Solute Carrier Family 5 Member 3 Proteine (SLC5A3)

Bezeichnung:
Solute Carrier Family 5 Member 3 Proteine (SLC5A3)
Auf www.antikoerper-online.de finden Sie aktuell 6 Solute Carrier Family 5 Member 3 (SLC5A3) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Solute Carrier Family 5 Member 3 Antikörper (68) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 77 Solute Carrier Family 5 Member 3 Produkte verfügbar.
Synonyme:
AA623876, BF642829, Smit, SMIT1, SMIT2
alle Proteine anzeigen Gen GeneID UniProt
SLC5A3 53881 Q9JKZ2
SLC5A3 6526 P53794
Ratte SLC5A3 SLC5A3 114507  

Weitere Synonyme anzeigen

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Weitere Proteine zu Solute Carrier Family 5 Member 3 Interaktionspartnern

Mouse (Murine) Solute Carrier Family 5 Member 3 (SLC5A3) Interaktionspartner

  1. KCNQ1 (zeige KCNQ1 Proteine), KCNE2 (zeige KCNE2 Proteine), and SMIT1 form reciprocally regulating complexes that affect neuronal excitability.

  2. activation of NFAT5 (zeige NFAT5 Proteine) and its downstream SMIT induction is important in protecting neurons from ischemia-induced oxidative stress

  3. At low concentration, where SMIT1/2 activity gains importance, myo-inositol uptake is reduced by ammonia-induced intracellular acidification

  4. These findings add Mus (zeige TRPV6 Proteine) spicilegus endogenous retrovirus HEMV as a second member to the murine leukemia virus subgroup that uses mSMIT1 to gain entry into cells.

  5. brain SMIT1 levels were higher than SMIT2, however, regional differences were observed

  6. Sodium/MI cotransporter 1 (SMIT1, the major cotransporter of MI) knockout (SMIT1(-/-)) mice with markedly reduced tissue myoinositol (MI) levels were used to characterize the essential roles of MI and SMIT1 in osteogenesis.

  7. SLC5a3 is responsible for the Ins (zeige INS Proteine) concentration gradient in the murine fetal-placental unit

  8. used by Mus (zeige TRPV6 Proteine) cervicolor Murine Leukemia Virus for cell entry

  9. When Sertoli cells were cultured in a hypertonic medium, there was an increase in the expression of Isyna1 (zeige ISYNA1 Proteine) and Slc5a3

  10. SMIT-1 has a role in the development and function of the peripheral nerves

Human Solute Carrier Family 5 Member 3 (SLC5A3) Interaktionspartner

  1. SMIT1 Modifies KCNQ (zeige KCNQ1 Proteine) Channel Function and Pharmacology by Physical Interaction with the Pore

  2. overexpression of the Na(+)/myo-inositol cotransporter (SMIT1) and myo-inositol supplementation enlarged intracellular PI(4,5)P2 pools, modulated several PI(4,5)P2-dependent ion channels including KCNQ2 (zeige KCNQ2 Proteine)/3 channels, and attenuated the action potential firing of superior cervical ganglion neurons

  3. Hypotonic stress causes a significant upregulation of SLC5A3 gene expression as detected by semiquantitative RT-PCR and Western blot analysis.

  4. A kinetic model has been generated for the transport mechanism of SMIT2 allowing insight into the transport of members of the LeuT structural family at the millisecond timescale.

  5. JAK2 (zeige JAK2 Proteine) contributes to the regulation of the myoinositol transporter SMIT.

  6. Tumor cells silence SLC5A8 and convert pyruvate into lactate as complementary mechanisms to avoid pyruvate-induced cell death.

  7. Expression and/or function of SMIT2 may be reduced in diabetes mellitus, insulin (zeige INS Proteine) resistance and polycystic ovary syndrome causing abnormal inositol meteabolism

Solute Carrier Family 5 Member 3 (SLC5A3) Protein Überblick

Protein Überblick

Functions as a retroviral receptor for M813 murine leukemia virus (MuLV) entry. Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.

Alternative names and synonyms associated with Solute Carrier Family 5 Member 3 (SLC5A3)

  • solute carrier family 5 (inositol transporters), member 3 (Slc5a3)
  • solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 (SLC5A3)
  • solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 (Slc5a3)
  • AA623876 Protein
  • BF642829 Protein
  • Smit Protein
  • SMIT1 Protein
  • SMIT2 Protein

Bezeichner auf Proteinebene für SLC5A3

Na(+)/myo-inositol cotransporter , sodium myo-inositol transporter 1 , sodium/myo-inositol cotransporter , sodium/myo-inositol transporter 1 , solute carrier family 5 member 3 , solute carrier family 5, member 3 , solute carrier family 5, member alpha 3 , BCW2 protein , human solute carrier family 5, member 3, Sodium/myo-inositol cotransporter , sodium/myo-inositol cotransporter 1 , solute carrier family 5 (inositol transporter), member 3 , solute carrier family 5 (inositol transporters), member 3 , osmoregulatory Na+/myo-inositol cotransporter

GENE ID SPEZIES
53881 Mus musculus
6526 Homo sapiens
114507 Rattus norvegicus
282362 Bos taurus
445542 Canis lupus familiaris
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