PIAS1 Proteine (PIAS1)

Bezeichnung:
Protein Inhibitor of Activated STAT, 1 Proteine (PIAS1)
Auf www.antikoerper-online.de finden Sie aktuell 7 Protein Inhibitor of Activated STAT, 1 (PIAS1) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PIAS1 Antikörper (92) und PIAS1 Kits (25) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 133 PIAS1 Produkte verfügbar.
Synonyme:
2900068C24Rik, ddxbp1, gbp, GU/RH-II, pias, pias1-A, xPAIS1, xPIAS1, zmiz3
alle Proteine anzeigen Gen GeneID UniProt
PIAS1 56469 O88907
PIAS1 8554 O75925
Ratte PIAS1 PIAS1 300772  

Weitere Synonyme anzeigen

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Am meisten referenzierte PIAS1 Proteine

  1. Human PIAS1 Protein expressed in Wheat germ - ABIN1314985 : Chen, Hsu, Ma, Tai, Lee: CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 (PubMed)

Weitere Proteine zu PIAS1 Interaktionspartnern

Mouse (Murine) Protein Inhibitor of Activated STAT, 1 (PIAS1) Interaktionspartner

  1. these results indicate that PIAS1 is a positive regulator of MYC (zeige MYC Proteine).

  2. PIAS1 overexpression exacerbated mutant Huntingtin-associated phenotypes and aberrant protein accumulation

  3. Pias1 expression in primary myoblasts enhances the induction of cardiac muscle genes MyoD (zeige MYOD1 Proteine), Myogenin (zeige MYOG Proteine) and Myomaker. Endothelial cell specific inactivation of Pias1 in vivo impairs yolk sac (zeige ADCY10 Proteine) erythrogenesis, angiogenesis and recapitulates loss of myocardium muscle mass. Pias1 is an essential gene for YS erythropoiesis and vasculogenesis in vivo.

  4. Data suggest overexpression of Pias1 in white adipose tissue (WAT) of obesity/prediabetes improves insulin (zeige INS Proteine) resistance; knockdown of Pias1 in normal WAT leads to insulin (zeige INS Proteine) resistance; Pias1 expression in WAT is down-regulated by c-Jun N-terminal kinase.

  5. Between the E3 SUMO ligase PIAS1 and STAT-3 (zeige STAT3 Proteine).

  6. Knockdown of PIAS1 in astrocytes impairs the accumulation of nuclear STI1 (zeige STIP1 Proteine) in response to irradiation. Moreover, a PIAS1 mutant lacking the STI1 (zeige STIP1 Proteine) binding site is unable to increase STI1 (zeige STIP1 Proteine) nuclear retention.

  7. A novel role of PIAS1 in maintaining the quiescence of dormant hematopoietic stem cells and in the epigenetic repression of the myeloerythroid program.

  8. The present study showed that PIAS1 functions as a SUMO E3 ligase of C/EBPbeta (zeige CEBPB Proteine) to regulate adipogenesis.

  9. Piasy (zeige PIAS4 Proteine) represses the synergistic activation of PITX2 (zeige PITX2 Proteine) with interacting co-factors and Piasy (zeige PIAS4 Proteine) represses Pias1 activation of PITX2 (zeige PITX2 Proteine) transcriptional activity.

  10. MAPK-activated protein kinase-2 limits endothelial inflammation via the PIAS1 S522 phosphorylation-mediated increase in PIAS1 transrepression and SUMO ligase activity.

Human Protein Inhibitor of Activated STAT, 1 (PIAS1) Interaktionspartner

  1. these results indicate that PIAS1 is a positive regulator of MYC (zeige MYC Proteine).

  2. PIAS1 is a prognostic biomarker in breast cancer

  3. PIAS1 is a determinant of poor survival and acts as a positive feedback regulator of AR signaling through enhanced AR stabilization in prostate cancer

  4. PIAS1 overexpression exacerbated mutant Huntingtin-associated phenotypes and aberrant protein accumulation

  5. HBs protein-induced hPIAS1 transcription requires TAL1 (zeige TAL1 Proteine), E47 (zeige TCF3 Proteine), MYOG (zeige MYOG Proteine), NFI (zeige NFIC Proteine), and MAPK (zeige MAPK1 Proteine) signal pathways

  6. identified the SUMO ligase PIAS1 as a constituent PML (zeige PML Proteine)-NB antiviral protein. This finding distinguishes a SUMO ligase that may mediate signaling events important in promyelocytic leukemia (zeige PML Proteine) nuclear body mediated intrinsic immunity.

  7. PIAS1 enhances p300 (zeige EP300 Proteine) recruitment to c-Myb (zeige MYB Proteine)-bound sites through interaction with both proteins. In addition, the E3 activity of PIAS1 enhances further its coactivation

  8. Results show that apocrine breast cancer and prostate cancer cells share a core AR cistrome and target gene signature linked to cancer cell growth, and PIAS1 plays a similar coregulatory role for AR in both cancer cell types.

  9. c-Myc (zeige MYC Proteine) is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 (zeige SENP7 Proteine) and RNF4 (zeige RNF4 Proteine)

  10. Data demonstrate that PIAS1 interacts with TRF2 (zeige TERF2 Proteine) and mediates its sumoylation serving as a molecular switch that controls the level of TRF2 (zeige TERF2 Proteine) at telomeres.

PIAS1 Protein Überblick

Protein Überblick

This gene encodes a member of the mammalian PIAS

Alternative names and synonyms associated with PIAS1

  • protein inhibitor of activated STAT, 1 (LOC100232805)
  • protein inhibitor of activated STAT 1 (Pias1)
  • protein inhibitor of activated STAT, 1 (PIAS1)
  • protein inhibitor of activated STAT, 1 (Pias1)
  • protein inhibitor of activated STAT, 1 (pias1)
  • 2900068C24Rik Protein
  • ddxbp1 Protein
  • gbp Protein
  • GU/RH-II Protein
  • pias Protein
  • pias1-A Protein
  • xPAIS1 Protein
  • xPIAS1 Protein
  • zmiz3 Protein

Bezeichner auf Proteinebene für PIAS1

protein inhibitor of activated STAT, 1 , DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1 , DEAD/H box-binding protein 1 , E3 SUMO-protein ligase PIAS1 , protein inhibitor of activated STAT protein 1 , AR interacting protein , RNA helicase II-binding protein , gu-binding protein , protein inhibitor of activated STAT-1 , zinc finger, MIZ-type containing 3 , SUMO E3 ligase

GENE ID SPEZIES
100232805 Taeniopygia guttata
56469 Mus musculus
8554 Homo sapiens
300772 Rattus norvegicus
564496 Danio rerio
373715 Xenopus laevis
427514 Gallus gallus
478350 Canis lupus familiaris
509231 Bos taurus
100339509 Oryctolagus cuniculus
100729878 Cavia porcellus
100519005 Sus scrofa
101104493 Ovis aries
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