anti-Human SOCS3 Antikörper für Western Blotting

Recommended SOCS3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Suppressor of Cytokine Signaling 3 (SOCS3) Antikörper
  • socs3
  • fj09e12
  • zgc:56537
  • wu:fj09e12
  • MGC64393
  • MGC75749
  • xsocs3
  • MGC81248
  • atod4
  • cis3
  • cish3
  • socs-3
  • ssi-3
  • ssi3
  • SOCS3
  • ATOD4
  • CIS3
  • Cish3
  • SOCS-3
  • SSI-3
  • SSI3
  • Cis3
  • EF-10
  • Ef10
  • Ssi3
  • Socs-3
  • Ssi-3
  • suppressor of cytokine signaling 3a
  • suppressor of cytokine signaling 3 S homeolog
  • suppressor of cytokine signaling 3
  • suppressor of cytokine signaling 3 L homeolog
  • socs3a
  • socs3.S
  • socs3
  • socs3.L
  • SOCS3
  • Socs3
Epitop
AA 2-225
30
21
9
8
4
4
3
3
2
2
2
2
2
1
1
1
Reaktivität
Human, Ratte (Rattus)
202
70
39
8
8
6
4
4
2
2
2
2
2
1
1
1
Wirt
Kaninchen
123
82
16
Klonalität
Polyklonal
Konjugat
Dieser SOCS3 Antikörper ist unkonjugiert
10
7
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
Western Blotting (WB)
186
67
56
37
32
25
7
6
5
2
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN3043437
$ 240.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.2267077 ABIN184566 ELISA WB Goat C-Term Anmelden zum Anzeigen Polyclonal 1
3.2267077 ABIN153119 WB Mouse IgG2b Anmelden zum Anzeigen SO1 1
3.2267077 ABIN4355049 IHC IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal 2
3.2267077 ABIN3044272 IHC (p) WB Rabbit IgG AA 71-85, Middle Region Anmelden zum Anzeigen Polyclonal
3.2267077 ABIN262251 ELISA WB Goat C-Term Anmelden zum Anzeigen Polyclonal 1
3.2267077 ABIN2454618 FACS IF WB Mouse IgG1 Anmelden zum Anzeigen 11C5
3.2267077 ABIN2454684 IHC WB Mouse IgG2b Anmelden zum Anzeigen 15F9
3.2267077 ABIN2454662 FACS IF WB Mouse IgG2a Anmelden zum Anzeigen 6C2
3.2267077 ABIN2454588 FACS WB Mouse IgG1 Anmelden zum Anzeigen 6F3
3.2267077 ABIN2454641 IF WB Mouse IgG1 Anmelden zum Anzeigen 6C12
3.2267077 ABIN2454642 FACS IF IHC WB Mouse IgG2a Anmelden zum Anzeigen 3D3
3.2267077 ABIN2454672 FACS IF IHC WB Mouse IgG2a Anmelden zum Anzeigen 8G3
3.2267077 ABIN2454674 IF WB Mouse IgG2a Anmelden zum Anzeigen 5C2
3.2267077 ABIN2454686 FACS IF IHC WB Mouse IgG1 Anmelden zum Anzeigen 7E10
3.2267077 ABIN2454685 FACS IF WB Mouse IgG2b Anmelden zum Anzeigen 3B8
3.2267077 ABIN2454587 FACS IF IHC WB Mouse IgG2b Anmelden zum Anzeigen 5D4
3.2267077 ABIN94467 WB Mouse IgG2b Anmelden zum Anzeigen SO1 4
3.2267077 ABIN2855919 IHC (p) WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
3.2267077 ABIN1860596 ICC IHC IP WB Rabbit IgG AA 1-225 Anmelden zum Anzeigen Polyclonal
3.2267077 ABIN256461 WB Mouse IgG2b kappa Anmelden zum Anzeigen SOC-25

General

Antigen Suppressor of Cytokine Signaling 3 (SOCS3) Antikörper
Epitop AA 2-225
(30), (21), (9), (8), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Reaktivität Human, Ratte (Rattus)
(202), (70), (39), (8), (8), (6), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Wirt Kaninchen
(123), (82), (16)
Klonalität
Polyklonal
Konjugat Dieser SOCS3 Antikörper ist unkonjugiert
(10), (7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Western Blotting (WB)
(186), (67), (56), (37), (32), (25), (7), (6), (5), (2), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-SOCS3 Antikörper

Target Details SOCS3 Anwendungsinformationen Handhabung Bilder
Verwendungszweck Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 3(SOCS3) detection. Tested with WB in Human,Rat.
Kreuzreaktivität (Details) No cross reactivity with other proteins.
Produktmerkmale Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 3(SOCS3) detection. Tested with WB in Human,Rat.
Gene Name: suppressor of cytokine signaling 3
Protein Name: Suppressor of cytokine signaling 3
Reinigung Immunogen affinity purified.
Immunogen E.coli-derived human SOCS3 recombinant protein (Position: V2-L225). Human SOCS3 shares 96.9% and 95.5% amino acid (aa) sequence identity with mouse and rat SOCS3, respectively.
Isotyp IgG

Target Details SOCS3

Produktdetails anti-SOCS3 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung SOCS3 (SOCS3 Antibody Abstract)
Hintergrund SOCS3 (Suppressor of cytokine signaling 3) is a protein that in humans is encoded by the SOCS3 gene. SOCS3 is transiently expressed by multiple cell lineages within the immune system and functions predominantly as a negative regulator of cytokines that activate the JAK-STAT3 pathway. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. For signaling of IL-6, Epo, GCSF and Leptin, binding of SOCS3 to the respective cytokine receptor has been found to be crucial for the inhibitory function of SOCS3. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Synonyms: ATOD4 antibody|CIS 3 antibody|CIS-3 antibody|CIS3 antibody|Cish3 antibody|Cytokine induced SH2 protein 3 antibody|Cytokine-inducible SH2 protein 3 antibody|E2a Pbx1 target gene in fibroblasts 10 antibody|EF 10 antibody|MGC71791 antibody|SOCS 3 antibody|SOCS-3 antibody|Socs3 antibody|SOCS3_HUMAN antibody|SSI 3 antibody|SSI-3 antibody|SSI3 antibody|STAT induced STAT inhibitor 3 antibody|STAT-induced STAT inhibitor 3 antibody|Suppressor of cytokine signaling 3 antibody
Gen-ID 9021
UniProt O14543
Forschungsgebiet Cancer, Hematopoietic Progenitors, Innate Immunity, Cytokines, Signaling
Pathways JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C

Anwendungsinformationen

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Handhabung Bilder zurück nach oben
Applikationshinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat , The detection limit for SOCS3 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen Bilder zurück nach oben
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Bilder

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 2-225) antibody (ABIN3043437) anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 2-225) antibody