anti-JAK2 (JAK2) Antikörper

Bezeichnung:
anti-Janus Kinase 2 Antikörper (JAK2)
Auf www.antikoerper-online.de finden Sie aktuell 280 Janus Kinase 2 (JAK2) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen JAK2 Kits (30) und JAK2 Proteine (25) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 349 JAK2 Produkte verfügbar.
Synonyme:
AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

Meistgesuchte Reaktivitäten zu anti-JAK2 (JAK2) Antikörper

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anti-Human JAK2 Antikörper:

anti-Mouse (Murine) JAK2 Antikörper:

anti-Rat (Rattus) JAK2 Antikörper:

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Am meisten referenzierte anti-JAK2 Antikörper

  1. Human Polyclonal JAK2 Primary Antibody für WB - ABIN265197 : Manning, DiSalvo, Stull: Protein phosphorylation: quantitative analysis in vivo and in intact cell systems. in Molecular and cellular endocrinology 1980 (PubMed)
    Zeige alle 12 Referenzen für 265197

  2. Human Polyclonal JAK2 Primary Antibody für FACS, IF - ABIN387982 : Joos, Granzow, Holtgreve-Grez, Siebert, Harder, Martín-Subero, Wolf, Adamowicz, Barth, Lichter, Jauch: Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Zeige alle 5 Referenzen für 387982

  3. Human Polyclonal JAK2 Primary Antibody für IF, ELISA - ABIN1532352 : Dalal, Arpaia, Dadi, Kulkarni, Squire, Roifman: Cloning and characterization of the human homolog of mouse Jak2. in Blood 1998 (PubMed)
    Zeige alle 2 Referenzen für 1532352

  4. Human Polyclonal JAK2 Primary Antibody für IHC, ELISA - ABIN1532914 : Peeters, Raynaud, Cools, Wlodarska, Grosgeorge, Philip, Monpoux, Van Rompaey, Baens, Van den Berghe, Marynen: Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. in Blood 1997 (PubMed)
    Zeige alle 2 Referenzen für 1532914

  5. Mouse (Murine) Polyclonal JAK2 Primary Antibody für IHC (p), WB - ABIN658412 : Qian, Lin, Yao, Chen, Xiao, Ji, Li, Yang, Qian: Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Zeige alle 2 Referenzen für 658412

  6. Human Polyclonal JAK2 Primary Antibody für EIA, WB - ABIN356677 : Kanda, Watanabe: Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. in Endocrinology 2007 (PubMed)

Weitere Antikörper gegen JAK2 Interaktionspartner

Zebrafish Janus Kinase 2 (JAK2) Interaktionspartner

  1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma (zeige IFNG Antikörper) signal.

Human Janus Kinase 2 (JAK2) Interaktionspartner

  1. Molecular interactions of EphA4 (zeige EPHA4 Antikörper), growth hormone receptor (zeige GHR Antikörper), Jak2, and STAT5B (zeige STAT5B Antikörper) have been described.

  2. Peritoneal membrane dysfunction in long-term peritoneal dialysis patients may result from IL-6 (zeige IL6 Antikörper) promotion of epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 (zeige STAT3 Antikörper) signaling pathway.

  3. Mutation inactivating JAK2 gene is associated with Breast Cancer Metastasis.

  4. mechanical load upregulates expression of Runx2 (zeige RUNX2 Antikörper) gene via potentiation of PC1 (zeige PCSK1 Antikörper)-JAK2/STAT3 (zeige STAT3 Antikörper) signaling axis, culminating to possibly control osteoblastic differentiation and ultimately bone formation.

  5. blocking the ERRalpha (zeige ESRRA Antikörper)-controlled mitochondrial program largely inhibits the PLA2R1 (zeige PLA2R1 Antikörper)-induced tumor-suppressive response. Together, our data document ERRalpha (zeige ESRRA Antikörper) and its mitochondrial program as downstream effectors of the PLA2R1 (zeige PLA2R1 Antikörper)-JAK2 pathway leading to oncosuppression.

  6. JAK2 was overexpressed in Epstein Barr virus-associated gastric adenocarcinoma.

  7. As marrow histology in this murine model of myeloproliferation reveals a preferentially perivascular localization of JAK2(V617F)-mutant megakaryocytes and an increased marrow sinusoid vascular density

  8. mutated FLT3 (zeige FLT3 Antikörper)-ITD and JAK2 augment reactive oxygen species production and homologous recombination, shifting the cellular milieu toward illegitimate recombination events.

  9. Germ line JAK2 mutations E846D and R1063H are associated with hereditary erythrocytosis with megakaryocytic atypia.

  10. Data suggest that ruxolitinib treatment for up to 4 years provides progressive reductions in Janus kinase 2 (JAK2) p.V617F allele burden in patients with polycythemia vera (zeige IGF2BP3 Antikörper) (PV).

Mouse (Murine) Janus Kinase 2 (JAK2) Interaktionspartner

  1. Study shows that Jak2 with V617F mutation induces murine model for myeloproliferative neoplasm.

  2. results suggest that loss of Ezh2 (zeige EZH2 Antikörper) cooperates with Jak2V617F in the development of myelofibrosis in Jak2V617F

  3. JAK2-V617F-expressing mice treated with an Ezh2 (zeige EZH2 Antikörper) inhibitor showed higher platelet counts than vehicle controls. Our data support the proposed tumor suppressor function of EZH2 (zeige EZH2 Antikörper)

  4. findings demonstrate that clinically relevant doses of the JAK1 (zeige JAK1 Antikörper)/2 inhibitor ruxolitinib suppresses the harmful consequences of macrophage overactivation characterizing Hemophagocytic lymphohistiocytosis in 2 murine models.

  5. JAK2 has a role in hepatocarcinogenesis through regulating critical inflammatory pathways

  6. Data show that CUZD1 (zeige CUZD1 Antikörper) interacts with a complex containing JAK1 (zeige JAK1 Antikörper)/JAK2 and STAT5 (zeige STAT5A Antikörper), downstream transducers of prolactin (zeige PRL Antikörper) signaling in the mammary gland.

  7. The results showed that AG490 inhibited (p)-JAK2 and RANKL (zeige TNFSF11 Antikörper) expression.

  8. these results have revealed that phosphorylation of Tyr (zeige TYR Antikörper)-343, Tyr (zeige TYR Antikörper)-460, and Tyr (zeige TYR Antikörper)-464 in EpoR (zeige EPOR Antikörper) underlies JAK2 V617F mutant-induced tumorigenesis.

  9. this study shows that ampelopsin reduces inflammatory response of microglial cells through inhibition of JAK2-STAT3 (zeige STAT3 Antikörper) signaling

  10. At the molecular level, administration of liraglutide induced the expression of PDX-1 (zeige PDX1 Antikörper), MafA (zeige MAFA Antikörper), p-JAK2 and p-Stat3 (zeige STAT3 Antikörper) in high-fat diet-induced diabetes model to relatively normal levels.

Pig (Porcine) Janus Kinase 2 (JAK2) Interaktionspartner

  1. nitration of JAK2 may act as an inhibitory counterpart to phosphorylation activation, reflecting a very localized break on the progression of GH signal transduction processes spanning JAK (zeige JAK3 Antikörper)-STAT (zeige STAT1 Antikörper)-AKT (zeige AKT1 Antikörper) interactions

Cow (Bovine) Janus Kinase 2 (JAK2) Interaktionspartner

  1. Janus kinase 2 (JAK2) gene polymorphism is a potential marker for milk production traits in cattle

  2. Results indicate that SNPs in STAT5A (zeige STAT5A Antikörper) and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2-STAT5 (zeige STAT5A Antikörper) and mTOR (zeige FRAP1 Antikörper) signaling pathways.

  4. SNPs in JAK2 and STAT5B (zeige STAT5B Antikörper) are associated with mastitis susceptibility in Chinese Holstein cattle

  5. Localized changes in the state of nitration of regulatory phosphorylation domains of JAK2 in caveoLAE during inflammation suggest a unique mechanism through which discrete signal transduction switching might occur in the liver

JAK2 Antigen-Profil

Beschreibung des Gens

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Alternative names and synonyms associated with JAK2

  • Janus kinase 2b (jak2b) Antikörper
  • Janus kinase 2 (JAK2) Antikörper
  • Janus kinase 2 (Jak2) Antikörper
  • tyrosine-protein kinase JAK2-like (LOC100051487) Antikörper
  • AI504024 Antikörper
  • C81284 Antikörper
  • Fd17 Antikörper
  • JAK-2 Antikörper
  • jak2 Antikörper
  • JAK2bCA Antikörper
  • JTK10 Antikörper
  • THCYT3 Antikörper

Bezeichner auf Proteinebene für anti-Janus Kinase 2 (JAK2) Antikörper

Jak2b kinase , PTK JAK2b , protein tyrosine kinase JAK2b , tyrosine-protein kinase JAK2 , JAK-2 , Janus kinase 2 (a protein tyrosine kinase) , tyrosine kinase

GENE ID SPEZIES
30298 Danio rerio
3717 Homo sapiens
16452 Mus musculus
24514 Rattus norvegicus
374199 Gallus gallus
484185 Canis lupus familiaris
397201 Sus scrofa
525246 Bos taurus
464979 Pan troglodytes
100172517 Pongo abelii
100051487 Equus caballus
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