PPARGC1A (PPARGC1A) ELISA Kits

Bezeichnung:
Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha ELISA Kits (PPARGC1A)
Auf www.antikoerper-online.de finden Sie aktuell 2 Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) ELISA Kits von 2 unterschiedlichen Herstellern. Insgesamt sind aktuell 2 PPARGC1A Produkte verfügbar.
Synonyme:
A830037N07Rik, AVPGC-1ALPHA, ENSMUSG00000079510, Gm11133, LEM6, PGC-1, PGC-1(alpha), Pgc-1alpha, PGC-1v, PGC1, PGC1A, Pgco1, Ppargc1, PPARGC1A
list all ELISA KIts Gen GeneID UniProt
PPARGC1A 19017 O70343
PPARGC1A 10891 Q9UBK2
Ratte PPARGC1A PPARGC1A 83516 Q9QYK2

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PPARGC1A (PPARGC1A) ELISA Kits nach Reaktivitäten

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Weitere ELISA Kits für PPARGC1A Interaktionspartner

Mouse (Murine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) Interaktionspartner

  1. Destabilization of PGC1a is attributable to decreased p38 MAPK (zeige MAPK14 ELISA Kits) activation via diminished CaMKII (zeige CAMK2G ELISA Kits) signaling. Thus, we elucidate a pathway downstream of Ca(2 (zeige CA2 ELISA Kits)+)-mediated CaMKII (zeige CAMK2G ELISA Kits) activation that is dysfunctional in C3KO(Capn3 (zeige CAPN3 ELISA Kits) knock-out mice ) mice, leading to reduced transcription of genes involved in muscle adaptation

  2. lncBATE10 can decoy Celf1 (zeige CELF1 ELISA Kits) from Pgc1alpha, thereby protecting Pgc1alpha mRNA from repression by Celf1 (zeige CELF1 ELISA Kits)

  3. Since the R6/2 mice represent a 'truncated' huntingtin (Htt (zeige HTT ELISA Kits)) mouse model of Huntington's disease (HD), we tested the efficacy of bezafibrate in a 'full-length' Htt (zeige HTT ELISA Kits) mouse model, the BACHD mice. Bezafibrate treatment restored the impaired PPARg (zeige PPARG ELISA Kits), PPARd (zeige PPARD ELISA Kits), PGC (zeige PGC ELISA Kits)-1a signaling pathway, enhanced mitochondrial biogenesis and improved antioxidant defense in the striatum of BACHD mice

  4. this study shows that PGC-1alpha overexpression improves metabolism in virus-specific CD8 (zeige CD8A ELISA Kits)+ T cells generated during acute infection

  5. This is the first study to dissect the mechanism by which the antiadipogenic and anti-inflammatory lipid, Epoxyeicosatrienoic acid, induces the PGC-1alpha signaling cascade and reprograms the adipocyte phenotype by regulating mitochondrial function and HO-1 (zeige HMOX1 ELISA Kits) expression.

  6. The accelerated conversion of T4 to T3 within myocytes mediates part of the PGC (zeige PGC ELISA Kits)-1a induction by treadmill exercise and its downstream effects on mitochondrial function

  7. Study demonstrates a novel role for peroxisome proliferator-activated receptor gamma (zeige PPARG ELISA Kits) coactivator-1alpha (PGC-1alpha) in nucleus accumbens (NAc (zeige NLRP1 ELISA Kits)) in cocaine action. PGC-1alpha is enhanced in NAc (zeige NLRP1 ELISA Kits) dopamine D1-medium spiny neurons, specifically after cocaine exposure. These data are consistent with increased active methylation and early growth response 3 (zeige EGR3 ELISA Kits) binding at the PGC-1alpha promoter.

  8. These data reveal a new role for muscle PGC-1alpha in regulating the physiological adaptation to long-term LCHF diet administration.

  9. These results demonstrate a central role of skeletal muscle PGC-1alpha in the transcriptional regulation of systemic ketolytic capacity.

  10. Our results indicate that prolonged Htr2b (zeige HTR2B ELISA Kits) activation in murine beta-cells decreases glucose-stimulated insulin (zeige INS ELISA Kits) secretion and mitochondrial activity by mechanisms likely dependent on enhanced PGC1a/PPARygexpression.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) Interaktionspartner

  1. Study investigated the molecular basis of such effects focusing on a commonly studied polymorphism in pig Pgc1alpha, which changes a cysteine at position 430 (WT) of the protein to a serine (C430S); found that differential O-GlcNAcylation of Pgc1alpha regulates PCK1 (zeige PCK1 ELISA Kits) activity and this molecular mechanism could explain at least in part the epistatic interaction between both genes.

  2. Transcription of the gene was detected in adipose, muscle, kidney, liver, brain, heart and adrenal gland tissues, which is in agreement with the function of PPARGC1A in adaptive thermogenesis.

  3. The purpose of this study was to screen for new single nucleotide polymorphisms in exon 8 of the porcine PPARGC1A gene and to test their possible association with production traits.

  4. impact of PPARGC1A on energy and lipid metabolism in vivo, through several downstream target genes

  5. The *2690T>C and *2864T>C polymorphisms in PPARGC1A can be used as genetic markers for selection toward improved meat quality.

  6. The c.-2894G>A polymorphism in the 5' upstream region of the porcine PPARGC1A gene can be used as a meaningful molecular marker for simultaneous improvement of lean meat production and quality traits.

  7. PPARGC1A may play a key role in down-regulating lipid deposition, and the SNPs with differential genotype distribution among three breeds may be related to gene expression and fat deposition.

  8. Polymorphisms in PPARGC1A and CAPNS1 (zeige CAPNS1 ELISA Kits) genes may affect meat quality traits.

Human Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) Interaktionspartner

  1. Low-intensity endurance cycling exercise performed with blood flow restriction failed to increase PGC-1alpha expression to that commonly observed with endurance exercise. Isoform-specific postexercise increases in the alpha4 isoform along with Hif-1alpha and VEGF mRNA expression following higher intensity endurance exercise without blood flow restriction.

  2. These results highlight the combined effects of Parkin (zeige PARK2 ELISA Kits) and PGC-1alpha in the maintenance of mitochondrial homeostasis in dopaminergic neurons. These two factors synergistically control the quality and function of mitochondria, which is important for the survival of neurons in Parkinson's disease.

  3. PPARGC1A rs4235308 has no significant association with ALS.

  4. Supplementation of omega-3 fatty acids in combination with vitamin E may have beneficial effects on coronary artery disease patients by increasing gene expression of SIRT1 (zeige SIRT1 ELISA Kits) and PGC1alpha and improving oxidative stress and inflammation in these patients.

  5. Results delineate a cross talk between a central pathway controlling metabolic regulation and cell adhesion, and identify PGC-1alpha as a molecular link between these two major cellular networks.

  6. Haplotype-based interaction between the PPARGC1A and UCP1 (zeige UCP1 ELISA Kits) genes is associated with impaired fasting glucose (IFG (zeige IFNG ELISA Kits)) or type 2 diabetes mellitus (T2DM) among the residents of Henan province, China. Individuals with the haplotype AAG (zeige MPG ELISA Kits) (PPARGC1A gene) and CTCG (UCP1 (zeige UCP1 ELISA Kits) gene) have increased susceptibility to IFG (zeige IFNG ELISA Kits) or T2DM, while those with haplotype AAG (zeige MPG ELISA Kits) (PPARGC1A gene) and CTCA (UCP1 (zeige UCP1 ELISA Kits) gene) have a lower risk of IFG (zeige IFNG ELISA Kits) or T2DM.

  7. The miR (zeige MLXIP ELISA Kits)-130b-3p down-regulates PGC-1alpha expression in placental trophoblasts, and inhibition of miR (zeige MLXIP ELISA Kits)-130b-3p appears to improve mitochondrial biogenesis signaling and protect placental trophoblast cells from oxidative stress.

  8. the RAR-related orphan receptor-a (zeige RORA ELISA Kits) gene (RORA (zeige RORA ELISA Kits)) and the Peroxisome Proliferator-Activated Receptor Gamma (zeige PPARG ELISA Kits), Coactivator 1 Alpha gene (PPARGC1A or PGC-1alpha) were significantly associated with the Li response. Our results suggest genetic associations between Li response and these two close biological partners: PPARGC1A and RORA (zeige RORA ELISA Kits) involved in circadian rhythms and bioenergetics processes in Li response

  9. Schizophrenia involves a disruption in PGC-1alpha and/or NRF-1 (zeige NFE2L1 ELISA Kits)-associated transcriptional programs in the cortex.

  10. In molecular dynamics simulations, PGC1alpha induced correlated atomic motion throughout the entire LRH-1 (zeige NR5A2 ELISA Kits) activation function surface.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) Interaktionspartner

  1. PPARGC1A single nucleotide polymorphisms associated with milk fatty acids in a Chinese Holstein cattle.

  2. The PPARGC1A synonymous mutation c.396G>A significantly associated with body weight and average daily gain in Nanyang cattle at the adult age.

  3. PPARGC1A genotypes had a significant effect on lengths of calving interval and calving to conception interval, and the T allele was demonstrated to have an unfavourable effect on these traits.

  4. NO/protein kinase (zeige CDK7 ELISA Kits) G (PKG (zeige PRKG1 ELISA Kits))-dependent downregulation of PGC-1 alpha and the ROS (zeige ROS1 ELISA Kits) detoxification system in endothelial cells are mediated by the PI3K/Akt (zeige AKT1 ELISA Kits) signaling

  5. The effects of dietary fat components on the expression of PPAR-gamma (zeige PPARG ELISA Kits) AND PPAR-gamma coactivator 1 in cultured bovine preadipocytes are reported.

  6. genetic analysis of bovine PPARGC1A

  7. PPARGC1A was associated with a significant increase in milk protein (zeige CSN2 ELISA Kits) percentage in contrast to association results previously reported for the German Holstein population

PPARGC1A Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Alternative names and synonyms associated with PPARGC1A

  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PPARGC1A) Elisa Kit
  • peroxisome proliferative activated receptor, gamma, coactivator 1 alpha (Ppargc1a) Elisa Kit
  • peroxisome proliferator activated receptor gamma, coactivator 1 alpha (PPARGC-1) Elisa Kit
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (Ppargc1a) Elisa Kit
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (ppargc1a) Elisa Kit
  • A830037N07Rik Elisa Kit
  • AVPGC-1ALPHA Elisa Kit
  • ENSMUSG00000079510 Elisa Kit
  • Gm11133 Elisa Kit
  • LEM6 Elisa Kit
  • PGC-1 Elisa Kit
  • PGC-1(alpha) Elisa Kit
  • Pgc-1alpha Elisa Kit
  • PGC-1v Elisa Kit
  • PGC1 Elisa Kit
  • PGC1A Elisa Kit
  • Pgco1 Elisa Kit
  • Ppargc1 Elisa Kit
  • PPARGC1A Elisa Kit

Bezeichner auf Proteinebene für PPARGC1A

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha , PPAR-gamma coactivator , peroxisome proliferator activated receptor gamma coactivator-1 , PGC-1-alpha , PPAR Gamma Coactivator-1 , PPAR gamma coactivator variant form , PPAR-gamma coactivator 1-alpha , PPARGC-1-alpha , Pgc-1alphaa , peroxisome proliferator-activated receptor gamma coactivator 1-alpha , L-PGC-1alpha , ligand effect modulator-6 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT , peroxisome proliferative activated receptor, gamma, coactivator 1 , peroxisome proliferator activated receptor gamma coactivator 1 alpha , PGC-1alpha , peroxisome proliferative activated receptor gamma coactivator 1 , peroxisome proliferative activated receptor, gamma, coactivator 1 alpha , proliferator-activated receptor gamma coactivator 1 alpha , peroxisome proliferative activated receptor, gamma, coactivator 1, alpha , peroxisome-proliferator-activated receptor-gamma co-activator-1

GENE ID SPEZIES
443270 Ovis aries
19017 Mus musculus
397013 Sus scrofa
10891 Homo sapiens
479127 Canis lupus familiaris
338446 Bos taurus
83516 Rattus norvegicus
100462892 Xenopus laevis
422815 Gallus gallus
100349219 Oryctolagus cuniculus
100721512 Cavia porcellus
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