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anti-PIAS3 (PIAS3) Antikörper

Bezeichnung:
anti-Protein Inhibitor of Activated STAT, 3 Antikörper (PIAS3)
Auf www.antikoerper-online.de finden Sie aktuell 61 Protein Inhibitor of Activated STAT, 3 (PIAS3) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PIAS3 Kits (14) und PIAS3 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 90 PIAS3 Produkte verfügbar.
Synonyme:
PIAS3, Pias3l, ZMIZ5

Meistgesuchte Reaktivitäten zu anti-PIAS3 (PIAS3) Antikörper

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anti-Mouse (Murine) PIAS3 Antikörper:

anti-Human PIAS3 Antikörper:

anti-Rat (Rattus) PIAS3 Antikörper:

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Am meisten referenzierte anti-PIAS3 Antikörper

  1. Human Polyclonal PIAS3 Primary Antibody für IHC (p), WB - ABIN1882115 : Nojiri, Joh, Miura, Sakata, Nomura, Nakao, Sobue, Ohara, Asai, Ito: ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3. in Biochemical and biophysical research communications 2004 (PubMed)
    Zeige alle 7 Referenzen für ABIN1882115

  2. Human Polyclonal PIAS3 Primary Antibody für IHC (p), WB - ABIN1882116 : Long, Wang, Matsuura, He, Liu: Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3). in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Zeige alle 7 Referenzen für ABIN1882116

  3. Human Polyclonal PIAS3 Primary Antibody für EIA, WB - ABIN500491 : Shuai, Liu: Regulation of gene-activation pathways by PIAS proteins in the immune system. in Nature reviews. Immunology 2005 (PubMed)
    Zeige alle 2 Referenzen für ABIN500491

  4. Cow (Bovine) Polyclonal PIAS3 Primary Antibody für IHC, WB - ABIN2777574 : Jang, Yoon, Shin, Kim, Lee: PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit. in The Journal of biological chemistry 2004 (PubMed)

  5. Cow (Bovine) Polyclonal PIAS3 Primary Antibody für WB - ABIN2777575 : Roukens, Alloul-Ramdhani, Vertegaal, Anvarian, Balog, Deelder, Hensbergen, Baker: Identification of a new site of sumoylation on Tel (ETV6) uncovers a PIAS-dependent mode of regulating Tel function. in Molecular and cellular biology 2008 (PubMed)

Weitere Antikörper gegen PIAS3 Interaktionspartner

Rhesus Monkey Protein Inhibitor of Activated STAT, 3 (PIAS3) Interaktionspartner

  1. Suppressed Th17 levels correlated with upregulated expression of negative regulatory genes, PIAS3, SHP2, and SOCS3 in CD4 T cells during acute SIV infection.

Mouse (Murine) Protein Inhibitor of Activated STAT, 3 (PIAS3) Interaktionspartner

  1. Data indicate that PIAS3 (protein inhibitor of activated STAT3) interaction modulates EKLF (erythroid Kruppel-like factor (zeige KLF1 Antikörper)) activity in a promoter-dependent and SUMO-independent manner.

  2. PIAS3 suppresses acute graft-versus-host disease by modulating effector T and B cell subsets through inhibition of STAT3 (zeige STAT3 Antikörper) activation.

  3. These data indicate that tachypacing decreased ATBF1 (zeige ZFHX3 Antikörper), leading to enhanced STAT3 (zeige STAT3 Antikörper) DNA-binding activity due to the reduced formation of a binary complex of ATBF1 (zeige ZFHX3 Antikörper) and PIAS3.

  4. MRL/lpr (zeige FAS Antikörper) mice have significantly increased expressions of STAT3 (zeige STAT3 Antikörper) mRNA and protein and decreased expression of mRNA PIAS3 in the kidneys compared with BALB/C mice.

  5. L97A, R99N and R99Q mutations of the PINIT domain (PIAS3(85-272) ) were found to abrogate binding to STAT3 (zeige STAT3 Antikörper), suggesting that these residues were part of a potential binding surface.

  6. Our results indicate that Pias3-dependent SUMOylation of photoreceptor-specific transcription factors is a common mechanism that controls both rod and cone photoreceptor subtype specification, regulating distinct molecular targets in the two cell types

  7. there is an interaction between Zimp7 (zeige ZMIZ2 Antikörper) and PIAS (zeige PIAS1 Antikörper) proteins with higher preference for PIAS3, in androgen receptor (zeige AR Antikörper)-mediated transcription

  8. results indicate a potential role of PIAS3 as transcriptional modulator of TIF2 (zeige NCOA2 Antikörper)-mediated signalling

  9. role in inducing SUMO-1 (zeige SUMO1 Antikörper) modification and transcriptional repression of IRF-1 (zeige IRF1 Antikörper)

  10. identified a novel conserved domain of 180 residues in PIAS (zeige PIAS1 Antikörper) proteins and showed that its 'PINIT' motif as well as other conserved motifs (in the SAP (zeige APCS Antikörper) box and in the RING domain) are independently involved in nuclear retention of PIAS3L

Human Protein Inhibitor of Activated STAT, 3 (PIAS3) Interaktionspartner

  1. SHP2 (zeige PTPN11 Antikörper), SOCS3 (zeige SOCS3 Antikörper) and PIAS3 levels are reduced in medulloblastomas in vivo and in vitro, of which PIAS3 downregulation is more reversely correlated with STAT3 (zeige STAT3 Antikörper) activation. In resveratrol-suppressed medulloblastoma cells with STAT3 (zeige STAT3 Antikörper) downregulation and decreased incidence of STAT3 (zeige STAT3 Antikörper) nuclear translocation, PIAS3 is upregulated, the SHP2 (zeige PTPN11 Antikörper) level remains unchanged and SOCS3 (zeige SOCS3 Antikörper) is downregulated.

  2. The results revealed that although the expression levels of SOCS1 (zeige SOCS1 Antikörper), SOCS3 (zeige SOCS3 Antikörper) and, in particular, pSHP2, tend to decrease in the four types of astrocytomas, PIAS3 downregulation is more negatively correlated with STAT3 (zeige STAT3 Antikörper) activation in the stepwise progress of astrocytomas and would indicate an unfavorable outcome.

  3. 3-Formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating STAT3 (zeige STAT3 Antikörper) signaling through the induction of PIAS3.

  4. PIAS3 may serve as a biomarker for predicting hormone therapy stratification, although it is limited to those breast cancer patients receiving hormone therapy.

  5. Taken together, these results suggest that PIAS3 functions as a positive regulator of HIF-1alpha (zeige HIF1A Antikörper)-mediated transcription by increasing its protein stability.

  6. PIAS3 suppression may be protective against joint destruction in rheumatoid arthritis by regulating synoviocyte migration, invasion, and activation.

  7. PIAS3 primes ATR for checkpoint activation.

  8. PIAS3 expression in squamous cell lung cancer is low and predicts overall survival

  9. Adenovirus E4-ORF3 (zeige ASZ1 Antikörper) targets PIAS3 and together with E1B (zeige BCKDHB Antikörper)-55K remodels SUMO2/SUMO3 Interactions in the nucleus and at virus genome replication domains.

  10. Statistically significant positive correlation has been found between STAT5B (zeige STAT5B Antikörper) and COX-2 (zeige COX2 Antikörper), and significant negative correlation between STAT5B (zeige STAT5B Antikörper) and PIAS3.

PIAS3 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the PIAS

Alternative names and synonyms associated with PIAS3

  • protein inhibitor of activated STAT, 3 (PIAS3) Antikörper
  • protein inhibitor of activated STAT, 3 (pias3) Antikörper
  • protein inhibitor of activated STAT 3 (Pias3) Antikörper
  • protein inhibitor of activated STAT, 3 (Pias3) Antikörper
  • protein inhibitor of activated STAT, 3 (LOC100341019) Antikörper
  • PIAS3 Antikörper
  • Pias3l Antikörper
  • ZMIZ5 Antikörper

Bezeichner auf Proteinebene für PIAS3

protein inhibitor of activated STAT, 3 , E3 SUMO-protein ligase PIAS3-like , e3 SUMO-protein ligase PIAS3-like , E3 SUMO-protein ligase PIAS3 , protein inhibitor of activated STAT protein 3 , zinc finger, MIZ-type containing 5 , KChAP , potassium channel regulatory protein KChAP , potassium channel-associated protein

GENE ID SPEZIES
457223 Pan troglodytes
706775 Macaca mulatta
100144644 Xenopus (Silurana) tropicalis
100401461 Callithrix jacchus
100461795 Pongo abelii
100483204 Ailuropoda melanoleuca
229615 Mus musculus
10401 Homo sapiens
83614 Rattus norvegicus
444507 Xenopus laevis
483160 Canis lupus familiaris
535312 Bos taurus
100511878 Sus scrofa
100341019 Oryctolagus cuniculus
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