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SOCS4 Proteine (SOCS4)

Bezeichnung:
Suppressor of Cytokine Signaling 4 Proteine (SOCS4)
Auf www.antikoerper-online.de finden Sie aktuell 7 Suppressor of Cytokine Signaling 4 (SOCS4) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SOCS4 Antikörper (84) und SOCS4 Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 99 SOCS4 Produkte verfügbar.
Synonyme:
3110032M18Rik, A730004F22Rik, AI427843, AU015727, AU015859, Socs4, socs4a, SOCS6, socs6l, Socs7, wu:fb77f06, zgc:64107
alle Proteine anzeigen Gen GeneID UniProt
Ratte SOCS4 SOCS4 305828  
SOCS4 122809 Q8WXH5
SOCS4 67296 Q91ZA6

Weitere Synonyme anzeigen

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Weitere Proteine zu SOCS4 Interaktionspartnern

Human Suppressor of Cytokine Signaling 4 (SOCS4) Interaktionspartner

  1. Significantly higher levels of suppressor of cytokine signalling (zeige SOCS1 Proteine) proteins SOCS3 (zeige SOCS3 Proteine) and SOCS4 (zeige SOCS6 Proteine) in non-healing chronic wounds compared to the healing/healed chronic wounds were observed at the transcript level.

  2. miR (zeige MLXIP Proteine)-25 promotes the migration and invasion of thyroid cancer cells by directly binding to the 3'-UTR of SOCS4 (zeige SOCS6 Proteine) that leads to the inhibition of SOCS4 (zeige SOCS6 Proteine).

  3. This study showed that increased protein levels of SOCS-4 (zeige SOCS6 Proteine) and SOCS-7 in Alzheimer's disease brains.

  4. SOCS4 (zeige SOCS6 Proteine) is a known inhibitor of epidermal growth factor (EGF (zeige EGF Proteine)) receptor (zeige EGFR Proteine) signalling, and functional studies demonstrated specific upregulation of EGF (zeige EGF Proteine)-dependent immune stimulation in affected family members.

  5. Identified is a conserved region of about 70 residues in the N-terminal domains of SOCS4 (zeige SOCS6 Proteine) and 5 that is predicted to be more ordered than the surrounding sequence.

  6. The expression of SOCS4 (zeige SOCS6 Proteine) seems to be controlled epigenetically and is often weakly expressed in gastric cancer tissue and cell lines. SOCS4 (zeige SOCS6 Proteine) methylation status could be a predictor of gastric cancer prognosis.

  7. Higher mRNA expression levels of SOCS1 (zeige SOCS1 Proteine), 3, 4 and 7 are significantly associated with earlier tumour stage and better clinical outcome in human breast cancer.

  8. These data suggest that miRNAs play an important role in the regulation of cytokine-inducible Src (zeige SRC Proteine) homology and SOCS (zeige CISH Proteine) expression in epithelial cells in response to C. parvum infection.

  9. the expression of SOCS5 (zeige SOCS5 Proteine) and its closest homolog SOCS4 (zeige SOCS6 Proteine) is elevated in cells following treatment with EGF (zeige EGF Proteine), similar to several negative feedback regulators of EGFR (zeige EGFR Proteine) whose expression is up-regulated upon receptor activation.

  10. The structure of the SOCS4 (zeige SOCS6 Proteine)-ElonginC-ElonginB complex reveals a distinct SOCS (zeige CISH Proteine) structural class.

Mouse (Murine) Suppressor of Cytokine Signaling 4 (SOCS4) Interaktionspartner

  1. SOCS4 (zeige SOCS6 Proteine) is a critical regulator of anti-viral immunity.

  2. Identified is a conserved region of about 70 residues in the N-terminal domains of Socs4 (zeige SOCS6 Proteine) and 5 that is predicted to be more ordered than the surrounding sequence.

  3. Negative regulation of the JAK (zeige JAK3 Proteine)/STAT (zeige STAT1 Proteine) pathway is controlled by SOCS4 (zeige SOCS6 Proteine), which target members of negative feedback loops, to suppress follicle growth and development.

  4. Socs4 (zeige SOCS6 Proteine) is a hydroxylation substrate of FIH (zeige CASR Proteine) and promotes vascular differentiation via an oxygen-dependent mechanism.

SOCS4 Protein Überblick

Protein Überblick

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SOCS4

  • suppressor of cytokine signaling 4 (socs4)
  • suppressor of cytokine signaling 6 (SOCS6)
  • suppressor of cytokine signaling 4 (Socs4)
  • suppressor of cytokine signaling 6b (socs6b)
  • suppressor of cytokine signaling 4 (SOCS4)
  • suppressor of cytokine signaling 7 (SOCS7)
  • 3110032M18Rik Protein
  • A730004F22Rik Protein
  • AI427843 Protein
  • AU015727 Protein
  • AU015859 Protein
  • Socs4 Protein
  • socs4a Protein
  • SOCS6 Protein
  • socs6l Protein
  • Socs7 Protein
  • wu:fb77f06 Protein
  • zgc:64107 Protein

Bezeichner auf Proteinebene für SOCS4

suppressor of cytokine signaling 4 , suppressor of cytokine signaling 6 , suppressor of cytokine signaling 4-like , suppressor of cytokine signaling 6 protein , suppressor of cytokine signaling 6, like , suppressor of cytokine signaling 4a , SH2 domain containing SOCS box protein , SOCS-4 , SOCS-7 , suppressor of cytokine signaling 7 , suppressor of cytokine signalling 4

GENE ID SPEZIES
100190867 Gasterosteus aculeatus
100357417 Oryctolagus cuniculus
100386210 Callithrix jacchus
305828 Rattus norvegicus
322950 Danio rerio
423557 Gallus gallus
452919 Pan troglodytes
549828 Xenopus (Silurana) tropicalis
696146 Macaca mulatta
797891 Danio rerio
100144313 Takifugu rubripes
100144385 Oryzias latipes
100514187 Sus scrofa
100590972 Nomascus leucogenys
122809 Homo sapiens
100302366 Sus scrofa
540412 Bos taurus
67296 Mus musculus
100171842 Pongo abelii
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