anti-Human SOCS3 Antikörper für Enzyme Immunoassay

Recommended SOCS3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Suppressor of Cytokine Signaling 3 (SOCS3) Antikörper
  • socs3
  • fj09e12
  • zgc:56537
  • wu:fj09e12
  • MGC64393
  • MGC75749
  • xsocs3
  • MGC81248
  • atod4
  • cis3
  • cish3
  • socs-3
  • ssi-3
  • ssi3
  • SOCS3
  • ATOD4
  • CIS3
  • Cish3
  • SOCS-3
  • SSI-3
  • SSI3
  • Cis3
  • EF-10
  • Ef10
  • Ssi3
  • Socs-3
  • Ssi-3
  • suppressor of cytokine signaling 3a
  • suppressor of cytokine signaling 3
  • socs3a
  • socs3
  • SOCS3
  • LOC100227853
  • Socs3
Reaktivität
Human
203
70
40
8
8
6
4
4
2
2
2
2
2
1
1
1
Wirt
Maus
123
83
16
Klonalität
Monoklonal
Konjugat
Dieser SOCS3 Antikörper ist unkonjugiert
10
7
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
187
68
56
37
31
25
7
6
5
2
2
1
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Produktnummer ABIN120754
$ 308.00
Zzgl. Versandkosten $45.00

General

Antigen Suppressor of Cytokine Signaling 3 (SOCS3) Antikörper
Reaktivität Human
(203), (70), (40), (8), (8), (6), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Wirt Maus
(123), (83), (16)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser SOCS3 Antikörper ist unkonjugiert
(10), (7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(187), (68), (56), (37), (31), (25), (7), (6), (5), (2), (2), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-SOCS3 Antikörper

Target Details SOCS3 Anwendungsinformationen Handhabung Bilder
Spezifität This antibody SO1 reacts with SOCS3, an intracellular Cytokine Signaling Inhibitor.
Kreuzreaktivität (Details) Species reactivity (tested):Human
Reinigung Affinity Chromatography on Protein A
Immunogen Full-length SOCS3 protein
Klon 01-11-14
Isotyp IgG2b

Target Details SOCS3

Produktdetails anti-SOCS3 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung SOCS3 / CIS3 (SOCS3 Antibody Abstract)
Hintergrund SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.Synonyms: CIS-3, Cytokine-inducible SH2 protein 3, SOCS-3, SSI-3, SSI3, STAT-induced STAT inhibitor 3, Suppressor of cytokine signaling 3
Gen-ID 9021
UniProt O14543
Pathways JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C

Anwendungsinformationen

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Western blot: Use HeLa human cervix carcinoma cell line as positive control. Sample preparation: Resuspend approx. 50 mil. cells in 1 mLcold lysis buffer (1 % laurylmaltoside in 20 mM Tris/Cl, 100 mM NaCl pH 8.2, 50 mM NaF including protease inhibitor cocktail). Incubate 60 min on ice, centrifuge to remove cell debris. Mix lysate with reducing Laemmli SDS-PAGE sample buffer.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer PBS with 15 mM Sodium Azide as preservative, approx. pH 7.4
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Haltbarkeit 12 months