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Human Leptin ELISA Kit für Sandwich ELISA - ABIN625035
Jiménez-Pavón, Ortega, Artero, Labayen, Vicente-Rodriguez, Huybrechts, Moreno, Manios, Béghin, Polito, De Henauw, Sjöström, Castillo, González-Gross, Ruiz: Physical activity, fitness, and serum leptin concentrations in adolescents. in The Journal of pediatrics 2012
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Mouse (Murine) Leptin ELISA Kit für Sandwich ELISA - ABIN625156
Jiao, Feng, Ma, Nie, Paul, Li, Xu: Constitutive Activation of IKKβ in Adipose Tissue Prevents Diet-Induced Obesity in Mice. in Endocrinology 2011
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Rat (Rattus) Leptin ELISA Kit für Sandwich ELISA - ABIN625206
Zhang, Wang, Long, Wang, Li, Gao, Tian: Alteration of sweet taste in high-fat diet induced obese rats after 4 weeks treatment with exenatide. in Peptides 2013
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Human Leptin ELISA Kit für Sandwich ELISA - ABIN411318
Masuzaki, Ogawa, Sagawa, Hosoda, Matsumoto, Mise, Nishimura, Yoshimasa, Tanaka, Mori, Nakao: Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. in Nature medicine 1997
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Pig (Porcine) Leptin ELISA Kit für Sandwich ELISA - ABIN415853
Walsh, Sweeney, Bahar, ODoherty: Multi-functional roles of chitosan as a potential protective agent against obesity. in PLoS ONE 2013
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Rat (Rattus) Leptin ELISA Kit für Sandwich ELISA - ABIN416359
Zhang, Liu, Wang, Sun, Su, Zhang, Li, Yang: Puerarin improves insulin resistance and modulates adipokine expression in rats fed a high-fat diet. in European journal of pharmacology 2010
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Human Leptin ELISA Kit für Sandwich ELISA - ABIN612724
Karakus, Gelisgen, Topcuoglu, Guralp, Topcuoglu, Simsek, Uludag, Uzun: The effects of 17β-estradiol plus drospirenone on anthropometric and biochemical measures of adiposity in menopausal women. in Archives of gynecology and obstetrics 2012
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Rat (Rattus) Leptin ELISA Kit für Sandwich ELISA - ABIN365192
Kumar, Kaur: Intermittent fasting dietary restriction regimen negatively influences reproduction in young rats: a study of hypothalamo-hypophysial-gonadal axis. in PLoS ONE 2013
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Cow (Bovine) Leptin ELISA Kit für Competition ELISA - ABIN364601
Osorio, Trevisi, Ballou, Bertoni, Drackley, Loor: Effect of the level of maternal energy intake prepartum on immunometabolic markers, polymorphonuclear leukocyte function, and neutrophil gene network expression in neonatal Holstein heifer calves. in Journal of dairy science 2013
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Mouse (Murine) Leptin ELISA Kit für Sandwich ELISA - ABIN365180
Olea, Ribeiro, Gallego-Martin, Yubero, Rigual, Masa, Obeso, Conde, Gonzalez: The Carotid Body Does Not Mediate the Acute Ventilatory Effects of Leptin. in Advances in experimental medicine and biology 2015
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These results confirm and extend the previous evidence that LEP has a general and important role in the response of mammalian cells to irradiation.
leptin is involved in the proliferation and activation of microglia, which in turn enhances the development of neuropathic pain after avulsion of the cervical roots.
Suggest that intact endothelial leptin signaling limits neointima formation and that obesity represents a state of endothelial leptin resistance.
these studies demonstrate marked differences in the acute insulin (zeige INS ELISA Kits)-independent effects by which leptin reverses fasting hyperglycemia and ketoacidosis in a rodent model of DKA versus the chronic pleotropic effects by which leptin reverses hyperglycemia in a non-DKA rodent model of T1D.
High fat diet attenuates leptin signaling throughout the brain, but some brain regions maintain their ability to sense leptin. Weight loss restores leptin sensing to some degree in most (but not all) brain regions, while other brain regions display hypersensitivity to leptin following weight loss
CNS-specific Tak1 (zeige NR2C2 ELISA Kits) deletion prevented ER-stress-induced hypothalamic leptin resistance and hyperphagic obesity under a high-fat diet (HFD). Thus, TAK1 (zeige NR2C2 ELISA Kits) is a crucial regulator of ER stress in vivo, which could be a target for alleviation of ER stress and its associated disease conditions.
These data further implicate IL-6 (zeige IL6 ELISA Kits) in fatty liver disease modulation in the context of DIO, and indicate that continuous stimulation with IL-6 (zeige IL6 ELISA Kits) attenuates the IL-6 (zeige IL6 ELISA Kits)-receptor response, which is associated with high serum levels of leptin.
these data unmasked a role for mitochondrial fission in leptin sensitivity and glucose sensing of POMC (zeige POMC ELISA Kits) neurons.
Obesity and leptin deficiency substantially decreased morphine metabolism and clearance.
These findings suggest that by impairing the testicular LEP-JAK (zeige JAK3 ELISA Kits)-STAT (zeige STAT1 ELISA Kits) pathway, early-stage obesity inhibits the biosynthesis of testosterone and sexual development and reduces male reproductive potential. Long-term moderate and high-volume exercise can effectively reduce body fat and improve obesity-induced abnormalities in testicular leptin signal transduction, whereas only moderate-volume exercise can reverse the negativ
High leptin/adiponectin (zeige ADIPOQ ELISA Kits) ratio in pregnancy, particularly in those with gestational diabetes, is associated with an unfavorable CVD risk profile during follow-up.
leptin-adiponectin (zeige ADIPOQ ELISA Kits) imbalance, as reflected by an increase in leptin/adiponectin (zeige ADIPOQ ELISA Kits) ratio, was found to be a better diagnostic biomarker for MS than leptin or adiponectin (zeige ADIPOQ ELISA Kits) alone.
Leptin knockdown suppressed MUC5AC production and secretion induced by IL-13 (zeige IL13 ELISA Kits) in human bronchial epithelial cells.
Leptin levels increase significantly within 3 months of fetal pancreatic stem cell transplant in patients with type 1 diabetes mellitus.
High leptin expression is associated with lymph node metastasis in breast cancer.
High leptin serum level is associated with lung cancer.
IL-23 (zeige IL23A ELISA Kits) R (rs7517847) and LEP (rs7799039) polymorphisms were associated with an increased risk but not affecting the clinical presentation of HCC (zeige FAM126A ELISA Kits) among Egyptian patients
the modulation of LEP and IGF-1 serum levels by LEP gene polymorphism at rs7799039 loci; evidence for Growth hormone deficiency pathogenesis
Leptin in autoimmune diseases has gradually become clear. It has been shown that leptin acts as an exacerbating factor in many autoimmune diseases and it is suggested that inhibition of leptin signal may be a novel therapeutic method for autoimmune diseases.
Leptin also significantly increased cAMP levels, cAMP response element (CRE) activation, and CREB (zeige CREB1 ELISA Kits) phosphorylation.
The lack of effect of heat stress on the expression of leptin suggests that this peptide may not be involved in the reduction of feed intake of HS acclimated pigs.
A high variability of the LEP was detected in the different analysed populations providing new data for the existence of two domestication centres in Asia.
The presence of leptin and ObR (zeige LEPR ELISA Kits)-b varies across parities and is more intense in the uterus, ovaries and hypothalamus of females that were cycling before culling than in those having cystic ovaries.
Studied 3'UTR (zeige UTS2R ELISA Kits) leptin polymorphism regulatory sequences' affect on gene expression and their association with production traits.
These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs.
Data showing changes in expression patterns of LEP/LEPR (zeige LEPR ELISA Kits) in endometrium/chorioallantoic membrane during placentation/fetal development suggest role for LEP/LEPR (zeige LEPR ELISA Kits) complex at early stages of pregnancy, possibly affecting the attachment process.
Another funning discovery is ob-Rb (zeige LEPR ELISA Kits) mRNA in porcine endometrium was mainly negative-regulated by leptin
Characterization of a distinctive pattern of periovulatory leptin secretion and its relationship with ovulation rate and luteal function in swine with obesity/leptin resistance
Leptin and leptin receptor (zeige LEPR ELISA Kits) are expressed in porcine luteal cells, and there is a modulatory effect of LH, estradiol (E) and progesterone (P) on leptin mRNA expression as well as E and P on leptin secretion by those cells obtained in early pregnancy.
The present study aimed to determine the effects of breed and sex on growth patterns and metabolic features of advanced-pregnancy foetuses from lean and obese/leptin resistant swine.
Consistent with this, leptin enhanced GnRH (zeige GNRH1 ELISA Kits)-induced secretion of LH measured by ELISA. We suggest that leptin enhances membrane expression of voltage-gated Na(+) and Ca(2 (zeige CA2 ELISA Kits)+) channels, which results in a modulation of the action potential properties and an increase in hormone release from gonadotropes.
The effects of a single nucleotide polymorphism of leptin on weight gain and body composition are reported.
A leptin SNP (LEPg.978) was significantly associated with a weight at one year.
The results of this study suggest that leptin physiology could be a candidate for mechanisms that contribute to feed intake and feed efficiency variation in beef cattle.
Leptin concentrations could be a useful physiological marker for growth and feed efficiency of finishing beef cattle.
Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin-NPY (zeige NPY ELISA Kits) and insulin (zeige INS ELISA Kits) signaling pathways.
Leptin R25C genotype impacted most traits associated with fatness.
The absence of A80V polymorphism (C --> T at position 95691973 bp of leptin gene) has been established in the genotypes of Ayrshire cattle as compared to Holstein cattle.
Data indicate that increased body weight gain during juvenile development accelerates sexual maturation in heifers, coincident with reciprocal changes in circulating concentrations of leptin and hypothalamic neuropeptide Y (NPY (zeige NPY ELISA Kits)) release.
SNP LEP significantly affected milk, protein and fat yield (P<0.05), and age at first calving (P<0.01) in analyzed population of cows. SNP LEPR (zeige LEPR ELISA Kits)/T945M affected significantly calving interval (P<0.01) only
polymorphisms of the LEP gene might be important genetic factors influencing growth traits, and these genetic markers may be useful for future marker-assisted selection programs in goat breeding and production
study suggests that increased CSF (zeige CSF2 ELISA Kits) leptin, likely from blood-brain barrier breakdown, combined with elevated serum GH and IGF-1 (zeige IGF1 ELISA Kits) after traumatic brain injury, leads to accelerated fracture healing
We conclude that offspring from mothers consuming a high fat diet exhibit an adverse cardiovascular profile in adulthood because of altered central hypothalamic sensitivity to leptin and ghrelin (zeige GHRL ELISA Kits).
Niacin Reduces serum level and adipose mRNA expression of leptin and up-regulates PPARgamma (zeige PPARG ELISA Kits) and CD36 (zeige CD36 ELISA Kits) mRNA expression in hypercholesterolemic rabbits.
Positive correlations were found between leptin and total lipids, triglycerides, VLDLs, Total-Chol, and LDLs.
Leptin metabolism in obese ponies following a return to free feeding after a period of food deprivation is reported.
Plasma levels of leptin (as well as glucose, insulin, and growth hormone) are highly correlated with the duration of winter anovulatory phase.
GHRL (zeige GHRL ELISA Kits), LEP, ADIP (zeige SSX2IP ELISA Kits), INS (zeige INS ELISA Kits) and CORT (zeige CORT ELISA Kits) concentrations were measured using radioimmunoassay
positive correlation between leptin and estradiol led us to suggest that leptin hormone plays an important role in ovulation of the first postpartum estrus in mares
The effects of exogenous human kisspeptin-10 (KP10) were studied on three important adipokines, namely, adiponectin (zeige ADIPOQ ELISA Kits), leptin, and resistin (zeige RETN ELISA Kits) in a set of four chair-restraint habituated intact adult male rhesus monkeys.
results do not support a role for reduced leptin secretion in anovulation induced by dietary restriction
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
, leptin (murine obesity homolog)
, leptin (obesity homolog, mouse)
, obese protein
, obese, mouse, homolog of