anti-Human PTPN11 Antikörper für Immunocytochemistry

Recommended PTPN11 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) Antikörper
  • BPTP3
  • CFC
  • NS1
  • PTP-1D
  • PTP2C
  • SH-PTP2
  • SH-PTP3
  • SHP2
  • 2700084A17Rik
  • AW536184
  • PTP1D
  • SAP-2
  • SHP-2
  • Shp2
  • Syp
  • SYP
  • protein tyrosine phosphatase, non-receptor type 11
  • PTPN11
  • Ptpn11
Epitop
AA 263-329
54
47
25
20
19
17
15
15
15
10
5
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
367
231
202
14
13
13
11
11
10
9
7
4
3
3
2
2
2
1
Wirt
Maus
298
57
19
2
1
Klonalität
Monoklonal
Konjugat
Dieser PTPN11 Antikörper ist unkonjugiert
9
9
9
6
6
5
4
4
4
4
4
4
4
4
4
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
290
125
105
85
52
49
32
21
18
6
3
3
3
2
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN1098117
494,23 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1491299 ELISA FACS ICC IF IHC (p) WB Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN604883 ICC IF IHC (p) WB Rabbit AA 51-206 Anmelden zum Anzeigen Polyclonal
1 ABIN4353396 CyTOF ELISA FACS ICC IF IHC WB Mouse IgG1 Anmelden zum Anzeigen 6D9
1 ABIN4880982 ELISA FACS ICC IHC WB Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN213313 ICC IP Neut WB Rabbit IgG AA 2-216 Anmelden zum Anzeigen Polyclonal
1 ABIN5605825 ELISA FACS ICC IF IHC WB Alexa Fluor 405 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605826 ELISA FACS ICC IF IHC WB Alexa Fluor 488 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605827 ELISA FACS ICC IF IHC WB Alexa Fluor 647 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605828 ELISA FACS ICC IF IHC WB Alexa Fluor 700 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605831 ELISA FACS ICC IF IHC WB DyLight 350 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605830 ELISA ICC IF IHC WB Biotin Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605833 ELISA FACS ICC IF IHC WB DyLight 488 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605832 ELISA FACS ICC IF IHC WB DyLight 405 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605834 ELISA FACS ICC IF IHC WB DyLight 550 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605836 ELISA FACS ICC IF IHC WB DyLight 680 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605838 ELISA FACS ICC IF IHC FITC Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605835 ELISA FACS ICC IF IHC WB DyLight 650 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN5605837 ELISA FACS ICC IF IHC WB DyLight 755 Mouse IgG1 AA 263-329 Anmelden zum Anzeigen 6D9
1 ABIN2989649 ICC IF IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

anti-PTPN11 Antikörper für Immunocytochemistry mit den meisten Publikationen

Ähnliche anti-PTPN11 Antikörper

Applikation / Reaktivität Human
Cytometry by Time of Flight (CyTOF) 1 Antikörper
Dot Blot (DB) 3 Antikörper
ELISA 104 Antikörper
Enzyme Immunoassay (EIA) 3 Antikörper
Flow Cytometry (FACS) 33 Antikörper
Immunochromatography (IC) 5 Antikörper
Immunocytochemistry (ICC) 20 Antikörper
Immunofluorescence (IF) 47 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 3 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 52 Antikörper
Immunohistochemistry (IHC) 126 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 85 Antikörper
Immunoprecipitation (IP) 17 Antikörper
Intracellular Staining (ICS) 2 Antikörper
Neutralization (Neut) 1 Antikörper
Proximity Ligation Assay (PLA) 1 Antikörper

General

Antigen Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) Antikörper
Epitop AA 263-329
(54), (47), (25), (20), (19), (17), (15), (15), (15), (10), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(367), (231), (202), (14), (13), (13), (11), (11), (10), (9), (7), (4), (3), (3), (2), (2), (2), (1)
Wirt Maus
(298), (57), (19), (2), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser PTPN11 Antikörper ist unkonjugiert
(9), (9), (9), (6), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(290), (125), (105), (85), (52), (49), (32), (21), (18), (6), (3), (3), (3), (2), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PTPN11 Antikörper

Target Details PTPN11 Anwendungsinformationen Handhabung ProductDetails: References for anti-PTPN11 antibody (ABIN1098117) Bilder
Reinigung Purified
Immunogen Purified recombinant fragment of human PTPN11 (AA 263-329) expressed in E. Coli.
Klon 6D9
Isotyp IgG1

Target Details PTPN11

Produktdetails anti-PTPN11 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-PTPN11 antibody (ABIN1098117) Bilder zurück nach oben
Antigen
Andere Bezeichnung PTPN11 (PTPN11 Antibody Abstract)
Hintergrund The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
Molekulargewicht 68.4 kDa
Gen-ID 5781
HGNC 5781
Pathways JAK-STAT Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

Anwendungsinformationen

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Handhabung ProductDetails: References for anti-PTPN11 antibody (ABIN1098117) Bilder zurück nach oben
Applikationshinweise ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Anwendungsinformationen ProductDetails: References for anti-PTPN11 antibody (ABIN1098117) Bilder zurück nach oben
Format Liquid
Buffer PBS with 0.05 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage

ProductDetails: References for anti-PTPN11 antibody (ABIN1098117)

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Li, Modi, McDonald, Rossi, Yee, Bhatia: "A critical role for SHP2 in STAT5 activation and growth factor-mediated proliferation, survival, and differentiation of human CD34+ cells." in: Blood, Vol. 118, Issue 6, pp. 1504-15, 2011

Bard-Chapeau, Li, Ding, Zhang, Zhu, Princen, Fang, Han, Bailly-Maitre, Poli, Varki, Wang, Feng: "Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis." in: Cancer cell, Vol. 19, Issue 5, pp. 629-39, 2011

Bilder

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Anwendungsinformationen Handhabung ProductDetails: References for anti-PTPN11 antibody (ABIN1098117) zurück nach oben
Bilder des Herstellers
ELISA image for anti-PTPN11 Antikörper (Protein tyrosine Phosphatase, Non-Receptor Type 11) (AA 263-329) (ABIN1098117) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-PTPN11 Antikörper (Protein tyrosine Phosphatase, Non-Receptor Type 11) (AA 263-329) (ABIN1098117) Figure 2: Flow cytometric analysis of HepG2 cells using PTPN11 mouse mAb (green) and ...
Immunocytochemistry (ICC) image for anti-PTPN11 Antikörper (Protein tyrosine Phosphatase, Non-Receptor Type 11) (AA 263-329) (ABIN1098117) Figure 3: Immunofluorescence analysis of HeLa cells using PTPN11 mouse mAb (green) . ...
Immunohistochemistry (IHC) image for anti-PTPN11 Antikörper (Protein tyrosine Phosphatase, Non-Receptor Type 11) (AA 263-329) (ABIN1098117) Figure 4: Immunohistochemical analysis of paraffin-embedded breast cancer tissues usi...
Immunohistochemistry (IHC) image for anti-PTPN11 Antikörper (Protein tyrosine Phosphatase, Non-Receptor Type 11) (AA 263-329) (ABIN1098117) Figure 5: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues usi...
Western Blotting (WB) image for anti-PTPN11 Antikörper (Protein tyrosine Phosphatase, Non-Receptor Type 11) (AA 263-329) (ABIN1098117) Figure 6: Western blot analysis using PTPN11 mAb against human PTPN11 recombinant pro...