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anti-STAT1 (STAT1) Antikörper

Bezeichnung:
anti-Signal Transducer and Activator of Transcription 1, 91kDa Antikörper (STAT1)
Auf www.antikoerper-online.de finden Sie aktuell 604 Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Antikörper von 36 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen STAT1 Kits (46) und STAT1 Proteine (21) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 715 STAT1 Produkte verfügbar.
Synonyme:
2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, H2RSP, IMUP, IMUP-1, IMUP-2, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, STAT4, STAT91, XStat1
Alle Antikörper anzeigen Gen GeneID UniProt
STAT1 72275  
STAT1 25124  
STAT1 6772 P42224

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Am meisten referenzierte anti-STAT1 Antikörper

  1. Human Polyclonal STAT1 Primary Antibody für EIA, IHC (p) - ABIN358231 : Garcin, Marq, Iseni, Martin, Kolakofsky: A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability. in Journal of virology 2004 (PubMed)
    Zeige alle 5 Referenzen für ABIN358231

  2. Human Polyclonal STAT1 Primary Antibody für EIA, IF - ABIN500815 : Leonard, OShea: Jaks and STATs: biological implications. in Annual review of immunology 1998 (PubMed)
    Zeige alle 4 Referenzen für ABIN500815

  3. Human Polyclonal STAT1 Primary Antibody für IF, IHC - ABIN1533008 : Durbin, Hackenmiller, Simon, Levy: Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. in Cell 1996 (PubMed)
    Zeige alle 2 Referenzen für ABIN1533008

  4. Human Monoclonal STAT1 Primary Antibody für IHC (p), IP - ABIN269146 : Kovarik, Boudny, Kocak, Lauerova, Fait, Vagundova: Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. in International journal of molecular medicine 2003 (PubMed)
    Zeige alle 2 Referenzen für ABIN269146

  5. Cow (Bovine) Polyclonal STAT1 Primary Antibody für WB - ABIN2777895 : Battle, Lynch, Frank: Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis. in Cancer research 2006 (PubMed)
    Zeige alle 2 Referenzen für ABIN2777895

  6. Human Polyclonal STAT1 Primary Antibody für ELISA, WB - ABIN1533729 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

Weitere Antikörper gegen STAT1 Interaktionspartner

Mouse (Murine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. IFN-I can mediate ISG expression inmixed glial cell cultures (MGCs) via ISGF3 (zeige IRF9 Antikörper)-independent signaling pathways but with reduced efficiency, with delayed and prolonged kinetics, and is more dependent on STAT1 and STAT2 (zeige STAT2 Antikörper) than IRF9 (zeige IRF9 Antikörper); and 2) signaling pathways not involving STAT1, STAT2 (zeige STAT2 Antikörper), or IRF9 (zeige IRF9 Antikörper) play a minor role only in mediating IFN-alpha (zeige IFNA Antikörper)-stimulated genes expression in MGCs.

  2. These results demonstrate a novel mechanism by which STAT1 negatively regulates ULK1 (zeige ULK1 Antikörper) expression and autophagy.

  3. a novel negative feedback loop mediated by STAT3 (zeige STAT3 Antikörper)-SOCS3 (zeige SOCS3 Antikörper), which is tightly controlled by SENP1 (zeige SENP1 Antikörper) via de-SUMOylation of protein tyrosine phosphatase 1B (PTP1B (zeige PTPN1 Antikörper)), in IFN-gamma (zeige IFNG Antikörper) signaling, is reported.

  4. In a mouse model of spontaneous osteopenia caused by hyperactivation of STAT1/3 signaling downstream of gp130 (gp130 (zeige LRPPRC Antikörper)(Y757F/Y757F)), STAT1 deletion rescued the osteopenic phenotype, indicating a beneficial effect of promoting STAT3 (zeige STAT3 Antikörper) signaling over STAT1 downstream of gp130 (zeige LRPPRC Antikörper) in this low bone mass condition, and this may have therapeutic value.

  5. this study shows that STAT-1 and STAT-3 (zeige STAT3 Antikörper) interplay to regulate indoleamine 2,3-dioxygenase activity and immunosuppression in response to of IL-27 (zeige IL27 Antikörper) in neonatal macrophages

  6. this study shows that binding motifs for the transcription factors STAT1 and IRF1 (zeige IRF1 Antikörper) are associated with robust and IL-4 (zeige IL4 Antikörper)-resistant responses to IFN-gamma (zeige IFNG Antikörper) in macrophages

  7. Study showed that suppression of STAT3 (zeige STAT3 Antikörper), STAT5 (zeige STAT5A Antikörper), and STAT6 (zeige STAT6 Antikörper) and overexpression of the proapoptotic factor STAT1, which provides p53 (zeige TP53 Antikörper)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (zeige ERBB2 Antikörper) tyrosine kinase receptor (zeige KDR Antikörper) overexpression promotes neuronal survival through activation of STAT-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1

  8. STAT signaling plays a central role during retinal degeneration in the rd10 (zeige PDE6B Antikörper) mouse model.

  9. Donor interleukin-22 (zeige IL22 Antikörper) and host type I interferon (zeige IFNA Antikörper) signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10 (zeige CXCL10 Antikörper).

  10. OGG1 (zeige OGG1 Antikörper) acts as a STAT1 coactivator and has transcriptional activity in the presence of endotoxin

Human Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. the dual regulation of STAT1 by IKKalpha (zeige CHUK Antikörper) in antiviral signaling suggests a role for IKKalpha (zeige CHUK Antikörper) in the fine-tuning of antiviral signaling in response to non-self RNA.

  2. This study demonstrated the first coiled-coil domain mutation of STAT1 as a genetic cause of autosomal-dominant Mendelian susceptibility to mycobacterial diseases

  3. STAT1 suppression by S100A6 (zeige S100A6 Antikörper) may represent a promising therapeutic target to facilitate reendothelialization in damaged vessels.

  4. Our data demonstrate an important connection between mRNA translation and KRAS tumorigenesis under the control of STAT1, which can determine the susceptibility of KRAS tumors to pharmacologic inhibition of mRNA translation initiation.

  5. study demonstrated that miR (zeige MLXIP Antikörper)-9 could inhibit activation of the NLRP3 (zeige NLRP3 Antikörper) inflammasome and attenuate atherosclerosis-related inflammation, likely through the JAK1 (zeige JAK1 Antikörper)/STAT1 signaling pathway. Therefore, miR (zeige MLXIP Antikörper)-9 may serve as a potential therapeutic target for atherosclerosis.

  6. the deubiquitinase USP2a translocates into the nucleus and binds to pY701-STAT1, and inhibits K48-linked ubiquitination and degradation of pY701-STAT1

  7. Demonstrate STAT1-dependent transcriptional activation of TLR8 (zeige TLR8 Antikörper) with estrogen stimulation.

  8. STAT1 binding sites were identified on the putative miR-7 (zeige LILRB1 Antikörper) promoter and stimulation of fibroblasts with the inflammatory cytokine, interferon-gamma (IFN-gamma (zeige IFNG Antikörper)), significantly increased miR-7 (zeige LILRB1 Antikörper) transcriptional activity and resulted in upregulated miR-7 (zeige LILRB1 Antikörper) and loss of EGFR (zeige EGFR Antikörper).

  9. These results demonstrate a novel mechanism by which STAT1 negatively regulates ULK1 (zeige ULK1 Antikörper) expression and autophagy.

  10. In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (zeige GBP1 Antikörper), TLR3 (zeige TLR3 Antikörper), OAS1 (zeige OAS1 Antikörper), EIF2AK2 (zeige EIF2AK2 Antikörper), HLA-E (zeige HLAE Antikörper), IFI6 (zeige IFI6 Antikörper), and STAT1, showed higher expression in the islet core compared with the peri (zeige PLIN1 Antikörper)-islet area containing the surrounding immune cells.

Pig (Porcine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (zeige IFNA Antikörper) response by inducing STAT1 degradation.

  2. this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets

  3. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (zeige JAK3 Antikörper)-STAT1) signaling pathway.

  4. Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 (zeige STAT2 Antikörper) nuclear translocation.

  5. Nsp1beta inhibits interferon-activated (zeige MNDA Antikörper) STAT1/STAT2 (zeige STAT2 Antikörper) signal transduction by inducing karyopherin-alpha1 degradation.

  6. STAT1 is involved in mediating the action of ghrelin (zeige GHRL Antikörper) on ovarian cell functions.

  7. the majority of the STAT1/STAT2 (zeige STAT2 Antikörper)/IRF9 (zeige IRF9 Antikörper) (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked

  8. Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation.

  9. Nitric oxide-dependent increase in caspase-8 (zeige CASP8 Antikörper) mRNA levels is associated with phosphorylation of STAT-1 at Ser (zeige SIGLEC1 Antikörper)-727 and STAT1 binding to the caspase-8 (zeige CASP8 Antikörper) promoter in cultured lung endothelial cells.

  10. Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation.

Cow (Bovine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Interaktionspartner

  1. Report interferon-tau dependent STAT1 regulation of SOCS (zeige CISH Antikörper) genes in bovine endometrium during estrus cycle and embryo implantation.

  2. the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate

  3. results show for the first time that interleukin-6 (zeige IL6 Antikörper) (IL), in the presence of its soluble receptor (zeige IFNAR1 Antikörper) (sIL (zeige STIL Antikörper)-6R), induces activation of JAK1 (zeige JAK1 Antikörper), JAK2 (zeige JAK2 Antikörper), and STAT1/STAT3 (zeige STAT3 Antikörper) proteins in bovine articular chondrocytes

  4. Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein (zeige CSN2 Antikörper) synthesis and fat metabolism.

  5. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2 (zeige STAT2 Antikörper).

STAT1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT1

  • signal transducer and activator of transcription 1, 91kDa (STAT1) Antikörper
  • RIKEN cDNA 2200002D01 gene (2200002D01Rik) Antikörper
  • signal transducer and activator of transcription 1 (Stat1) Antikörper
  • signal transducer and activator of transcription 1, 91kDa (stat1) Antikörper
  • signal transducer and activator of transcription 4 (stat4) Antikörper
  • 2010005J02Rik Antikörper
  • AA408197 Antikörper
  • CANDF7 Antikörper
  • DD6G4-4 Antikörper
  • dZ182H3.3 Antikörper
  • H2RSP Antikörper
  • IMUP Antikörper
  • IMUP-1 Antikörper
  • IMUP-2 Antikörper
  • ISGF-3 Antikörper
  • si:by51f19.1 Antikörper
  • si:by134g18.2 Antikörper
  • si:dz73o4.2 Antikörper
  • si:dz182h3.3 Antikörper
  • si:dz199m19.1 Antikörper
  • STAT Antikörper
  • STAT1 Antikörper
  • STAT4 Antikörper
  • STAT91 Antikörper
  • XStat1 Antikörper

Bezeichner auf Proteinebene für STAT1

signal transducer and activator of transcription 1-alpha/beta , HAI-2 related small protein , signal transducer and activator of transcription-1 , transcription factor ISGF-3 components p91/p84 , signal transducer and activator of transcription 4 , signal transducer and activator of transcription 1 , transcription factor ISGF-3 , activator of transcription , signal transduction

GENE ID SPEZIES
100307049 Ovis aries
72275 Mus musculus
20846 Mus musculus
25124 Rattus norvegicus
6772 Homo sapiens
424044 Gallus gallus
488449 Canis lupus familiaris
396655 Sus scrofa
510814 Bos taurus
398324 Xenopus laevis
100343893 Oryctolagus cuniculus
368519 Danio rerio
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