IL2R Proteine (CD132)

IL-2R Proteine (CD132)
Auf finden Sie aktuell 1 IL-2R (CD132) Proteine von 1 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IL2R Kits (3) und IL2R Antikörper (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 5 IL2R Produkte verfügbar.
alle Proteine anzeigen Gen GeneID UniProt
CD132 3559 P01589

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Human IL-2R (CD132) Interaktionspartner

  1. Through GWAS, we found that emotion dysregulation is associated at genome-wide level significance in a sex-specific manner, with a SNP in IL2RA (zeige IL2RA Proteine) in men.

  2. it has been shown that CD25 (zeige IL2RA Proteine) serves as a negative growth regulator of Chronic myeloid leukemia (zeige BCL11A Proteine) leukemic stem cells.

  3. study provides evidence that membrane-coated microvesicles released by apoptotic neutrophils suppress a subset of resting Th cells by downregulating IL-2 (zeige IL2 Proteine) and IL-2R expression

  4. In T1D, low IL-2 (zeige IL2 Proteine) responsiveness was most pronounced in memory T effector cells. Reduced IL-2 (zeige IL2 Proteine) responses in memory T effector cells were not rescued by resting, remained lower after activation and proliferation, and were absent in type 2 diabetes.

  5. Decidual stromal cells affect IL-2 (zeige IL2 Proteine) production and IL-2R expression and signaling.

  6. The single nucleotide variant rs12722489 determines differential ERalpha (zeige ESR1 Proteine) binding and enhancer properties of an IL2RA (zeige IL2RA Proteine) intronic region.

  7. CDK6 (zeige CDK6 Proteine)-mediated suppression of CD25 (zeige IL2RA Proteine) is required for initiation of T-ALL by activated Notch1 (zeige NOTCH1 Proteine)

  8. CD4 (zeige CD4 Proteine)(+) CD25 (zeige IL2RA Proteine)(+) GARP (zeige CNGB1 Proteine)(+) Treg cells are defective in dilated cardiomyopathy patients and GARP (zeige CNGB1 Proteine) seems to be a better molecular definition of the regulatory phenotype.

  9. Studies indicate many potential uses of soluble interleukin-2 (zeige IL2 Proteine) receptor measurement in the diagnosis and treatment of hemophagocytic syndromes.

  10. Data suggest that differential methylation of the IL2RA (zeige IL2RA Proteine) promoter in T cells could be an important pathogenic mechanism in multiple sclerosis.

IL2R (CD132) Protein Überblick

Protein Überblick

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Alternative names and synonyms associated with IL2R (CD132)

  • interleukin 2 receptor, alpha (IL2RA)
  • CD25 Protein
  • IDDM10 Protein
  • IL2R Protein
  • TCGFR Protein

Bezeichner auf Proteinebene für IL-2R Proteine (CD132)

IL-2 receptor subunit alpha , IL-2-RA , IL-2R subunit alpha , IL2-RA , TAC antigen , interleukin-2 receptor subunit alpha , p55

3559 Homo sapiens
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