anti-Islet Amyloid Polypeptide (IAPP) Antikörper

anti-Islet Amyloid Polypeptide Antikörper (IAPP)
Auf finden Sie aktuell 118 Islet Amyloid Polypeptide (IAPP) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Islet Amyloid Polypeptide Kits (78) und Islet Amyloid Polypeptide Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 240 Islet Amyloid Polypeptide Produkte verfügbar.
Amylin, DAP, IAP, LOC100230121

Meistgesuchte Reaktivitäten zu anti-Islet Amyloid Polypeptide (IAPP) Antikörper

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Am meisten referenzierte anti-Islet Amyloid Polypeptide Antikörper

  1. Human Monoclonal IAPP Primary Antibody für IHC (fro), IF - ABIN118954 : Gong, Liu, Zeng, Peng, Chen, Zhou, Li: Amylin deposition in the kidney of patients with diabetic nephropathy. in Kidney international 2007 (PubMed)
    Zeige alle 7 Referenzen für 118954

  2. Human Monoclonal IAPP Primary Antibody für ICC, IHC (fro) - ABIN153560 : Nakamura, Okabayashi, Ageyama, Koie, Sankai, Ono, Fujimoto, Terao: Transthyretin amyloidosis and two other aging-related amyloidoses in an aged vervet monkey. in Veterinary pathology 2008 (PubMed)
    Zeige alle 6 Referenzen für 153560

  3. Cat (Feline) Polyclonal IAPP Primary Antibody für IHC (fro), IHC (p) - ABIN115737 : Mulder, Ahrén, Stridsberg, Sundler: Non-parallelism of islet amyloid polypeptide (amylin) and insulin gene expression in rats islets following dexamethasone treatment. in Diabetologia 1995 (PubMed)
    Zeige alle 2 Referenzen für 115737

  4. Dog (Canine) Polyclonal IAPP Primary Antibody für WB - ABIN610646 : Cifuentes-Diaz, Frugier, Tiziano, Lacène, Roblot, Joshi, Moreau, Melki: Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophy. in The Journal of cell biology 2001 (PubMed)
    Zeige alle 2 Referenzen für 610646

Weitere Antikörper gegen Islet Amyloid Polypeptide Interaktionspartner

Human Islet Amyloid Polypeptide (IAPP) Interaktionspartner

  1. Data suggest that single aromatic/hydrophobic amino acid residues within IAPP (islet amyloid polypeptide) amyloid core region are able to control its interaction with amyloid-beta(1-40) or amyloid-beta(1-42) but not IAPP self-assembly; four aromatic/hydrophobic residues are able to control both IAPP amyloid self-assembly and its cross-interaction with amyloid-beta(1-40) or amyloid-beta(1-42).

  2. Data show that aluminum (Al3+) could inhibit islet amyloid polypeptide hIAPP(11-28) fibrillogenesis.

  3. The absence of BACE2 (zeige BACE2 Antikörper) ameliorates glucose tolerance defects induced by IAPP overexpression in the beta-cell and promotes beta-cell survival.

  4. This study supports the elucidation of the structural basis of IAPP amyloid formation and highlights the extent of amyloid fibril polymorphism.

  5. Data suggest that a single GlcNAc residue at CTR (zeige CALCR Antikörper) N130 (asparagine 130) is responsible for enhanced affinity of calcitonin (zeige CALCA Antikörper) for CTR (zeige CALCR Antikörper) ECD (zeige SHFM1 Antikörper); the same appears to apply for enhanced affinity of amylin for RAMP2 (zeige RAMP2 Antikörper)-CTR (zeige CALCR Antikörper) ECD (zeige SHFM1 Antikörper). [GlcNAc = N-acetylglucosamine; CTR (zeige CALCR Antikörper) = calcitonin receptor (zeige CALCR Antikörper); ECD (zeige SHFM1 Antikörper) = extracellular domain; RAMP2 (zeige RAMP2 Antikörper) = receptor (calcitonin) activity modifying protein 2 (zeige RAMP2 Antikörper)].

  6. The kinetics of human amylin amyloid formation can be monitored by SYPRO-orange fluorescence and match the time course determined with thioflavin-T assays.

  7. effect of cholesterol on the amyloidogenicity of IAPP

  8. Chondroitin sulfate A has an intensive promotion effect on the fibrillation of human IAPP at the palmitoyloleoylphosphatidylcholine (POPC) membrane, which is larger than the total effect of Chondroitin sulfate A alone and POPC alone.

  9. C4BP (zeige C4BPA Antikörper) protects beta-cells from IAPP cytotoxicity by modulating IAPP fibril formation extracellularly and also, after uptake by the cells, by enhancing cholesterol synthesis.

  10. beta-hairpin peptide inhibitor of IAPP aggregation that are stabilized in that conformation, or even forced to remain in the hairpin conformation by a backbone cyclization constraint, display superior activity as inhibitors.

Pig (Porcine) Islet Amyloid Polypeptide (IAPP) Interaktionspartner

Mouse (Murine) Islet Amyloid Polypeptide (IAPP) Interaktionspartner

  1. These data suggest participation by both soluble and fibrillar aggregates in IAPP-induced islet inflammation. IAPP-induced activation of TLR2 (zeige TLR2 Antikörper) and secretion of IL-1 (zeige IL1A Antikörper) may be important therapeutic targets to prevent amyloid-associated beta cell dysfunction.

  2. Hypothalamic amylin is transcriptionally regulated by leptin (zeige LEP Antikörper), that it can act directly on ObRb (zeige LEPR Antikörper) neurons in concert with leptin (zeige LEP Antikörper), and that it regulates feeding.

  3. Matrix Metalloproteinase-9 (zeige MMP9 Antikörper) Protects Islets from Amyloid-induced Toxicity.

  4. Data indicate that T-cell receptors that react to chromogranin A (ChgA (zeige CHGA Antikörper)) and islet amyloid polypeptide precursor (IAPP) autoantigens were impaired when the thymic stromal cells lacked thymus-specific serine protease (TSSP (zeige PRSS16 Antikörper)).

  5. Study the physiologic actions of IAPP on pancreatic beta cells, which secrete this peptide together with insulin (zeige INS Antikörper) upon glucose stimulation. Explore the signaling pathways and mitogenic actions of IAPP on beta cells.

  6. deletion of the DeltaN isoforms of p63 (zeige CKAP4 Antikörper) or p73 (zeige ARHGAP24 Antikörper) leads to metabolic reprogramming and regression of p53 (zeige TP53 Antikörper)-deficient tumours through upregulation of IAPP, the gene that encodes amylin, a 37-amino-acid peptide co-secreted with insulin (zeige INS Antikörper) by the beta cells of the pancreas

  7. The stability, conformational dynamics and association force of different single-layer models of the full-length wild-type and glycine mutants of amylin, were investigated.

  8. studies have identified a novel TXNIP (zeige TXNIP Antikörper)/miR (zeige MLXIP Antikörper)-124a/FoxA2 (zeige FOXA2 Antikörper)/IAPP signaling cascade linking the critical beta-cell signaling pathways of TXNIP (zeige TXNIP Antikörper) and IAPP

  9. MMP-9 (zeige MMP9 Antikörper) constitutes an endogenous islet protease that limits islet amyloid deposition and its toxic effects via degradation of hIAPP.

  10. Data suggest that amylin and leptin (zeige LEP Antikörper) play additive roles in regulating energy homeostasis via activation of overlapping signalling pathways; mechanisms may be different in hypothalamus, muscle, and liver and in cases of endoplasmic reticulum stress.

Islet Amyloid Polypeptide (IAPP) Antigen-Profil

Beschreibung des Gens

Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.

Alternative names and synonyms associated with Islet Amyloid Polypeptide (IAPP)

  • islet amyloid polypeptide (LOC100230121) Antikörper
  • islet amyloid polypeptide (IAPP) Antikörper
  • islet amyloid polypeptide (Iapp) Antikörper
  • islet amyloid polypeptide-like (LOC100520838) Antikörper
  • Amylin Antikörper
  • DAP Antikörper
  • IAP Antikörper
  • LOC100230121 Antikörper

Bezeichner auf Proteinebene für IAPP

islet amyloid polypeptide , Islet amyloid polypeptide (diabetes-associated peptide; amylin) , amylin , diabetes-associated peptide , insulinoma amyloid peptide , DAP , amyloid protein

100230121 Taeniopygia guttata
3375 Homo sapiens
751513 Felis catus
100381251 Sus scrofa
24476 Rattus norvegicus
100135550 Cavia porcellus
15874 Mus musculus
100009489 Oryctolagus cuniculus
403909 Canis lupus familiaris
100138011 Bos taurus
101120402 Ovis aries
396362 Gallus gallus
101832022 Mesocricetus auratus
100520838 Sus scrofa
Ausgewählte Anbieter für anti-Islet Amyloid Polypeptide (IAPP) Antikörper
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