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Lv, Wang, Li, Wang, Li, Lv, Fu, Hu: Rupatadine protects against pulmonary fibrosis by attenuating PAF-mediated senescence in rodents. in PLoS ONE 2013
Show all 15 Pubmed References
Functional loss of glucocerebrosidase (zeige GBA ELISA Kits) or beta-Gal promotes toxic conversion of alphaSyn via aberrant interactions between alphaSyn and their substrate glycolipids, leading to aggravation of alphaSyn-mediated neurodegeneration.
beta-Gal expression in articular cartilage is associated with progressive knee osteoarthritis joint damage and is a potential indictor of disease severity.
This study shows that moderate widespread expression of betagal in the CNS of GM1 gangliosidosis mice is sufficient to achieve significant biochemical impact with phenotypic amelioration and extension in lifespan
The study proposes an explanation for ELNR1 uncoupling based on the age-related alterations of Neu-1 (zeige NEU1 ELISA Kits) activity.
Overexpression of the novel senescence marker GLB1 in prostate cancer predicts reduced recurrence of PSA-expressing tumors.
Identification and analysis of GLB1 mutations in Indian patients with GM1 gangliosidosis.
We observed significant lower values of beta-galactosidase, FUC and tendency to decrease of MAN and GLU (zeige DCTN1 ELISA Kits) concentration in nasal polyps
This study analyzed patient cells with GM1 gangliosidosis and sialidosis. A novel mutation p.E186A is identified in GLB1 gene.
The activity of serum GAL (zeige GAL ELISA Kits) was significantly higher in colon cancer patients with a history of alcohol and nicotine dependence.
beta-galactosidase, considered as a senescence marker, is over-expressed only in specific subtypes of pituitary adenomas, but is also present in carcinomas considered as a group
In the serum of patients with Lyme disease, GAL (zeige GAL ELISA Kits) activity significantly increased (p = 0.029), and the activity of FUC had a tendency to increase (p = 0.153), compared to the control group.
beta-gal is present in the pro-urine from where it is thought to stimulate TRPV5 (zeige TRPV5 ELISA Kits) activity.
Senescence-associated beta-galactosidase is present in apical vacuoles of visceral endoderm in developing mouse embryos.
We show here that mouse GLB1 has greater stability when compared to human GLB1, and that human GLB1 activity is temperature and protective-dependent on protein cathepsin A (zeige CTSA ELISA Kits), while that of mouse GLB1 is not
This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
, acid beta-galactosidase
, elastin receptor 1, 67kDa
, beta-galactosidase complex
, beta-galactosidase electrophoretic
, beta-galactosidase systemic regulator
, beta-galactosidase temporal
, lysosomal beta-galactosidase