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anti-Mouse (Murine) ESM1 Antikörper:
anti-Rat (Rattus) ESM1 Antikörper:
anti-Human ESM1 Antikörper:
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Human Monoclonal ESM1 Primary Antibody für IHC (p), ELISA - ABIN564812
Liu, Zhang, Du, Hu, Zhang, Wang, Li, Ji: Overexpression of endothelial cell specific molecule-1 (ESM-1) in gastric cancer. in Annals of surgical oncology 2010
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Rat (Rattus) Polyclonal ESM1 Primary Antibody für ICC, IHC - ABIN1175699
Zhao, Xue, Guo, Sun, Liu, Wang: Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension. in International immunopharmacology 2016
glomerular-derived Esm-1 as a potential non-invasive biomarker of diabetic nephropathy
Results reveal a novel pathway for endocan in the control of tumor growth, which involves inflammatory cells of the innate immunity.
Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.
This study shows endocan can elicit severe inflammatory responses and inhibiting endocan release offers a potential strategy for treating sepsis.
endocan is normally present in the mouse brain and prior vascular perfusion with FITC may provide a useful tool for identify newly forming blood vessels.
Mouse endocan serum level was measured at a median of 0.96 ng/mL and 1.08 ng/mL in 129Sv mice and C57bl6, respectively.
A paracrine vasoregulatory pathway mediated by endothelial cell-derived ET-1 (zeige EDN1 Antikörper) acting on the vascular smooth muscle ET(A (zeige EDNRA Antikörper)) receptor.
Results suggest that endocan (ESM-1)is preferentially expressed in tumor endothelium in vivo and that its expression is regulated by tumor-derived factors.
Endocan expression was correlated with poor clinical outcomes in patients with Pancreatic Neuroendocrine Tumors . The results indicated that endocan expression may be a reliable marker for predicting tumor recurrence in patients with PNETs.
Physical activity increases circulating endocan level.
These findings provide the first evidence that the imbalance of MMP-9 (zeige MMP9 Antikörper)/TIMP-1 (zeige TIMP1 Antikörper), is one of the regulation mechanisms by which ESM1 promotes tumorigenicity and metastasis of prostate cancer cells.
These results are consistent with the view that endocan measured in ICU patients is intact, stable, and accurate. Then, the low endocan level observed in ICU patients who developed acute respiratory distress syndrome is likely to be reliable.
Dopamine agonist resistance-related ESM1 promotes the angiogenesis and tumor cells growth of prolactinomas, suggesting that ESM1 may be a novel therapeutic target for prolactinomas.
These results suggest human cytomegalovirus infection leads to glioma progression through an upregulation of endocan and the secretion of inflammatory cytokines.
Endocan-expressing microvessel density significantly correlates with the expression of VEGF (zeige VEGFA Antikörper) and VEGFR2 (zeige KDR Antikörper) and is a valuable prognostic factor for survival in human gastric cancer.
Circulating P-selectin (zeige SELP Antikörper) levels were closely associated with endocan levels in obese children and adolescents with non-alcoholic fatty liver disease.
this study shows that endocan may play an important role in the development of connective tissue disease related pulmonary arterial hypertension
This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.
endothelial cell-specific molecule 1
, ESM-1 secretory protein
, pineal specific PG25 protein