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Prohibitin 2 Proteine (PHB2)

Bezeichnung:
Prohibitin 2 Proteine (PHB2)
Auf www.antikoerper-online.de finden Sie aktuell 8 Prohibitin 2 (PHB2) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Prohibitin 2 Antikörper (127) und Prohibitin 2 Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 149 Prohibitin 2 Produkte verfügbar.
Synonyme:
ATPHB2, AU044498, Bap, Bap-37, bap37, Bcap27, Bcap37, DKFZp469N1310, F21M11.21, F21M11_21, p22, phb2, PNAS-141, prohibitin 2, prohibitin2, REA, wu:fc28c08, xphb2, zgc:73150
alle Proteine anzeigen Gen GeneID UniProt
PHB2 11331 Q99623
PHB2 12034 O35129
Ratte PHB2 PHB2 114766 Q5XIH7

Weitere Synonyme anzeigen

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Am meisten referenzierte Prohibitin 2 Proteine

  1. Human Prohibitin 2 Protein expressed in Wheat germ - ABIN1314865 : Mishra, Moulik, Murphy: Prohibitin binds to C3 and enhances complement activation. in Molecular immunology 2006 (PubMed)

Weitere Proteine zu Prohibitin 2 Interaktionspartnern

Human Prohibitin 2 (PHB2) Interaktionspartner

  1. analysis of LGALS3, PHB2, MUC1, and GK2 expression with CA15-3 in early-stage breast cancer

  2. Fluorizoline bind to prohibitin (zeige PHB Proteine), inducing mitochondrial apoptotic pathway through NOXA (zeige PMAIP1 Proteine) and BIM (zeige BCL2L11 Proteine) upregulation.

  3. REA modulates cross talk among multiple cell types in the uterine tissue and host background, serving as a brake on the estradiol-ER axis and restraining multiple aspects that contribute to the pathologic progression of endometriosis.

  4. BIG3 (zeige WDR5 Proteine) may block the KPNAs (KPNA1 (zeige KPNA1 Proteine), KPNA5 (zeige KPNA5 Proteine), and KPNA6 (zeige KPNA6 Proteine)) binding region(s) of PHB2.

  5. results show that PHB2 binds to the ligand binding domain of ERalpha (zeige ESR1 Proteine) with a conformational change in the helix 12 of ERalpha (zeige ESR1 Proteine)

  6. Functional analysis of selected regulated proteins revealed that knockdown of HNRPD (zeige HNRNPD Proteine), PHB2 and UB2V2 (zeige UBE2V2 Proteine) can increase HCMV replication, while knockdown of A4 and KSRP (zeige KHSRP Proteine) resulted in decreased HCMV replication.

  7. These results demonstrate that estradiol upregulates REA expression and recruits REA via ERalpha (zeige ESR1 Proteine) to the EREs on the RORgammaT promoter region, thus inhibiting RORgammaT expression and Th17 differentiation.

  8. BIG3 (ARFGEF3) is predicted to interact with its partner PHB2 through an ARM-type alpha-helical structure.

  9. Data indicate that the up-regulated expression of prohibitin (zeige PHB Proteine) promoted acute promyelocytic leukemia (zeige PML Proteine) cell line NB4-R1 cell apoptosis.

  10. PHB2 in hepatocellular carcinoma supports the development and progression of hepatocellular malignancy.

Mouse (Murine) Prohibitin 2 (PHB2) Interaktionspartner

  1. Fluorizoline bind to prohibitin (zeige PHB Proteine), inducing mitochondrial apoptotic pathway through NOXA (zeige PMAIP1 Proteine) and BIM (zeige BCL2L11 Proteine) upregulation.

  2. REA modulates cross talk among multiple cell types in the uterine tissue and host background, serving as a brake on the estradiol-ER axis and restraining multiple aspects that contribute to the pathologic progression of endometriosis.

  3. CARL can suppress mitochondrial fission and apoptosis by targeting miR (zeige MLXIP Proteine)-539 and PHB2.

  4. These results demonstrate that estradiol upregulates REA expression and recruits REA via ERalpha (zeige ESR1 Proteine) to the EREs on the RORgammaT promoter region, thus inhibiting RORgammaT expression and Th17 differentiation.

  5. results suggest that PHB2 is a crucial mitochondrial regulator for homeostasis and lineage-specific differentiation of ES cells.

  6. Loss of PHB2 impairs the stability of OPA1, affects mitochondrial ultrastructure, and induces the perinuclear clustering of mitochondria in hippocampal neurons

  7. REA physiologically restrains endometrial stromal cell decidualization, controlling the timing and magnitude of decidualization to coordinate uterine differentiation with concurrent embryo development that is essential for implantation and fertility.

  8. PHB1 (zeige PHB Proteine) and PHB2 are critical mediators in promoting 3T3-L1 adipocyte differentiation and may be the potential targets for obesity therapies

  9. Optimal uterine development and functional activities require the normal gene dosage of REA, with partial or complete deletion resulting in hyperresponsiveness or underresponsiveness to hormone and subfertility or infertility, respectively.

  10. Serine phosphorylation of PHB2 by CaMK IV (zeige CAMK4 Proteine) relieves its inhibition on MEF2 (zeige MEF2C Proteine).

Prohibitin 2 (PHB2) Protein Überblick

Protein Überblick

Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging (By similarity).

Alternative names and synonyms associated with Prohibitin 2 (PHB2)

  • prohibitin 2 (phb2)
  • prohibitin 2 (PHB2)
  • prohibitin 2 (TGas064h09.1)
  • prohibitin 2 (Phb2)
  • ATPHB2 Protein
  • AU044498 Protein
  • Bap Protein
  • Bap-37 Protein
  • bap37 Protein
  • Bcap27 Protein
  • Bcap37 Protein
  • DKFZp469N1310 Protein
  • F21M11.21 Protein
  • F21M11_21 Protein
  • p22 Protein
  • phb2 Protein
  • PNAS-141 Protein
  • prohibitin 2 Protein
  • prohibitin2 Protein
  • REA Protein
  • wu:fc28c08 Protein
  • xphb2 Protein
  • zgc:73150 Protein

Bezeichner auf Proteinebene für Prohibitin 2 Proteine (PHB2)

B-cell receptor-associated protein 37 , prohibitin 2 , Prohibitin-2 , B-cell associated protein , B-cell receptor-associated protein BAP37 , D-prohibitin , prohibitin-2 , repressor of estrogen receptor activity , B-cell receptor associated protein 37

GENE ID SPEZIES
324421 Danio rerio
451805 Pan troglodytes
549305 Xenopus (Silurana) tropicalis
839228 Arabidopsis thaliana
100172520 Pongo abelii
11331 Homo sapiens
446470 Xenopus laevis
771124 Gallus gallus
486716 Canis lupus familiaris
515363 Bos taurus
12034 Mus musculus
114766 Rattus norvegicus
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