anti-Human HTR1D Antikörper für Immunohistochemistry

Recommended HTR1D Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Serotonin Receptor 1D (HTR1D) Antikörper
  • AI853647
  • Gpcr14
  • Htr1db
  • 5-HT1D
  • HT1DA
  • HTR1DA
  • HTRL
  • RDC4
  • 5HT1D
  • 5-HT-1D
  • 5-hydroxytryptamine (serotonin) receptor 1D
  • 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
  • Htr1d
  • HTR1D
Epitop
AA 1-18
14
10
7
6
5
4
2
2
2
2
2
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
35
30
17
3
2
2
Wirt
Kaninchen
54
Klonalität
Polyklonal
Konjugat
Dieser HTR1D Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
31
23
14
2
2
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2470118
$ 515.63
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2193086 IHC Rabbit Anmelden zum Anzeigen Polyclonal

General

Antigen Serotonin Receptor 1D (HTR1D) Antikörper
Epitop AA 1-18
(14), (10), (7), (6), (5), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(35), (30), (17), (3), (2), (2)
Wirt Kaninchen
(54)
Klonalität
Polyklonal
Konjugat Dieser HTR1D Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(31), (23), (14), (2), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-HTR1D Antikörper

Target Details HTR1D Anwendungsinformationen Handhabung Bilder
Reinigung Protein G Column
Immunogen HTR1D antibody was raised against amino acids 1 - 18 of HTR1D (Rat).
Isotyp IgG

Target Details HTR1D

Produktdetails anti-HTR1D Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung HTR1D (HTR1D Antibody Abstract)
Hintergrund Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems (1,2). The 5-HT1D (formerly known as 5-HT1Da) receptor has 63 % overall structural homology with the 5-HT1B receptor and a 77 % amino acid sequence homology in the seven transmembrane domains. In situ hybridization studies have detected highest level of mRNA in primary olfactory cortex, accumbens nucleus, caudate putamen, lateral mammilary nucleus and medial vestibular nucleus. The presence of relatively high levels of 5-HT1D mRNA in the locus coeruleus suggest that, when expressed on nerve terminals, this receptor could modulate the release of catecholamines. The 5-HT1D receptor may function as an autoreceptor. Like 5-HT1B receptors, 5-HT1D receptors also appear to act as heteroreceptors. Acting on the 5-HT1D receptors, 5-HT appears to inhibit release of glutamate from rat cerebellar synaptosomes and acetylcholine from guinea pig hippocampal synaptosomes. It has been suggested that neurogenic inflammation and nociceptive activity within trigemino- vascular afferents. Endothelium-dependent relaxation in the pig coronary artery has been claimed to be mediated by 5-HT1D receptors. Like other members of the 5-HT1 family, 5-HT1D receptors are negatively coupled to adenylate cyclase.
Gen-ID 3352
UniProt P28221
Pathways JAK-STAT Signalweg

Anwendungsinformationen

Produktdetails anti-HTR1D Antikörper Target Details HTR1D Handhabung Bilder zurück nach oben
Applikationshinweise HTR1D antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-HTR1D Antikörper Target Details HTR1D Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Buffer PBS, 0.02 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung As with all antibodies avoid freeze/thaw cycles.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung HTR1D antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.

Bilder

Produktdetails anti-HTR1D Antikörper Target Details HTR1D Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Serotonin Receptor 1D (HTR1D) (AA 1-18) antibody (ABIN2470118) anti-Serotonin Receptor 1D (HTR1D) (AA 1-18) antibody