anti-Ratte (Rattus) SOCS3 Antikörper für Immunohistochemistry (Paraffin-embedded Sections)

Recommended SOCS3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Suppressor of Cytokine Signaling 3 (SOCS3) Antikörper
  • socs3
  • fj09e12
  • zgc:56537
  • wu:fj09e12
  • MGC64393
  • MGC75749
  • xsocs3
  • MGC81248
  • atod4
  • cis3
  • cish3
  • socs-3
  • ssi-3
  • ssi3
  • SOCS3
  • ATOD4
  • CIS3
  • Cish3
  • SOCS-3
  • SSI-3
  • SSI3
  • Cis3
  • EF-10
  • Ef10
  • Ssi3
  • Socs-3
  • Ssi-3
  • suppressor of cytokine signaling 3a
  • suppressor of cytokine signaling 3
  • socs3a
  • socs3
  • SOCS3
  • LOC100227853
  • Socs3
Epitop
AA 180-215
30
21
9
8
4
4
4
3
3
2
2
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
203
70
40
8
8
6
4
4
3
2
2
2
2
1
1
1
Wirt
Kaninchen
124
82
16
Klonalität
Polyklonal
Konjugat
Dieser SOCS3 Antikörper ist unkonjugiert
10
7
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
187
67
56
37
31
25
7
6
5
2
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN670416
315,94 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2628599 IHC (p) WB Rabbit IgG AA 71-85 Anmelden zum Anzeigen Polyclonal
1 ABIN4902293 ELISA IHC (p) Rabbit IgG Anmelden zum Anzeigen Polyclonal

anti-SOCS3 Antikörper für Immunohistochemistry (Paraffin-embedded Sections) mit den meisten Publikationen

  • Human Polyclonal SOCS3 Primary Antibody für ELISA, IF (p) - ABIN670416 (4 Publications): Liu, Ao, Zhou, Cui, Zhou, Yuan, Xiang, Cao, Liu: CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. in Biochemical and biophysical research communications 2010 (PubMed)

Ähnliche anti-SOCS3 Antikörper

Applikation / Reaktivität Ratte (Rattus) Maus
ELISA 18 Antikörper 20 Antikörper
Immunochromatography (IC) 1 Antikörper 1 Antikörper
Immunocytochemistry (ICC) 2 Antikörper 2 Antikörper
Immunofluorescence (IF) 4 Antikörper 4 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 2 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antikörper
Immunohistochemistry (IHC) 17 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antikörper
Immunoprecipitation (IP) 4 Antikörper
Western Blotting (WB) 35 Antikörper
Biochemical Assay (BCA) 2 Antikörper

General

Antigen Suppressor of Cytokine Signaling 3 (SOCS3) Antikörper
Epitop AA 180-215
(30), (21), (9), (8), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(203), (70), (40), (8), (8), (6), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(124), (82), (16)
Klonalität
Polyklonal
Konjugat Dieser SOCS3 Antikörper ist unkonjugiert
(10), (7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(187), (67), (56), (37), (31), (25), (7), (6), (5), (2), (2), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-SOCS3 Antikörper

Target Details SOCS3 Anwendungsinformationen Handhabung ProductDetails: References for anti-SOCS3 antibody (ABIN670416) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Socs 3
Isotyp IgG

Target Details SOCS3

Produktdetails anti-SOCS3 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-SOCS3 antibody (ABIN670416) Bilder zurück nach oben
Antigen
Andere Bezeichnung SOCS3 (SOCS3 Antibody Abstract)
Hintergrund

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp13, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL-6 signaling in vivo (By similarity). Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize IL6ST (By similarity).

Subcellular location: Cytoplasm

Synonyms: CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3, Suppressor of cytokine signaling 3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SOCS3

Molekulargewicht 25kDa
Gen-ID 9021
UniProt O14543
Forschungsgebiet Cancer, Hematopoietic Progenitors, Innate Immunity, Cytokines, Signaling
Pathways JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C

Anwendungsinformationen

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Handhabung ProductDetails: References for anti-SOCS3 antibody (ABIN670416) Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
ELISA 1:500-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen ProductDetails: References for anti-SOCS3 antibody (ABIN670416) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

ProductDetails: References for anti-SOCS3 antibody (ABIN670416)

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Song, Zhang, Li, Li, An, Cheng, Guo: "Dynamic expression of the suppressor of cytokine signaling-3 and cytokines in the cerebral basilar artery of rats with subarachnoid hemorrhage, and the effect of acetylcholine." in: Acta neurochirurgica, Vol. 156, Issue 5, pp. 941-9; discussion 949, 2014

Kou, Hu, Yao, Wang, Shen, Kang, Hong: "Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 62, Issue 3, pp. 283-9, 2013

Zhu, Dai, Han, He, Mo, Chen, Chen, Wu, Yang, Jiang, Chen, Sun, Zhong: "Expression of SOCSs in human prostate cancer and their association in prognosis." in: Molecular and cellular biochemistry, Vol. 381, Issue 1-2, pp. 51-9, 2013

Liu, Ao, Zhou, Cui, Zhou, Yuan, Xiang, Cao, Liu: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." in: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, 2010 Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Rat (Rattus)).

Bilder

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen Handhabung ProductDetails: References for anti-SOCS3 antibody (ABIN670416) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-SOCS3 Antikörper (Suppressor of Cytokine Signaling 3) (AA 180-215) (ABIN670416) Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti SOCS3 Poly...
Immunohistochemistry (IHC) image for anti-SOCS3 Antikörper (Suppressor of Cytokine Signaling 3) (AA 180-215) (ABIN670416) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti SOCS3 Polyclo...