TGFB1I1 Proteine (TGFB1I1)

Bezeichnung:
Transforming Growth Factor beta 1 Induced Transcript 1 Proteine (TGFB1I1)
Auf www.antikoerper-online.de finden Sie aktuell 11 Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) Proteine von 6 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TGFB1I1 Antikörper (50) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 69 TGFB1I1 Produkte verfügbar.
Synonyme:
ara-55, Ara55, Hic-5, Hic5, TGFB1I1, TSC-5
alle Proteine anzeigen Gen GeneID UniProt
TGFB1I1 7041 O43294
TGFB1I1 21804 Q62219
TGFB1I1 84574 Q99PD6

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Weitere Proteine zu TGFB1I1 Interaktionspartnern

Human Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) Interaktionspartner

  1. Isolated Hic-5(-/-);PyMT CAFs (zeige TBX1 Proteine) were defective in stress fiber organization and exhibited reduced contractility. These cells also failed to efficiently deposit and organize the ECM (zeige MMRN1 Proteine) in two and three dimensions. This, in turn, impacted three-dimensional MDA-MB-231 tumor cell migration behavior

  2. Hic-5 regulates GR binding site selection by a novel mechanism, exploiting gene-specific requirements for chromatin remodeling enzymes to selectively influence DNA occupancy and gene regulation by a transcription factor.

  3. As aging increased, more ARA55 were expressed in PZ stromal cells, leading to more sensitive androgen/androgen receptor (AR (zeige AR Proteine)) signal pathway, then constituting a more feasible environment to cancer cells.

  4. Hic-5 appears to enhance complex formation between MT1-MMP (zeige MMP14 Proteine) and FAK (zeige PTK2 Proteine) in activated endothelial cells, which likely coordinates matrix proteolysis and cell motility.

  5. Hic-5 plays a central role in the positive feedback ROS (zeige ROS1 Proteine)-JNK (zeige MAPK8 Proteine) signaling cascade that regulates hepatocellular carcinoma progression.

  6. Hic-5 influences the genomic occupancy of multiple steroid receptors and thereby blocks some aspects of hormonal regulation.

  7. Endothelial Hic-5 plays an important role in the formation of microvilli-like structures and in the interaction between ECs and monocytes, leading to monocyte recruitment and subsequent development of atherosclerosis.

  8. Studies in vitro and in vivo using TGF-beta1 (zeige TGFB1 Proteine) and TGFB1I1 shRNA demonstrated that TGFB1I1 is required for TGF-beta (zeige TGFB1 Proteine) stimulated EMT (zeige ITK Proteine) that contributes to malignant progression of astrocytomas.

  9. Hic-5 siRNA also suppressed TGF-beta2 (zeige TGFB2 Proteine)-induced fibrogenic activity and dexamethasone-induced myocilin (zeige MYOC Proteine) expression in HTM cells.

  10. Hic5 coordinates AR signaling with adhesion and extracellular matrix contacts to regulate cell behavior in the tumor microenvironment.

Mouse (Murine) Transforming Growth Factor beta 1 Induced Transcript 1 (TGFB1I1) Interaktionspartner

  1. Isolated Hic-5(-/-);PyMT CAFs (zeige TBX1 Proteine) were defective in stress fiber organization and exhibited reduced contractility. These cells also failed to efficiently deposit and organize the ECM (zeige MMRN1 Proteine) in two and three dimensions. This, in turn, impacted three-dimensional MDA-MB-231 tumor cell migration behavior

  2. paxillin (zeige PXN Proteine) and Hic-5 have both redundant and distinctive functions in invadosome formation.

  3. Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis though reducing the TGF-beta (zeige TGFB1 Proteine)/Smad2 (zeige SMAD2 Proteine) signaling by upregulation of Smad7 (zeige SMAD7 Proteine)

  4. Hic-5 regulates mesangial cell proliferation in proliferative glomerulonephritis in mice.

  5. Endothelial Hic-5 plays an important role in the formation of microvilli-like structures and in the interaction between ECs and monocytes, leading to monocyte recruitment and subsequent development of atherosclerosis.

  6. Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor (zeige NR3C1 Proteine) genome occupancy in a gene-selective manner.

  7. Hic-5 is expressed in B16-F1 murine melanoma cells.

  8. identified Hic-5 as a novel and specific regulatory factor for thrombin (zeige F2 Proteine)-induced alphaIIbbeta3 activation and subsequent platelet aggregation in mice.

  9. the HIC-5- and KLF4 (zeige KLF4 Proteine)-dependent mechanism transactivates p21(Cip1 (zeige CDKN1A Proteine)) in response to anchorage loss

  10. These data identify discrete roles for paxillin (zeige PXN Proteine) and Hic-5 in Rac1 and RhoA (zeige RHOA Proteine)-dependent cell adhesion formation and maturation; processes essential for productive cell migration.

TGFB1I1 Protein Überblick

Protein Überblick

This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TGFB1I1

  • transforming growth factor beta 1 induced transcript 1 (TGFB1I1)
  • transforming growth factor beta 1 induced transcript 1 (tgfb1i1)
  • transforming growth factor beta 1 induced transcript 1 (Tgfb1i1)
  • ara-55 Protein
  • Ara55 Protein
  • Hic-5 Protein
  • Hic5 Protein
  • TGFB1I1 Protein
  • TSC-5 Protein

Bezeichner auf Proteinebene für TGFB1I1

transforming growth factor beta 1 induced transcript 1 , androgen receptor coactivator ARA55 , transforming growth factor beta-1-induced transcript 1 protein-like , androgen receptor coactivator 55 kDa protein , androgen receptor-associated protein of 55 kDa , hydrogen peroxide-inducible clone 5 protein , transforming growth factor beta-1-induced transcript 1 protein , TGF beta-stimulated clone 5 , hic-5 , androgen receptor activator of 55 kDa

GENE ID SPEZIES
467962 Pan troglodytes
100038241 Xenopus (Silurana) tropicalis
100391679 Callithrix jacchus
100434548 Pongo abelii
7041 Homo sapiens
21804 Mus musculus
84574 Rattus norvegicus
515834 Bos taurus
779337 Xenopus laevis
489932 Canis lupus familiaris
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