anti-Human PTPN11 Antikörper für Dot Blot

Recommended PTPN11 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) Antikörper
  • BPTP3
  • CFC
  • NS1
  • PTP-1D
  • PTP2C
  • SH-PTP2
  • SH-PTP3
  • SHP2
  • 2700084A17Rik
  • AW536184
  • PTP1D
  • SAP-2
  • SHP-2
  • Shp2
  • Syp
  • SYP
  • protein tyrosine phosphatase, non-receptor type 11
  • PTPN11
  • Ptpn11
Epitop
pTyr584
54
50
30
21
18
17
15
15
15
10
5
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
373
231
202
14
13
13
11
11
10
9
7
4
3
3
2
2
2
1
Wirt
Kaninchen
303
58
19
2
1
Klonalität
Polyklonal
Konjugat
Dieser PTPN11 Antikörper ist unkonjugiert
10
9
9
7
6
5
4
4
4
4
4
4
4
4
4
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Dot Blot (DB), Western Blotting (WB)
291
128
106
85
52
49
36
22
18
6
4
3
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN1881807
$ 324.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
29.101395 ABIN3032397 DB ELISA WB Rabbit Ig Fraction pTyr584 Anmelden zum Anzeigen Polyclonal
1 ABIN2794315 DB WB Rabbit Ig Fraction pTyr584 Anmelden zum Anzeigen Polyclonal

General

Antigen Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) Antikörper
Epitop pTyr584
(54), (50), (30), (21), (18), (17), (15), (15), (15), (10), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(373), (231), (202), (14), (13), (13), (11), (11), (10), (9), (7), (4), (3), (3), (2), (2), (2), (1)
Wirt Kaninchen
(303), (58), (19), (2), (1)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser PTPN11 Antikörper ist unkonjugiert
(10), (9), (9), (7), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Dot Blot (DB), Western Blotting (WB)
(291), (128), (106), (85), (52), (49), (36), (22), (18), (6), (4), (3), (2), (2), (1), (1), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PTPN11 Antikörper

Target Details PTPN11 Anwendungsinformationen Handhabung Referenzen für anti-PTPN11 Antikörper (ABIN1881807) Bilder
Homologie Mouse (Murine),Rat (Rattus)
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This SHP2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y584 of human SHP2.
Klon RB16677

Target Details PTPN11

Produktdetails anti-PTPN11 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PTPN11 Antikörper (ABIN1881807) Bilder zurück nach oben
Antigen
Andere Bezeichnung SHP2 (PTPN11 Antibody Abstract)
Hintergrund SHP2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.

Synonyms: PTPN11, PTP2C, SHPTP2, Tyrosine-protein phosphatase non-receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3
NCBI Accession NP_542168, NP_002825
UniProt Q06124
Forschungsgebiet Neurology
Pathways JAK-STAT Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

Anwendungsinformationen

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Handhabung Referenzen für anti-PTPN11 Antikörper (ABIN1881807) Bilder zurück nach oben
Applikationshinweise WB: 1:2000,DB: 1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Anwendungsinformationen Referenzen für anti-PTPN11 Antikörper (ABIN1881807) Bilder zurück nach oben
Format Liquid
Konzentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Referenzen für anti-PTPN11 Antikörper (ABIN1881807)

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Carver, Piazza, Schuler: "Prolactin enhances insulin-like growth factor I receptor phosphorylation by decreasing its association with the tyrosine phosphatase SHP-2 in MCF-7 breast cancer cells." in: The Journal of biological chemistry, Vol. 285, Issue 11, pp. 8003-12, 2010

Rani, Dhandapany, Nallari, Govindaraj, Singh, Thangaraj: "Mitochondrial DNA haplogroup 'R' is associated with Noonan syndrome of south India." in: Mitochondrion, Vol. 10, Issue 2, pp. 166-73, 2010

Bakken, He, Cannon: "The phosphatase Shp2 is required for signaling by the Kaposi's sarcoma-associated herpesvirus viral GPCR in primary endothelial cells." in: Virology, Vol. 397, Issue 2, pp. 379-88, 2010

Bilder

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Anwendungsinformationen Handhabung Referenzen für anti-PTPN11 Antikörper (ABIN1881807) zurück nach oben
Bilder des Herstellers
Dot Blot (DB) image for anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr584) antibody (ABIN1881807) Dot blot analysis of anti-Phospho-SHP2-pY584 Phospho-specific Pab (ABIN1881807) on ni...
Western Blotting (WB) image for anti-Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) (pTyr584) antibody (ABIN1881807) Dot blot analysis of anti-Phospho-SHP2-pY584 Phospho-specific Pab (ABIN1881807) on ni...