anti-TRPV4 (TRPV4) Antikörper

Bezeichnung:
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 Antikörper (TRPV4)
Auf www.antikoerper-online.de finden Sie aktuell 101 Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TRPV4 Proteine (6) und TRPV4 Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 123 TRPV4 Produkte verfügbar.
Synonyme:
0610033B08Rik, CMT2C, HMSN2C, Otrpc4, SMAL, SPSMA, SSQTL1, Trp12, VR-OAC, VRL-2, VRL2, Vroac, wu:fp52e02

Meistgesuchte Reaktivitäten zu anti-TRPV4 (TRPV4) Antikörper

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anti-Human TRPV4 Antikörper:

anti-Mouse (Murine) TRPV4 Antikörper:

anti-Rat (Rattus) TRPV4 Antikörper:

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Am meisten referenzierte anti-TRPV4 Antikörper

  1. Mouse (Murine) Polyclonal TRPV4 Primary Antibody für IHC, WB - ABIN351282 : Arniges, Fernuandez-Fernuandez, Albrecht, Schaefer, Valverde: Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking. in The Journal of biological chemistry 2006 (PubMed)
    Zeige alle 6 Referenzen für 351282

  2. Human Polyclonal TRPV4 Primary Antibody für ICC, IF - ABIN259364 : Butenko, Dzamba, Benesova, Honsa, Benfenati, Rusnakova, Ferroni, Anderova: The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia. in PLoS ONE 2012 (PubMed)
    Zeige alle 4 Referenzen für 259364

  3. Cow (Bovine) Polyclonal TRPV4 Primary Antibody für IHC, WB - ABIN2776284 : Sampat, Dermksian, Oungoulian, Winchester, Bulinski, Ateshian, Hung: Applied osmotic loading for promoting development of engineered cartilage. in Journal of biomechanics 2013 (PubMed)

  4. Human Polyclonal TRPV4 Primary Antibody für IF (p), IHC (p) - ABIN873245 : Sakakibara, Sakakibara, Kusumoto, Takeda, Hasegawa, Akashi, Minamikawa, Hashikawa, Terashi, Komori et al.: Upregulated Expression of Transient Receptor Potential Cation Channel Subfamily V Receptors in Mucosae of Patients with Oral Squamous Cell Carcinoma and Patients with a History of Alcohol Consumption ... in PLoS ONE 2017 (PubMed)

Weitere Antikörper gegen TRPV4 Interaktionspartner

Zebrafish Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) Interaktionspartner

  1. TRPP2 and TRPV4 are mechanosensitive channels in the endocardium.Oscillatory flow modulates mechanosensitive klf2a expression through trpv4 and trpp2 during heart valve development.

  2. TRPP2 utilizes TRPV4 to form a mechano- and thermosensitive molecular sensor in the cilium.

  3. Age-dependence of heat-activated seizure susceptibility mimicks the mRNA expression of TRPV4 and glutamate (zeige GRIN2A Antikörper) receptors.

  4. TRPV4 present in all sensory organs of adult zebrafish.

  5. Study reports cloning of a zebrafish trpv4 cDNA and assaying its expression during embryogenesis; trpv4 is expressed as maternal mRNA in 4-cell embryos and later zygotic expression is first observed in the forming notochord at the one somite stage.

  6. OS-9 (zeige OS9 Antikörper) regulates the secretory transport of TRPV4 and appears to protect TRPV4 subunits from the precocious ubiquitination and ER-associated degradation.

Human Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) Interaktionspartner

  1. A novel TRPV4 mutation implicating TRPV4 and altered calcium homeostasis in the pathogenesis of osteonecrosis was identified while reinforcing the importance of TRPV4 in bone diseases and vascular endothelium.

  2. both TRPV2 (zeige TRPV2 Antikörper) and TRPV4 are involved in migration of human cardiac c-kit (zeige KIT Antikörper)(+) progenitor cells.

  3. Data show that arylalkymine N-acetyltransferase (AANAT (zeige AANAT Antikörper)) levels and melatonin synthesis change after transient receptor potential channel 4 (zeige TRPC4 Antikörper) (TRPV4 channel) stimulation in ciliary body epithelial cells .

  4. TRPV4-induced calcium mobilization and inflammatory responses were enhanced in cystic fibrosis transmembrane conductance regulator (zeige CFTR Antikörper)-deficient cellular models.

  5. direct electrophysiological and pharmacological evidence for both TRPV4 and L-type Ca2 (zeige CA2 Antikörper)+ conductances, as well as a tetraethylammonium (TEA)- and paxilline-sensitive K+ conductance in human pulmonary fibroblasts.

  6. We demonstrate that pharmacological activation or inhibition of TRPV4 regulates Ca(2 (zeige CA2 Antikörper)+)-wave propagation from head to tail. Such findings may have wide application in male fertility-infertility, contraception and conservation of endangered species as well.

  7. These results confirm the function of TRPV4 in human cultured adipocytes and its regulation by insulin (zeige INS Antikörper).

  8. Helicobacter pylori infection-dependent DNA methylation (zeige HELLS Antikörper) suppressed TRPV4 expression in human gastric epithelia, suggesting that TRPV4 methylation may be involved in Helicobacter pylori-associated dyspepsia.

  9. Phorbol myristate acetate increased TRPV4 expression in U937 and THP-1 cells. (zeige PPARG Antikörper) There was no significant difference in TRPV4 expression in the nLDL group but a significant reduction in TRPV4 expression was detected in the oxLDL group.

  10. TRPV4 rs6606743 SNP was found to significantly contribute to the development of osmotic airway hyperresponsiveness in response to the decrease in osmolarity under inspiration of distilled water aerosol was studies in 189 patients with uncontrolled bronchial asthma, prevalence of AG + GG genotype frequency in the group of patients with asthma with osmotic hyperresponsiveness

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) Interaktionspartner

  1. Study found that hypotonicity in the portal circulation, probably sensed by TRPV4 channels, triggers the osmopressor response and intact renal nerves are needed for the full response.

  2. Altogether, these data identify a novel reciprocal functional link between TRPV4 activation and TGFbeta1 (zeige TGFB1 Antikörper) signals regulating dermal myofibroblast differentiation. These findings suggest that therapeutic inhibition of TRPV4 activity may provide a targeted approach to the treatment of scleroderma.

  3. Dynamic coupling between TRPV4 and Ca(2 (zeige CA2 Antikörper)+)-activated SK1 (zeige SPHK1 Antikörper)/3 and IK1 (zeige KCNN4 Antikörper) K(+) channels plays a critical role in regulating the K(+)-secretory BK channel KCNMA1 (zeige KCNMA1 Antikörper) in kidney collecting duct cells.

  4. TRPV4 channels are important for bladder afferent signaling. TRPV4 -/- mice bladders generate more noxious sensory output, which is predominantly mediated through TRPV1 (zeige TRPV1 Antikörper) expressing high threshold nerve fibers.

  5. TRPV4 does not play a major role in the kidney or is efficiently compensated when deleted. TRPV4 is critical for the release of vasopressin (zeige AVP Antikörper), the sensation of thirst, and the central osmoregulation.

  6. These results suggest that the Na(+) signal generated in Nax (zeige SCN7A Antikörper)-positive glial cells leads to the activation of TRPV4-positive neurons in sCVOs to stimulate water intake by using EETs as gliotransmitters.

  7. TRPV4 plays a critical role in the transduction of mechanical forces and gets activated by cell swelling and surface expansion.

  8. The absence of TRPV4-ATP-mediated effects on C-fibers indicates a distinct neurobiology for this ion channel and implicates TRPV4 as a novel therapeutic target for neuronal hyperresponsiveness in the airways and symptoms, such as cough.

  9. Here we analyzed sperm motility function of Trpv4 knockout (KO) mouse in temperature-gradient conditions to elucidate the thermotaxis of mouse sperm and the involvement of TRPV4 in thermotaxis. Large numbers of wild-type (WT) mouse sperm migrated into the high level of the temperature gradient, and thermotaxis was confirmed. The ratio of migrated sperm at the high temperature level was decreased in the KO sperm.

  10. TRPV4 is expressed in mouse and rat gastric epithelium and contributes to ATP release and gastric emptying.

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) Interaktionspartner

  1. Data indicate a physiologic function of transient receptor potential vanilloid 4 (TRPV4) in the regulation of blood-cerebrospinal fluid barrier (BCSFB) permeability.

  2. Hyposmotic shock-induced TRPV4 channel activation regulates hemichannel-mediated ATP release and Na-K-ATPase (zeige ATP1A1 Antikörper) activity in lens epithelium.

  3. The large amounts of transported calcium and the short signaling ways suggest a potentially important role of TRPV4 in many physiological processes.

  4. TRPV4 is present in articular chondrocytes in swine, and chondrocyte response to hypo-osmotic stress is mediated by this channel, which involves both an extracellular Ca(2 (zeige CA2 Antikörper)+) and intracellular Ca(2 (zeige CA2 Antikörper)+) release.

Cow (Bovine) Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) Interaktionspartner

  1. TRPV4 channels activity in bovine articular chondrocytes are regulated by obesity-associated mediators.

  2. TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.

TRPV4 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TRPV4

  • transient receptor potential cation channel, subfamily V, member 4 (trpv4) Antikörper
  • transient receptor potential cation channel, subfamily V, member 4 (TRPV4) Antikörper
  • transient receptor potential cation channel, subfamily V, member 4 (LOC100220808) Antikörper
  • transient receptor potential cation channel, subfamily V, member 4 (Trpv4) Antikörper
  • 0610033B08Rik Antikörper
  • CMT2C Antikörper
  • HMSN2C Antikörper
  • Otrpc4 Antikörper
  • SMAL Antikörper
  • SPSMA Antikörper
  • SSQTL1 Antikörper
  • Trp12 Antikörper
  • VR-OAC Antikörper
  • VRL-2 Antikörper
  • VRL2 Antikörper
  • Vroac Antikörper
  • wu:fp52e02 Antikörper

Bezeichner auf Proteinebene für TRPV4

transient receptor potential cation channel subfamily V member 4 , transient receptor potential cation channel, subfamily V, member 4 , transient receptor potential cation channel subfamily V member 4-like , OSM9-like transient receptor potential channel 4 , osm-9-like TRP channel 4 , osmosensitive transient receptor potential channel 4 , transient receptor potential protein 12 , vanilloid receptor-like channel 2 , vanilloid receptor-related osmotically activated channel , vanilloid receptor-like protein 2 , vanilloid receptor-related osmotically-activated channel , VR-OAC , transient receptor potential cation channel, subfamily 5, member 4 , vanilloid receptor-related osmotically activated channel (Vroac) , vanilloid receptor-related osmotically activated channel protein

GENE ID SPEZIES
557850 Danio rerio
709605 Macaca mulatta
100458589 Pongo abelii
100472561 Ailuropoda melanoleuca
100539676 Meleagris gallopavo
100590720 Nomascus leucogenys
100220808 Taeniopygia guttata
59341 Homo sapiens
63873 Mus musculus
66026 Rattus norvegicus
395427 Gallus gallus
486308 Canis lupus familiaris
100126845 Sus scrofa
540259 Bos taurus
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