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NCOA4 Proteine (NCOA4)

Bezeichnung:
Nuclear Receptor Coactivator 4 Proteine (NCOA4)
Auf www.antikoerper-online.de finden Sie aktuell 6 Nuclear Receptor Coactivator 4 (NCOA4) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NCOA4 Antikörper (83) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 96 NCOA4 Produkte verfügbar.
Synonyme:
1110034E15Rik, 4432406M01Rik, AI227008, ARA70, DKFZp459B2429, DKFZp469A035, DKFZp469A1925, ELE1, MGC84996, MGC138109, ncoa4, PTC3, Rfg, zgc:55307, zgc:77270
alle Proteine anzeigen Gen GeneID UniProt
Ratte NCOA4 NCOA4 619385  
NCOA4 8031 Q13772
Maus NCOA4 NCOA4 27057  

Weitere Synonyme anzeigen

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Weitere Proteine zu NCOA4 Interaktionspartnern

Xenopus laevis Nuclear Receptor Coactivator 4 (NCOA4) Interaktionspartner

  1. NCOA4 acts as a regulator of DNA replication origins that helps prevent inappropriate DNA synthesis and replication stress.

Human Nuclear Receptor Coactivator 4 (NCOA4) Interaktionspartner

  1. Ubiquitin-dependent NCOA4 turnover is promoted by excess iron and involves an iron-dependent interaction between NCOA4 and the HERC2 ubiquitin ligase.

  2. Studies indicate nuclear receptor coactivator 4 (NcoA4) as a coactivator for a variety of nuclear receptors.

  3. provide a new mechanism for selective autophagy of ferritin (zeige FTL Proteine) and reveal a previously unappreciated role for autophagy and NCOA4 in the control of iron homeostasis in vivo

  4. RET (zeige RET Proteine)/PTC3 gene rearrangements are the most prevalent form of rearrangements in papillary thyroid carcinomas of Chennai population.

  5. NCOA4 acts as a regulator of DNA replication origins that helps prevent inappropriate DNA synthesis and replication stress.

  6. identification of NCOA4 as a selective cargo receptor for autophagic turnover of ferritin (zeige FTL Proteine) (ferritinophagy), which is critical for iron homeostasis, and provides a resource for further dissection of autophagosomal cargo-receptor connectivity

  7. mechanism dissection shows that KLK2 (zeige KLK2 Proteine) may cooperate with the AR coregulator, ARA70, to enhance AR transactivation that may result in alteration of prostate cancer formation

  8. Data indicate that the increase in prostate cancer (PC) risk associated with rs10993994:C>T is likely mediated by the variant's effect of MSMB (zeige MSMB Proteine)-encoded protein PSP94 (zeige MSMB Proteine) expression; however, this effect does not extend to NCOA4 in the data.

  9. Computational network analysis reveals that the MSMB (zeige MSMB Proteine) gene is functionally connected to NCOA4 and the androgen receptor (zeige AR Proteine) signaling pathway. The data provide an example of how GWAS-associated variants may have multiple genetic and epigenetic effects

  10. Suppression of MSMB (zeige MSMB Proteine) expression or NCOA4 overexpression promotes anchorage-independent growth of prostate epithelial cells.

Mouse (Murine) Nuclear Receptor Coactivator 4 (NCOA4) Interaktionspartner

  1. NCOA4 prevents iron accumulation and ensures efficient erythropoiesis, playing a central role in balancing iron levels in vivo.

  2. provide a new mechanism for selective autophagy of ferritin (zeige FTL Proteine) and reveal a previously unappreciated role for autophagy and NCOA4 in the control of iron homeostasis in vivo

  3. NCOA4 acts as a regulator of DNA replication origins that helps prevent inappropriate DNA synthesis and replication stress.

  4. Results demonstrate ubiquitous NcoA4 expression throughout development and suggest that this coactivator may play a role in modulating nuclear receptor activity, particularly that of the aryl hydrocarbon receptor (zeige AHR Proteine), during development.

  5. Data suggest that myostatin (zeige MSTN Proteine) decreases the activity of androgen receptors (AR) by down-regulating the expression of ARA70, a known stimulating co-factor of AR

NCOA4 Protein Überblick

Protein Überblick

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

Alternative names and synonyms associated with NCOA4

  • nuclear receptor coactivator 4 (Ncoa4)
  • nuclear receptor coactivator 4 (ncoa4)
  • nuclear receptor coactivator 4 (NCOA4)
  • Nuclear receptor coactivator 4 (ncoa4)
  • 1110034E15Rik Protein
  • 4432406M01Rik Protein
  • AI227008 Protein
  • ARA70 Protein
  • DKFZp459B2429 Protein
  • DKFZp469A035 Protein
  • DKFZp469A1925 Protein
  • ELE1 Protein
  • MGC84996 Protein
  • MGC138109 Protein
  • ncoa4 Protein
  • PTC3 Protein
  • Rfg Protein
  • zgc:55307 Protein
  • zgc:77270 Protein

Bezeichner auf Proteinebene für NCOA4

nuclear receptor coactivator 4 , Nuclear receptor coactivator 4 , 70 kDa AR-activator , 70 kDa androgen receptor coactivator , NCoA-4 , RET-activating gene ELE1 , androgen receptor-associated protein of 70 kDa , ret fused

GENE ID SPEZIES
619385 Rattus norvegicus
394104 Danio rerio
423615 Gallus gallus
450455 Pan troglodytes
525329 Bos taurus
734285 Xenopus laevis
100156184 Sus scrofa
100172727 Pongo abelii
100306816 Salmo salar
8031 Homo sapiens
27057 Mus musculus
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