anti-GLI2 (GLI2) Antikörper

Bezeichnung:
anti-GLI Family Zinc Finger 2 Antikörper (GLI2)
Auf www.antikoerper-online.de finden Sie aktuell 96 GLI Family Zinc Finger 2 (GLI2) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen GLI2 Kits (6) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 106 GLI2 Produkte verfügbar.
Synonyme:
AW546128, GLI2/GLI4, GLI3, HPE9, THP1, THP2

Meistgesuchte Reaktivitäten zu anti-GLI2 (GLI2) Antikörper

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anti-Human GLI2 Antikörper:

anti-Rat (Rattus) GLI2 Antikörper:

anti-Mouse (Murine) GLI2 Antikörper:

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Am meisten referenzierte anti-GLI2 Antikörper

  1. Human Polyclonal GLI2 Primary Antibody für IHC, WB - ABIN2777474 : Ikram, Neill, Regl, Eichberger, Frischauf, Aberger, Quinn, Philpott: GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter. in The Journal of investigative dermatology 2004 (PubMed)
    Zeige alle 24 Referenzen für 2777474

  2. Human Polyclonal GLI2 Primary Antibody für ChIP, ELISA - ABIN269891 : Won, Kim, Lim, Sung, Kim, Park, Lee, Choi: Autophagy is related to the hedgehog signaling pathway in human gastric adenocarcinoma: prognostic significance of Beclin-1 and Gli2 expression in human gastric adenocarcinoma. in Pathology, research and practice 2015 (PubMed)
    Zeige alle 3 Referenzen für 269891

  3. Human Polyclonal GLI2 Primary Antibody für ICC, IF - ABIN4314278 : Martinez, Kobayashi, Krishnan, Webber, Christie, Guo, Singh, Zochodne: Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen. in Experimental neurology 2015 (PubMed)

  4. Human Polyclonal GLI2 Primary Antibody für ELISA, IHC - ABIN251273 : Haycraft, Banizs, Aydin-Son, Zhang, Michaud, Yoder: Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. in PLoS genetics 2005 (PubMed)

  5. Human Polyclonal GLI2 Primary Antibody für IHC, ELISA - ABIN1043881 : Roessler, Ermilov, Grange, Wang, Grachtchouk, Dlugosz, Muenke: A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2. in Human molecular genetics 2005 (PubMed)

Weitere Antikörper gegen GLI2 Interaktionspartner

Human GLI Family Zinc Finger 2 (GLI2) Interaktionspartner

  1. studies identify a novel molecular mechanism of regulation of CD40L (zeige CD40LG Antikörper) by the transcription factor GLI2 in the tumor microenvironment downstream of CCR3 (zeige CCR3 Antikörper) signaling

  2. the data suggest that CCRK (zeige CDK20 Antikörper) positively regulates the kinetics by which ciliary proteins such as Smoothened (zeige SMO Antikörper) and Gli2 are imported into the cilium, and that the efficiency of ciliary recruitment allows for potent responses to Hedgehog (zeige SHH Antikörper) signaling over long time periods.

  3. GLI2 is a regulator of beta-catenin (zeige CTNNB1 Antikörper) and provides insights into its role in tumorigenesis.

  4. bioinformatics analysis and luciferase reporter assay predicted the direct binding to miR (zeige MLXIP Antikörper)-125b-5p, which has been reported to function as a tumor suppressor in osteosarcoma. Furthermore, functional experiments validated that cir (zeige KCNJ5 Antikörper)-GLI2 exerted the tumor-promoting effects on osteosarcoma cells via negatively targeting miR (zeige MLXIP Antikörper)-125b-5p.

  5. GANT61, which is a targeted inhibitor of Gli1 (zeige GLI1 Antikörper) and Gli2, decreased cell viability and promoted cell apoptosis. Thus, TGF-b1 induced EMT (zeige ITK Antikörper) in neuroblastoma (zeige ARHGEF16 Antikörper) cells to increase their migration. Specifically, EMT (zeige ITK Antikörper) induced by TGF-b1 in neuroblastoma (zeige ARHGEF16 Antikörper) cells did not depend on the Smad (zeige SMAD1 Antikörper) signaling pathway, and the transcription factor Gli (zeige GLI1 Antikörper) participated in TGF-b1-induced EMT (zeige ITK Antikörper) independent of Smad (zeige SMAD1 Antikörper) signaling.

  6. These results demonstrate that miR (zeige MLXIP Antikörper)-124 is an important downstream target gene of Hh signaling, and the Gli2/miR (zeige MLXIP Antikörper)-124/AURKA (zeige AURKA Antikörper) axis is essential for the proliferation and growth of human glioma cells.

  7. in trophoblasts, GLI2 not only directly bound to the promoter region of gene hsd11b2 (zeige HSD11B2 Antikörper) to transactivate hsd11b2 (zeige HSD11B2 Antikörper) but also formed a heterodimer with RNA polymerase II, resulting in up-regulation of hsd11b2 (zeige HSD11B2 Antikörper) gene transcription

  8. GLI2 was identified as a crucial downstream mediator of the pro-fibrotic effects of TGF-beta (zeige TGFB1 Antikörper).

  9. Gli1 and Gli2 exhibited different functions in the regulation of p63 expression or proliferation of p63(+) cells in Kras-AR driven tumors.

  10. this study shows that Gli2 expression was more often positive in advanced non-small-cell lung carcinoma patients refractory to platinum-based chemotherapy

Cow (Bovine) GLI Family Zinc Finger 2 (GLI2) Interaktionspartner

  1. Data indicate that the expression levels of transcription factors Gli1 (zeige GLI1 Antikörper) and Gli2 in muscle were the lowest of the 13 tissues.

Pig (Porcine) GLI Family Zinc Finger 2 (GLI2) Interaktionspartner

  1. The 12 SNPs of GLI2 encompassing exon 4 to exon 8 showed strong association with in the anorectal atresia in pigs.

Mouse (Murine) GLI Family Zinc Finger 2 (GLI2) Interaktionspartner

  1. studies identify a novel molecular mechanism of regulation of CD40L (zeige CD40LG Antikörper) by the transcription factor GLI2 in the tumor microenvironment downstream of CCR3 (zeige CCR3 Antikörper) signaling

  2. Sufu (zeige SUFUH Antikörper) is upregulated in active Shh (zeige SHH Antikörper) responding tissues and accompanies Gli (zeige GLI1 Antikörper) activators translocating into and Gli (zeige GLI1 Antikörper) repressors out of the nucleus.

  3. Gli2+/-;Gli3Delta699/+ mice can serve as a genetic mouse model for common DSD (zeige FADS1 Antikörper).

  4. Despite increased production of full-length GLI2 and GLI3 (zeige GLI3 Antikörper) isoforms, previously identified GLI (zeige GLI1 Antikörper) targets important for mandibular and glossal development (Foxf1 (zeige FOXF1 Antikörper), Foxf2 (zeige FOXF2 Antikörper), Foxd1 (zeige FOXD1 Antikörper) and Foxd2 (zeige FOXD2 Antikörper)) were transcriptionally downregulated in Kif3a (zeige KIF3A Antikörper)(f/f);Wnt1 (zeige WNT1 Antikörper)-Cre embryos.

  5. Gli1 and Gli2 exhibited different functions in the regulation of p63 expression or proliferation of p63(+) cells in Kras-AR driven tumors.

  6. the GLI2 protein level could serve as a feasible marker of ligand-dependent hedgehog (zeige SHH Antikörper) activation in pancreatic neoplasms.

  7. Study suggested that loss of Gli2 mRNA mediated the anterior-restricted defect in conditional Dicer (zeige DICER1 Antikörper) knockdown mice and showed that miR (zeige MLXIP Antikörper)-106b positively regulated Gli2 mRNA expression

  8. Sufu (zeige SUFUH Antikörper) deletion early in embryogenesis resulted in unstable Gli2 and Gli3 (zeige GLI3 Antikörper) activity, leading to the ectopic activation of Shh (zeige SHH Antikörper) signaling.

  9. the three GLI (zeige GLI1 Antikörper) factors(GLI1 (zeige GLI1 Antikörper), GLI2, and GLI3 (zeige GLI3 Antikörper)) in mature hepatocytes form an interactive transcriptional network that is involved in the control of target genes associated with metabolic zonation as well as with lipid and drug metabolism

  10. Gli2 protein expression is downregulated during neural tube patterning, regulating Shh (zeige SHH Antikörper) signaling. Shh (zeige SHH Antikörper)-induced upregulation of Gli2 transcription prevents Gli (zeige GLI1 Antikörper) activity levels from adapting in a different cell type.

GLI2 Antigen-Profil

Beschreibung des Gens

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Alternative names and synonyms associated with GLI2

  • GLI-Kruppel family member GLI2 (LOC100359289) Antikörper
  • GLI family zinc finger 2 (GLI2) Antikörper
  • GLI family zinc finger 2 (Gli2) Antikörper
  • GLI-Kruppel family member GLI2 (Gli2) Antikörper
  • AW546128 Antikörper
  • GLI2/GLI4 Antikörper
  • GLI3 Antikörper
  • HPE9 Antikörper
  • THP1 Antikörper
  • THP2 Antikörper

Bezeichner auf Proteinebene für GLI2

GLI-Kruppel family member GLI2 , glioma-associated oncogene family zinc finger 2 , oncogene GLI2 , tax helper protein 1 , tax helper protein 2 , tax-responsive element-2 holding protein , tax-responsive element-25-bp sequence binding protein , zinc finger protein GLI2 , Zn finger transcription factor , zinc finger protein GLI3 , Tax helper protein

GENE ID SPEZIES
100359289 Oryctolagus cuniculus
2736 Homo sapiens
304729 Rattus norvegicus
459582 Pan troglodytes
510255 Bos taurus
395956 Gallus gallus
100682984 Canis lupus familiaris
100520334 Sus scrofa
14633 Mus musculus
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