Rekombinanter Maus IgG Isotyp-Kontrolle
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- Target Alle IgG Produkte
- IgG
- Antikörpertyp
- Recombinant Antibody
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Wirt
- Maus
- Applikation
- Isotype Control (IsoC), SDS-PAGE (SDS)
- Aufreinigung
- purified by chromatography
- Reinheit
- > 90 % by SDS-PAGE
- Isotyp
- IgG
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Kommentare
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Concentration (detection method): 0.5 mg/mL (determined by Bradford assay)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0)
- Handhabung
- Avoid repeated freezing and thawing cycles.
- Lagerung
- 4 °C
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- Target
- IgG
- Abstract
- IgG Produkte
- Substanzklasse
- Antibody
- Hintergrund
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Immunoglobulin G (IgG) are antibody molecules. Each IgG is composed of four peptide chains (two heavy chains gamma and two light chains). Each IgG has two antigen binding sites. IgG antibodies are involved in predominantly the secondary immune response. The presence of specific IgG, in general, corresponds to maturation of the antibody response. It plays an important role in Antibody-dependent cell-mediated cytotoxicity (ADCC) and Intracellular antibody-mediated proteolysis, in which it binds to TRIM21 (the receptor with greatest affinity to IgG in humans) in order to direct marked virions to the proteasome in the cytosol. Recombinant mouse IgG protein, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography techniques.
Synonyms: Immunoglobulin heavy chain constant region gamma 2a, Immunoglobulin G - Molekulargewicht
- 26.6 kDa (236aa)
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