anti-ABCC5 (ABCC5) Antikörper

Bezeichnung:
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 Antikörper (ABCC5)
Auf www.antikoerper-online.de finden Sie aktuell 94 ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ABCC5 Kits (5) und ABCC5 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 106 ABCC5 Produkte verfügbar.
Synonyme:
2900011L11Rik, ABC33, Abcc5a, Abcc5b, AI132311, EG636260, EST277145, Gm7175, MOAT-C, MOATC, Mrp5, pABC11, SMRP

Meistgesuchte Reaktivitäten zu anti-ABCC5 (ABCC5) Antikörper

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anti-Human ABCC5 Antikörper:

anti-Mouse (Murine) ABCC5 Antikörper:

anti-Rat (Rattus) ABCC5 Antikörper:

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Am meisten referenzierte anti-ABCC5 Antikörper

  1. Human Monoclonal ABCC5 Primary Antibody für IHC (fro), IF - ABIN1105175 : Borst, de Wolf, van de Wetering: Multidrug resistance-associated proteins 3, 4, and 5. in Pflügers Archiv : European journal of physiology 2007 (PubMed)
    Zeige alle 3 Referenzen für 1105175

  2. Human Monoclonal ABCC5 Primary Antibody für IHC (fro), IF - ABIN1105177 : Kool, de Haas, Scheffer, Scheper, van Eijk, Juijn, Baas, Borst: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. in Cancer research 1997 (PubMed)
    Zeige alle 2 Referenzen für 1105177

  3. Human Monoclonal ABCC5 Primary Antibody für IHC (fro), IF - ABIN1105176 : Scheffer, Kool, Heijn, de Haas, Pijnenborg, Wijnholds, van Helvoort, de Jong, Hooijberg, Mol, van der Linden, de Vree, van der Valk, Elferink, Borst, Scheper: Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. in Cancer research 2000 (PubMed)
    Zeige alle 2 Referenzen für 1105176

  4. Human Polyclonal ABCC5 Primary Antibody für IHC (p), IHC - ABIN409071 : Meyer Zu Schwabedissen, Grube, Heydrich, Linnemann, Fusch, Kroemer, Jedlitschky et al.: Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ... in The American journal of pathology 2005 (PubMed)

  5. Human Polyclonal ABCC5 Primary Antibody für FACS, IHC (p) - ABIN652519 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

Weitere Antikörper gegen ABCC5 Interaktionspartner

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5) Interaktionspartner

  1. These findings enrich the allelic spectrum of ABCC5 in PACG. We identified no tagging SNP responsible for the association of the whole region.

  2. Survivors of childhood acute lymphoblastic leukemia treated with doxorubicin with the ABCC5 TT-1629 genotype had an average of 8-12% reduction of ventricular ejection and shortening fractions.

  3. our work indicated that decreased SLC34A2 (zeige SLC34A2 Antikörper) expression sensitized BCSCs to doxorubicin via SLC34A2 (zeige SLC34A2 Antikörper)-Bmi1 (zeige BMI1 Antikörper)-ABCC5 signaling and shed new light on understanding the mechanism of chemoresistance in BCSCs. This study not only bridges the missing link between stem cell-related transcription factor (Bmi1 (zeige BMI1 Antikörper)) and ABC transporter (zeige ABCG2 Antikörper) (ABCC5) but also contributes to development of potential therapeutics against breast cancer.

  4. Deletions of ABCC5 predict good tumor response to neoadjuvant chemotherapy in breast cancer.

  5. genetic association study in population in Mexico: Data suggest SNPs in ABCC5 (3933+313T>C) are not associated with adverse reactions to methotrexate; they protect against myelosuppression in pediatric patients with ALL (acute lymphoblastic leukemia).

  6. We identified several genes (FasL (zeige FASL Antikörper), MSH2 (zeige MSH2 Antikörper), ABCC5, CASP3 (zeige CASP3 Antikörper), and CYP3A4 (zeige CYP3A4 Antikörper))that showed association with PFS in patients with osteosarcoma. These pharmacogenetic risk factors might be useful to predict treatment outcome

  7. ABCC5 is a general glutamate (zeige GRIN1 Antikörper) conjugate and analog transporter that affects the disposition of endogenous metabolites, toxins, and drugs.

  8. The present study investigated the time course and dose dependency of the induction of three efflux proteins, P-gp (zeige ABCB4 Antikörper), MRP1 (zeige MDM4 Antikörper) and MRP5, in response to gemcitabine exposure in Capan-2 pancreatic cancer cell line at transcriptional and translational levels.

  9. cCMP is a substrate for MRP5

  10. The blockade of ABC transporter (zeige ABCG2 Antikörper) MRP5 could help to improve drug effectiveness, reduce tumour growth and prevent recurrence in glioblastoma multiforme.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5) Interaktionspartner

  1. ABCC5 is a general glutamate (zeige GRIN1 Antikörper) conjugate and analog transporter that affects the disposition of endogenous metabolites, toxins, and drugs.

  2. Deficiency of MKP5 (zeige DUSP10 Antikörper) resulted in increased inflammatory activation in macrophages. These findings thus demonstrate that MKP5 (zeige DUSP10 Antikörper) critically controls inflammation in white adipose tissue and the development of metabolic disorders

  3. Reduced cGMP export as a consequence of decreased MRP5 expression can attenuate heart failure in sepsis.

ABCC5 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear.

Alternative names and synonyms associated with ABCC5

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5) Antikörper
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5) Antikörper
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 5 (Abcc5) Antikörper
  • immunoglobulin heavy variable 9-4 (Ighv9-4) Antikörper
  • 2900011L11Rik Antikörper
  • ABC33 Antikörper
  • Abcc5a Antikörper
  • Abcc5b Antikörper
  • AI132311 Antikörper
  • EG636260 Antikörper
  • EST277145 Antikörper
  • Gm7175 Antikörper
  • MOAT-C Antikörper
  • MOATC Antikörper
  • Mrp5 Antikörper
  • pABC11 Antikörper
  • SMRP Antikörper

Bezeichner auf Proteinebene für ABCC5

ATP-binding cassette sub-family C member 5 , canalicular multispecific organic anion transporter C , multi-specific organic anion transporter C , multidrug resistance-associated protein 5 , ATP-binding cassette, sub-family C (CFTR/MRP), member 5a , ATP-binding cassette, sub-family C (CFTR/MRP), member 5b , ATP-binding cassette, sub-family C, member 5 , MOAT-C , SMRP , ATP-binding cassette sub-family C (CFTR/MRP) member 5a , ATP-binding cassette, sub-family C (CFTR/MRP), member 5

GENE ID SPEZIES
10057 Homo sapiens
27416 Mus musculus
116721 Rattus norvegicus
636260 Mus musculus
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