anti-Human SOCS3 Antikörper für Biochemical Assay

Recommended SOCS3 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Suppressor of Cytokine Signaling 3 (SOCS3) Antikörper
  • socs3
  • fj09e12
  • zgc:56537
  • wu:fj09e12
  • MGC64393
  • MGC75749
  • xsocs3
  • MGC81248
  • atod4
  • cis3
  • cish3
  • socs-3
  • ssi-3
  • ssi3
  • SOCS3
  • ATOD4
  • CIS3
  • Cish3
  • SOCS-3
  • SSI-3
  • SSI3
  • Cis3
  • EF-10
  • Ef10
  • Ssi3
  • Socs-3
  • Ssi-3
  • suppressor of cytokine signaling 3a
  • suppressor of cytokine signaling 3
  • socs3a
  • socs3
  • SOCS3
  • LOC100227853
  • Socs3
Reaktivität
Human, Maus
203
70
41
8
8
6
4
4
3
2
2
2
2
1
1
1
Wirt
Maus
123
83
16
Klonalität
Monoklonal
Konjugat
Dieser SOCS3 Antikörper ist unkonjugiert
10
7
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
Biochemical Assay (BCA)
188
68
56
37
32
25
7
6
5
2
1
1
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2666365
232,94 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2666366 BCA Mouse IgG2b, IgG2b kappa Anmelden zum Anzeigen SOC-25 9

anti-SOCS3 Antikörper für Biochemical Assay mit den meisten Publikationen

  • Human Monoclonal SOCS3 Primary Antibody für BCA - ABIN2666365 (9 Publications): Egwuagu, Yu, Zhang, Mahdi, Kim, Gery: Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)

  • Human Monoclonal SOCS3 Primary Antibody für BCA - ABIN2666366 (9 Publications): Sasaki, Inagaki-Ohara, Yoshida, Yamanaka, Sasaki, Yasukawa, Koromilas, Yoshimura: The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6. in The Journal of biological chemistry 2003 (PubMed)

Ähnliche anti-SOCS3 Antikörper

Applikation / Reaktivität Human Maus
Immunofluorescence (fixed cells) (IF/ICC) 3 Antikörper 2 Antikörper
Western Blotting (WB) 170 Antikörper 65 Antikörper
Immunoprecipitation (IP) 5 Antikörper 4 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 32 Antikörper 5 Antikörper
Immunohistochemistry (IHC) 19 Antikörper 48 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antikörper 1 Antikörper
Immunofluorescence (IF) 37 Antikörper 4 Antikörper
Immunocytochemistry (ICC) 2 Antikörper 4 Antikörper
Immunochromatography (IC) 1 Antikörper

General

Antigen Suppressor of Cytokine Signaling 3 (SOCS3) Antikörper
Reaktivität Human, Maus
(203), (70), (41), (8), (8), (6), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Wirt Maus
(123), (83), (16)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser SOCS3 Antikörper ist unkonjugiert
(10), (7), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Applikation Biochemical Assay (BCA)
(188), (68), (56), (37), (32), (25), (7), (6), (5), (2), (1), (1), (1), (1), (1)
Pubmed 9 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-SOCS3 Antikörper

Target Details SOCS3 Anwendungsinformationen Handhabung ProductDetails: References for anti-SOCS3 antibody (ABIN2666365) Bilder
Produktmerkmale The SOCS3 (suppressor of cytokine signaling-3) protein is a 25 kD cytoplasmic protein that contains a SOCS box and an SH2 domain. SOCS3 has been shown to be involved the negative regulation of cytokine signaling via JAK/STAT pathway. SOCS3 has been shown to inhibit IL-2, IL-3, IL-4, IL-6, erythropoietin, prolactin, and growth hormone. SOCS3 has also been shown to regulate erythropoiesis in the fetal liver. SOCS3 is induced induced by inflammation, erythropoietin, GM-CSF, IL-10, and IFN-γ. SOCS3 can be modified by JAK phophorylation which destabilizes the protein and ubiquitination which targets for destruction by the proteosome. SOCS3 has been shown to interact with the IGF-1 receptor, insulin receptor, gp130 receptor, erythropoietin receptor, leptin receptor, LIF receptor, JAK2, and elongin C. The SOC-25 monoclonal antibody recognizes human and mouse SOCS3 and has been shown to be useful for Western blotting.
Reinigung The antibody was purified by affinity chromatography.
Klon SOC-25
Isotyp IgG2b, IgG2b kappa

Target Details SOCS3

Produktdetails anti-SOCS3 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-SOCS3 antibody (ABIN2666365) Bilder zurück nach oben
Antigen
Andere Bezeichnung SOCS3 (SOCS3 Antibody Abstract)
Forschungsgebiet Cancer, Hematopoietic Progenitors, Innate Immunity, Cytokines, Signaling
Pathways JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C

Anwendungsinformationen

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Handhabung ProductDetails: References for anti-SOCS3 antibody (ABIN2666365) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen ProductDetails: References for anti-SOCS3 antibody (ABIN2666365) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Upon receipt, store undiluted between 2°C and 8°C.

ProductDetails: References for anti-SOCS3 antibody (ABIN2666365)

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Ye, Lowther, Stambas: "Inhibition of reactive oxygen species production ameliorates inflammation induced by influenza A viruses via upregulation of SOCS1 and SOCS3." in: Journal of virology, Vol. 89, Issue 5, pp. 2672-83, 2015

Becerra-Díaz, Terrazas: "Taenia crassiceps infection and its excreted/secreted products inhibit STAT1 activation in response to IFN-γ." in: International journal for parasitology, Vol. 44, Issue 9, pp. 613-23, 2014

Nguyen, Macaubas, Nadeau, Truong, Yoon, Lee, Park, Mellins: "Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways." in: Blood, Vol. 117, Issue 14, pp. 3793-8, 2011

Platten, Youssef, Hur, Ho, Han, Lanz, Phillips, Goldstein, Bhat, Raine, Sobel, Steinman: "Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 35, pp. 14948-53, 2009

Persico, Capasso, Russo, Persico, Crocè, Tiribelli, Iolascon: "Elevated expression and polymorphisms of SOCS3 influence patient response to antiviral therapy in chronic hepatitis C." in: Gut, Vol. 57, Issue 4, pp. 507-15, 2008

Sasaki, Inagaki-Ohara, Yoshida, Yamanaka, Sasaki, Yasukawa, Koromilas, Yoshimura: "The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6." in: The Journal of biological chemistry, Vol. 278, Issue 4, pp. 2432-6, 2003

Egwuagu, Yu, Zhang, Mahdi, Kim, Gery: "Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 7, pp. 3181-7, 2002

Marine, McKay, Wang, Topham, Parganas, Nakajima, Pendeville, Yasukawa, Sasaki, Yoshimura, Ihle: "SOCS3 is essential in the regulation of fetal liver erythropoiesis." in: Cell, Vol. 98, Issue 5, pp. 617-27, 1999

Minamoto, Ikegame, Ueno, Narazaki, Naka, Yamamoto, Matsumoto, Saito, Hosoe, Kishimoto: "Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3." in: Biochemical and biophysical research communications, Vol. 237, Issue 1, pp. 79-83, 1997

Bilder

Produktdetails anti-SOCS3 Antikörper Target Details SOCS3 Anwendungsinformationen Handhabung ProductDetails: References for anti-SOCS3 antibody (ABIN2666365) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-SOCS3 Antikörper (Suppressor of Cytokine Signaling 3) (ABIN2666365) anti-Suppressor of Cytokine Signaling 3 (SOCS3) antibody