anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Antikörper

Bezeichnung:
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Antikörper (SMARCA4)
Auf www.antikoerper-online.de finden Sie aktuell 100 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Proteine (7) und SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 109 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Produkte verfügbar.
Synonyme:
b2b692Clo, BAF190, BAF190A, brg-1, Brg1, HP1-BP72, hSNF2b, MRD16, RTPS2, SMARCA4, SNF2, SNF2beta, SNF2L4, SNF2LB, SW1/SNF, SWI2
Alle Antikörper anzeigen Gen GeneID UniProt
SMARCA4 6597 P51532
SMARCA4 171379  
SMARCA4 20586 Q3TKT4

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Weitere Synonyme anzeigen

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Am meisten referenzierte anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Antikörper

  1. Human Monoclonal SMARCA4 Primary Antibody für IHC (p), WB - ABIN614772 : Ooi, Belyaev, Miyake, Wood, Buckley: BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression. in The Journal of biological chemistry 2006 (PubMed)
    Zeige alle 4 Referenzen für 614772

  2. Human Polyclonal SMARCA4 Primary Antibody für ChIP, ICC - ABIN4285245 : Miyamoto, Pasque, Jullien, Gurdon: Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes. in Genes & development 2011 (PubMed)
    Zeige alle 4 Referenzen für 4285245

  3. Human Monoclonal SMARCA4 Primary Antibody für WB - ABIN343708 : Griffin, Brennan, Magnuson: The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development. in Development (Cambridge, England) 2008 (PubMed)
    Zeige alle 4 Referenzen für 343708

  4. Human Polyclonal SMARCA4 Primary Antibody für WB - ABIN871762 : Park, Venteicher, Hong, Choi, Jun, Shkreli, Chang, Meng, Cheung, Ji, McLaughlin, Veenstra, Nusse, McCrea, Artandi: Telomerase modulates Wnt signalling by association with target gene chromatin. in Nature 2009 (PubMed)
    Zeige alle 3 Referenzen für 871762

  5. Human Polyclonal SMARCA4 Primary Antibody für WB - ABIN686122 : Chen, Han, Wei, Zhang, Shi, Duan, Li, Zhou, Pu, Zhang, Kang: SNORD76, a box C/D snoRNA, acts as a tumor suppressor in glioblastoma. in Scientific reports 2015 (PubMed)

  6. Human Monoclonal SMARCA4 Primary Antibody für ICC, IF - ABIN2668499 : Ohkawa, Harada, Nakamura, Yoshimura, Tachibana: Production of a rat monoclonal antibody against Brg1. in Hybridoma (2005) 2009 (PubMed)

  7. Human Monoclonal SMARCA4 Primary Antibody für ICC, IF - ABIN2668498 : de la Serna, Ohkawa, Higashi, Dutta, Osias, Kommajosyula, Tachibana, Imbalzano: The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes. in The Journal of biological chemistry 2006 (PubMed)

Weitere Antikörper gegen SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Interaktionspartner

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Interaktionspartner

  1. BRG1 was significantly increased in hepatocellular carcinoma. Overexpression of BRG1 increases cell growth and invasiveness in HCC (zeige FAM126A Antikörper).

  2. Case Report: SMARCA4 nonsense/frameshift mutations responsible for concomitant Coffin-Siris syndrome, microphthalmia and small-cell carcinoma of the ovary hypercalcaemic type.

  3. i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene

  4. Brg1 coordinates a genetic and epigenetic network that regulates the transcriptional program underlying the Shh (zeige SHH Antikörper)-type medulloblastoma development.

  5. whole-genome transcriptome analysis revealed that BRG1 controls the expression of key elements of oncogenic pathways such as PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) and BCL2 (zeige BCL2 Antikörper), which offers a promising new combination therapy for high-risk Neuroblastoma (zeige ARHGEF16 Antikörper) (NB).

  6. A breakdown in a BRCA/FANCD2 (zeige FANCD2 Antikörper)/BRG1/SNF (zeige SNRPA Antikörper)-DeltaNP63-mediated DNA repair and differentiation maintenance process in mammary epithelial cells may contribute to sporadic breast cancer development.

  7. both ABCB1 (zeige ABCB1 Antikörper) upregulation and doxorubicin resistance caused by SMARCB1 (zeige SMARCB1 Antikörper) loss were dependent on the function of SMARCA4, a catalytic subunit of the SWI (zeige SMARCA1 Antikörper)/SNF (zeige SNRPA Antikörper) complex.

  8. BRG1 participates in gene repression by interacting with H1.2 (zeige HIST1H1C Antikörper), facilitating its deposition and stabilizing nucleosome positioning around the transcription start site.

  9. Cdx (zeige CDX1 Antikörper) members interact with the SWI (zeige SMARCA1 Antikörper)-SNF (zeige SNRPA Antikörper) complex and make direct contact with Brg1, a catalytic member of SWI (zeige SMARCA1 Antikörper)-SNF (zeige SNRPA Antikörper). Both Cdx2 (zeige CDX2 Antikörper) and Brg1 co-occupy a number of Cdx (zeige CDX1 Antikörper) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 (zeige CDX2 Antikörper) and Brg1 occupancy occurs coincident with chromatin remodeling at some of these loci.

  10. BRG1/BRM (zeige SMARCA2 Antikörper) and c-MYC (zeige MYC Antikörper) have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (zeige RAB1A Antikörper) in cancer.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Interaktionspartner

  1. Data demonstrate that Brg1 plays an essential role in development and homeostasis, including morphogenesis, stem cell differentiation and cell survival in the duodenum.

  2. Point mutations in SMARCA4 (also known as BRG1) mapping to the ATPase (zeige DNAH8 Antikörper) domain cause loss of direct binding between BAF (zeige BANF1 Antikörper) and PRC1 (zeige PRC1 Antikörper).

  3. BRG1 promotes transcription of endothelial Mrtfa and Mrtfb, which elevates expression of SRF and SRF target genes that establish embryonic capillary integrity.

  4. RB is necessary for the recruitment of the BRG1 ATPase (zeige DNAH8 Antikörper) to DNA double-strand breaks, which stimulates DNA end resection and homologous recombination

  5. Cdx (zeige CDX1 Antikörper) members interact with the SWI (zeige SMARCA1 Antikörper)-SNF (zeige SNRPA Antikörper) complex and make direct contact with Brg1, a catalytic member of SWI (zeige SMARCA1 Antikörper)-SNF (zeige SNRPA Antikörper). Both Cdx2 (zeige CDX2 Antikörper) and Brg1 co-occupy a number of Cdx (zeige CDX1 Antikörper) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 (zeige CDX2 Antikörper) and Brg1 occupancy occurs coincident with chromatin remodeling at some of these loci.

  6. BRG1/BRM (zeige SMARCA2 Antikörper) and c-MYC (zeige MYC Antikörper) have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (zeige RAB1A Antikörper) in cancer.

  7. Results provide insights into the mechanisms by which Brg1 functions, which is in part via the p53 (zeige TP53 Antikörper) program, to constrain gene expression and facilitate rapid embryonic growth.

  8. Brg1 promotes neurogenic radial glial progenitor cell specification but is dispensable for neuronal differentiation

  9. SWI (zeige SMARCA1 Antikörper)/SNF (zeige SNRPA Antikörper) chromatin remodeler subunits Brg1 and Brm (zeige SMARCA2 Antikörper) are expressed differentially during drug-induced liver injury and regeneration in a mouse model.

  10. these findings described a role for BRG1 and BRM (zeige SMARCA2 Antikörper) in mitochondrial quality control, by regulating mitochondrial number, mitophagy, and mitochondrial dynamics not previously recognized in the adult cardiomyocyte

SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4)

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4) Antikörper
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (Smarca4) Antikörper
  • b2b692Clo Antikörper
  • BAF190 Antikörper
  • BAF190A Antikörper
  • brg-1 Antikörper
  • Brg1 Antikörper
  • HP1-BP72 Antikörper
  • hSNF2b Antikörper
  • MRD16 Antikörper
  • RTPS2 Antikörper
  • SMARCA4 Antikörper
  • SNF2 Antikörper
  • SNF2beta Antikörper
  • SNF2L4 Antikörper
  • SNF2LB Antikörper
  • SW1/SNF Antikörper
  • SWI2 Antikörper

Bezeichner auf Proteinebene für SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 , transcription activator BRG1-like , ATP-dependent helicase SMARCA4 , BRG1-associated factor 190A , BRM/SWI2-related gene 1 , SNF2-beta , SNF2-like 4 , brahma protein-like 1 , global transcription activator homologous sequence , homeotic gene regulator , mitotic growth and transcription activator , nuclear protein GRB1 , protein BRG-1 , protein brahma homolog 1 , sucrose nonfermenting-like 4 , transcription activator BRG1 , BAF190A , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 , SWI/SNF related transcriptional activator , WI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

GENE ID SPEZIES
455720 Pan troglodytes
476710 Canis lupus familiaris
100415454 Callithrix jacchus
100446301 Pongo abelii
100464834 Ailuropoda melanoleuca
6597 Homo sapiens
171379 Rattus norvegicus
20586 Mus musculus
414274 Bos taurus
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