anti-Ratte (Rattus) p65 Antikörper für Enzyme Immunoassay

Recommended p65 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Nuclear Factor-KB P65 (NFkBP65) Antikörper
  • NFKB3
  • p65
  • NFkB
  • v-rel avian reticuloendotheliosis viral oncogene homolog A
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian)
  • RELA
  • Rela
Epitop
Ser536
146
84
68
63
51
49
44
41
40
37
33
26
26
23
18
17
16
15
15
13
13
13
12
11
10
9
9
8
6
6
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
1245
681
521
73
59
55
31
30
28
26
15
8
8
6
5
4
2
1
1
Wirt
Kaninchen
1074
148
17
16
11
1
Klonalität
Polyklonal
Konjugat
Dieser p65 Antikörper ist unkonjugiert
34
34
26
21
19
18
16
16
13
13
13
9
9
9
9
9
9
8
8
4
4
3
3
3
2
2
2
2
2
2
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
912
459
359
268
237
159
118
92
84
28
21
19
18
12
11
6
6
6
6
5
4
2
2
1
Hersteller
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Produktnummer ABIN318869
363,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5551725 EIA IHC (p) WB Rabbit IgG Ser536 Anmelden zum Anzeigen Polyclonal
1 ABIN303222 EIA IHC (p) WB Rabbit Ser536 Anmelden zum Anzeigen Polyclonal
1 ABIN5556626 EMSA EIA IP WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN303336 EIA IHC (p) IP WB Rabbit pSer529 Anmelden zum Anzeigen Polyclonal

General

Antigen Nuclear Factor-KB P65 (NFkBP65) Antikörper
Epitop Ser536
(146), (84), (68), (63), (51), (49), (44), (41), (40), (37), (33), (26), (26), (23), (18), (17), (16), (15), (15), (13), (13), (13), (12), (11), (10), (9), (9), (8), (6), (6), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(1245), (681), (521), (73), (59), (55), (31), (30), (28), (26), (15), (8), (8), (6), (5), (4), (2), (1), (1)
Wirt Kaninchen
(1074), (148), (17), (16), (11), (1)
Klonalität
Polyklonal
Konjugat Dieser p65 Antikörper ist unkonjugiert
(34), (34), (26), (21), (19), (18), (16), (16), (13), (13), (13), (9), (9), (9), (9), (9), (9), (8), (8), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(912), (459), (359), (268), (237), (159), (118), (92), (84), (28), (21), (19), (18), (12), (11), (6), (6), (6), (6), (5), (4), (2), (2), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p65 Antikörper

Target Details p65 Anwendungsinformationen Handhabung ProductDetails: References for anti-p65 antibody (ABIN318869) Bilder
Spezifität This antibody detects the p65 (RelA) subunit of nuclear factor kappa-B (NFkappaB) when phosphorylated at serine 536.
Kreuzreaktivität (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Reinigung Purified
Immunogen Synthetic peptide corresponding to residues surrounding serine 536 of Human NFkB p65 protein.
Isotyp IgG

Target Details p65

Produktdetails anti-p65 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-p65 antibody (ABIN318869) Bilder zurück nach oben
Antigen
Andere Bezeichnung RELA / NF-kB p65 (NFkBP65 Antibody Abstract)
Hintergrund NFkappaB is a heterodimeric DNA binding protein which was originally identified consisting of p65 and p50 (NF?B1) subunits. Research has led to the discovery of other subunits, including p52 (NFkappaB2), cRel, and RelB. NFkappaB is ubiquitously expressed, and functions as a second messenger which upon activation leads to the transcription of a number of genes. NFkappaB is activated by a number of agents, including pro-inflammatory cytokines and bacterial lipopolysaccharide, and is essential for the maturation of T cells and regulation of their survival and activation. Phosphorylation of serine 536 contributes to NFkappaB transactivation and increases p65 transcription activity.Synonyms: NF kappa B p65, NFKB3, NFkB p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, Rel A, Transcription factor p65
Gen-ID 5970
NCBI Accession NP_001138610
UniProt Q04206
Pathways NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-p65 Antikörper Target Details p65 Handhabung ProductDetails: References for anti-p65 antibody (ABIN318869) Bilder zurück nach oben
Applikationshinweise Western Blot: 1: 100 - 1: 1000, detects a band of approximately 65 kDa in the appropriate celllysate. Immunohistochemistry on paraffin sections: 1: 50 - 1: 250. ELISA: 1: 500 - 1: 3000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p65 Antikörper Target Details p65 Anwendungsinformationen ProductDetails: References for anti-p65 antibody (ABIN318869) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

ProductDetails: References for anti-p65 antibody (ABIN318869)

Produktdetails anti-p65 Antikörper Target Details p65 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Mattioli, Sebald, Bucher, Charles, Nakano, Doi, Kracht, Schmitz: "Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 10, pp. 6336-44, 2004