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SOCS5 Proteine (SOCS5)

Bezeichnung:
Suppressor of Cytokine Signaling 5 Proteine (SOCS5)
Auf www.antikoerper-online.de finden Sie aktuell 5 Suppressor of Cytokine Signaling 5 (SOCS5) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SOCS5 Antikörper (64) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 76 SOCS5 Produkte verfügbar.
Synonyme:
1810018L08Rik, CIS6, Cish5, CISH6, GB18949, mKIAA0671, RGD1564914, SOCS-5, socs5, zgc:153506
alle Proteine anzeigen Gen GeneID UniProt
SOCS5 9655 O75159
SOCS5 56468 O54928
Ratte SOCS5 SOCS5 500616  

Weitere Synonyme anzeigen

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Weitere Proteine zu SOCS5 Interaktionspartnern

Human Suppressor of Cytokine Signaling 5 (SOCS5) Interaktionspartner

  1. This study showed that SOCS5 expression was significantly down-regulated.

  2. Opisthorchis felineus infection diminishes the risk of atopic bronchial asthma associated with the SOCS5 gene polymorphism.

  3. different domains in SOCS5 contribute to two distinct mechanisms for regulation of cytokine and growth factor signaling with JAK1 (zeige JAK1 Proteine) and SHC-1 (zeige SHC1 Proteine)

  4. The rs6737848 SOCS5 polymorphism was significantly associated with asthma in additive model and in dominant model

  5. Exogenous miR (zeige MLXIP Proteine)-9 effectively reduced SOCS5 levels, leading to activated JAK (zeige JAK3 Proteine)-STAT (zeige STAT1 Proteine) pathway, which promoted endothelial cell migration and tumour angiogenesis

  6. Identified is a conserved region of about 70 residues in the N-terminal domains of SOCS4 (zeige SOCS6 Proteine) and 5 that is predicted to be more ordered than the surrounding sequence.

  7. The results may contribute to understanding SOCS5 and SOCS6 (zeige SOCS6 Proteine) expression regulation in various cancer tissues, and show that these two factors may be used for diagnosing cancer.

  8. Up regulation of SOCS1 (zeige SOCS1 Proteine) and SOCS5 expression and down-regulation of SOCS3 (zeige SOCS3 Proteine) and CIS (zeige CISH Proteine) may correlate with the development of a Th1 (zeige TH1L Proteine) mediated immune response in Vogt-Koyanagi-Harada disease.

  9. The reduction in EGFR (zeige EGFR Proteine) levels and EGF (zeige EGF Proteine)-induced signaling in SOCS5-expressing cells requires both the Src (zeige SRC Proteine) homology-2 and SOCS (zeige CISH Proteine) box domains of SOCS5.

  10. Constitutive expression of SOCS5 in transgenic mice results in reduced eosinophil infiltration in allergic conjunctivitis

Mouse (Murine) Suppressor of Cytokine Signaling 5 (SOCS5) Interaktionspartner

  1. have identified a phosphorylation site (Ser211) within the JIR of mSOCS5 and have investigated the role of phosphorylation in modulating JAK (zeige JAK3 Proteine) binding using site-directed mutagenesis.

  2. Identified is a conserved region of about 70 residues in the N-terminal domains of Socs4 (zeige SOCS6 Proteine) and 5 that is predicted to be more ordered than the surrounding sequence.

  3. The effect of Flt3 (zeige FLT3 Proteine)-L on Th17 cells and expression of suppressors of cytokine signaling (SOCS (zeige CISH Proteine)) proteins in the lungs of house dust mite (HDM (zeige HDAC3 Proteine))-sensitized and -challenged mice, was evaluated.

  4. SOCS5 regulates Th1 (zeige HAND1 Proteine)/Th2 cell balance and suppresses IL-4 (zeige IL4 Proteine)

  5. SOCS5-deficient CD4 (zeige CD4 Proteine) T cells showed no abnormalities in Th1 (zeige HAND1 Proteine)/Th2 differentiation and Socs5(-/-) mice showed normal resistance to infection with Leishmania major.

  6. SOCS-5 associated with the EGF-R (zeige EGFR Proteine) complex in an EGF (zeige EGF Proteine)-independent manner

  7. Adoptive transfer of SOCS5Tg-CD4 (zeige CD4 Proteine)+ T cells into T- and B cell-deficient RAG-2 (zeige RAG2 Proteine)(-/-) mice resulted in augmented leukocyte infiltration and increased peritoneal levels of IL-12 (zeige IL12A Proteine), IFN-gamma (zeige IFNG Proteine), and TNF-alpha (zeige TNF Proteine) after cecal ligation and puncture

SOCS5 Protein Überblick

Protein Überblick

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Alternative names and synonyms associated with SOCS5

  • suppressor of cytokine signaling 5 (SOCS5)
  • suppressor of cytokine signaling 5 (socs5)
  • suppressor of cytokine signaling 5 (Socs-5)
  • suppressor of cytokine signaling 5a (socs5a)
  • suppressor of cytokine signaling 5 (Tsp_07018)
  • suppressor of cytokine signaling 5 (Socs5)
  • 1810018L08Rik Protein
  • CIS6 Protein
  • Cish5 Protein
  • CISH6 Protein
  • GB18949 Protein
  • mKIAA0671 Protein
  • RGD1564914 Protein
  • SOCS-5 Protein
  • socs5 Protein
  • zgc:153506 Protein

Bezeichner auf Proteinebene für SOCS5

suppressor of cytokine signaling 5 , suppressor of cytokine signaling 5-like , CIS-6 , cytokine-inducible SH2 protein 6 , cytokine-inducible SH2-containing protein 5 , SOCS-5 , cytokine inducible SH2-containing protein 5

GENE ID SPEZIES
428570 Gallus gallus
459209 Pan troglodytes
474581 Canis lupus familiaris
549598 Xenopus (Silurana) tropicalis
552036 Apis mellifera
714998 Macaca mulatta
768142 Danio rerio
10903311 Trichinella spiralis
100144376 Oryzias latipes
100393834 Callithrix jacchus
100437083 Pongo abelii
100499594 Oncorhynchus mykiss
100580253 Nomascus leucogenys
100190883 Gasterosteus aculeatus
100381168 Xenopus laevis
9655 Homo sapiens
100302367 Sus scrofa
514773 Bos taurus
56468 Mus musculus
500616 Rattus norvegicus
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