MAPK3 ELISA Kits)-dependent mTOR (zeige FRAP1 ELISA Kits) inhibition, thereby promoting pSTAT1 nuclear translocation.

  6. these results define a differential regulation of TLR-mediated activation and differentiation of MZ B cells by STAT1 and reveal a STAT1-dependent, but IFN-independent, antibody response during infection and inflammation.

  7. B cell-intrinsic IFN-gamma (zeige IFNG ELISA Kits) receptor (IFN-gammaR (zeige IFNGR1 ELISA Kits)) and STAT1 signaling are required for Spontaneously developed germinal centers and follicular T helper cell (Tfh cell) development.

  8. Inhibitor-sensitive tyrosine kinase (zeige TYRO3 ELISA Kits) controls the population heterogeneity of basal STAT1 activity in Ube1l (zeige UBA7 ELISA Kits) deficient fibroblasts.

  9. The studies presented here reveal that the ability of IFN-gamma (zeige IFNG ELISA Kits) to inhibit parasite replication in astrocytes in vitro is dependent on signal transducer and activator of transcription 1 (STAT1) and that mice that specifically lack STAT1 in astrocytes are unable to limit parasite replication in the central nervous system (CNS).

  10. We found that STAT-1(-/-) MRL lpr (zeige FAS ELISA Kits) mice, but not IRF-9 (zeige IRF9 ELISA Kits)(-/-) or IFNAR-2 (zeige IFNAR2 ELISA Kits)(-/-) mice, developed interstitial nephritis characterized by infiltration with RORgammat-positive lymphocytes, macrophages, and eosinophils. Despite pronounced interstitial kidney disease and abnormal kidney function, STAT-1(-/-) mice had decreased proteinuria, glomerulonephritis, and autoantibody production.

Human Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. MFSD2B, CCL20 (zeige CCL20 ELISA Kits) and STAT1, or STARD7 and ZNF512 (zeige ZNF512 ELISA Kits) genes may be risk or protect factors in prognosis of ADC (zeige ADC ELISA Kits); HTR2B (zeige HTR2B ELISA Kits), DPP4 (zeige DPP4 ELISA Kits), and TGFBRAP1 (zeige TGFBRAP1 ELISA Kits) genes may be risk factors in prognosis of SQC (zeige QPCT ELISA Kits).

  2. In cultured macrophages, LPS (zeige IRF6 ELISA Kits)-induced expression of monocyte chemoattractant protein (MCP)-1 (zeige CCL2 ELISA Kits) was suppressed by NaN3 through inhibition of STAT1 and IkappaBzeta (zeige NFKBIZ ELISA Kits) activities.

  3. Functional analysis of NK cells shows a significant impairment of cytolytic and degranulation activities in chronic mucocutaneous candidiasis patients with STAT1 GOF mutations

  4. Mechanistic investigations reveal that AJUBA specifically binds the FERM domain of JAK1 to dissociate JAK1 from the IFNgamma recepter, resulting in an inhibition of STAT1 phosporylation and concomitantly its nuclear translocation. Clinically, the level of AJUBA in CRC specimens is negatively correlated with the levels of IFIT2 and pSTAT1

  5. Low STAT1 expression is associated with Pancreatic cancer.

  6. STAT1 and IRF1 (zeige IRF1 ELISA Kits) collaborate to induce interferon-gamma (zeige IFNG ELISA Kits) stimulated genes (ISGs), but the extent to which they act alone or together is unclear.This study provides strong evidence for widespread cooperation between STAT1 and IRF1 (zeige IRF1 ELISA Kits) at ISGs, and suggests that in silico predictions reliably predict the effect of nucleotide variants on binding in vivo.

  7. IFITM1 suppression blocks proliferation and invasion of aromatase (zeige CYP19A1 ELISA Kits) inhibitor-resistant breast cancer in vivo by JAK (zeige JAK3 ELISA Kits)/STAT1-mediated induction of p21 (zeige CDKN1A ELISA Kits).

  8. This study reports a new role for SETD2 in promoting IFNalpha-induced antiviral immune response by directly methylating STAT1 on lysine 525 and catalyzing H3K36me3 on the promoters of some IFN-stimulated genes (ISGs such as ISG15) to activate gene transcription. Thus, SETD2 enhances host antiviral immunity by strengthening IFNalpha signaling both post-translationally and epigenetically.

  9. STAT1 gain-of-function mutations underlie Autosomal dominant chronic mucocutaneous candidiasis, as well as an unexpectedly wide range of other clinical features, including not only a variety of infectious and autoimmune diseases, but also cerebral aneurysms and carcinomas that confer a poor prognosis.

  10. Six different heterozygous mutations in STAT1 were detected in the seven patients (Patients 3 and 4 shared identical mutations). Three of these mutations were recurrent variants (p.R274Q, p.K388E and p.P329L), whereas the other three (p.N357D, p.M202T, and p.T437I), involving both the coiled coil domain (CCD (zeige RUNX2 ELISA Kits)) and DNA binding domain (DBD), have not been reported previously.

Pig (Porcine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (zeige IFNA ELISA Kits) response by inducing STAT1 degradation.

  2. this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets

  3. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (zeige JAK3 ELISA Kits)-STAT1) signaling pathway.

  4. Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 (zeige STAT2 ELISA Kits) nuclear translocation.

  5. Nsp1beta inhibits interferon-activated (zeige MNDA ELISA Kits) STAT1/STAT2 (zeige STAT2 ELISA Kits) signal transduction by inducing karyopherin-alpha1 degradation.

  6. STAT1 is involved in mediating the action of ghrelin (zeige GHRL ELISA Kits) on ovarian cell functions.

  7. the majority of the STAT1/STAT2 (zeige STAT2 ELISA Kits)/IRF9 (zeige IRF9 ELISA Kits) (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked

  8. Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation.

  9. Nitric oxide-dependent increase in caspase-8 (zeige CASP8 ELISA Kits) mRNA levels is associated with phosphorylation of STAT-1 at Ser (zeige SIGLEC1 ELISA Kits)-727 and STAT1 binding to the caspase-8 (zeige CASP8 ELISA Kits) promoter in cultured lung endothelial cells.

  10. Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation.

Cow (Bovine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. Report interferon-tau dependent STAT1 regulation of SOCS (zeige CISH ELISA Kits) genes in bovine endometrium during estrus cycle and embryo implantation.

  2. the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate

  3. results show for the first time that interleukin-6 (zeige IL6 ELISA Kits) (IL), in the presence of its soluble receptor (zeige IFNAR1 ELISA Kits) (sIL (zeige STIL ELISA Kits)-6R), induces activation of JAK1 (zeige JAK1 ELISA Kits), JAK2 (zeige JAK2 ELISA Kits), and STAT1/STAT3 (zeige STAT3 ELISA Kits) proteins in bovine articular chondrocytes

  4. Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein (zeige CSN2 ELISA Kits) synthesis and fat metabolism.

  5. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2 (zeige STAT2 ELISA Kits).

STAT1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT1

  • signal transducer and activator of transcription 1, 91kDa (STAT1) Elisa Kit
  • RIKEN cDNA 2200002D01 gene (2200002D01Rik) Elisa Kit
  • signal transducer and activator of transcription 1 (Stat1) Elisa Kit
  • signal transducer and activator of transcription 1, 91kDa (stat1) Elisa Kit
  • signal transducer and activator of transcription 4 (stat4) Elisa Kit
  • 2010005J02Rik Elisa Kit
  • AA408197 Elisa Kit
  • CANDF7 Elisa Kit
  • DD6G4-4 Elisa Kit
  • dZ182H3.3 Elisa Kit
  • H2RSP Elisa Kit
  • IMUP Elisa Kit
  • IMUP-1 Elisa Kit
  • IMUP-2 Elisa Kit
  • ISGF-3 Elisa Kit
  • si:by51f19.1 Elisa Kit
  • si:by134g18.2 Elisa Kit
  • si:dz73o4.2 Elisa Kit
  • si:dz182h3.3 Elisa Kit
  • si:dz199m19.1 Elisa Kit
  • STAT Elisa Kit
  • STAT1 Elisa Kit
  • STAT4 Elisa Kit
  • STAT91 Elisa Kit
  • XStat1 Elisa Kit

Bezeichner auf Proteinebene für STAT1

signal transducer and activator of transcription 1-alpha/beta , HAI-2 related small protein , signal transducer and activator of transcription-1 , transcription factor ISGF-3 components p91/p84 , signal transducer and activator of transcription 4 , signal transducer and activator of transcription 1 , transcription factor ISGF-3 , activator of transcription , signal transduction

100307049 Ovis aries
72275 Mus musculus
20846 Mus musculus
25124 Rattus norvegicus
6772 Homo sapiens
424044 Gallus gallus
488449 Canis lupus familiaris
396655 Sus scrofa
510814 Bos taurus
398324 Xenopus laevis
100343893 Oryctolagus cuniculus
368519 Danio rerio
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