Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) Proteine (Uchl3)

Auf www.antikoerper-online.de finden Sie aktuell 23 Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3) Proteine von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) Antikörper (119) und Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) Kits (1) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 146 Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) Produkte verfügbar.
Synonyme:
im:6908825, RGD1561196, UCH-6, UCH-L3, Uchl3, uchl4, zgc:109963
alle Proteine anzeigen Gen GeneID UniProt
Uchl3 114094  
Uchl3 7347 P15374
Uchl3 50933 Q9JKB1

Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) Proteine (Uchl3) nach Spezies

Weitere Proteine zu Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) Interaktionspartnern

Human Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3) Interaktionspartner

  1. Study demonstrated positive correlations between the level and activity of UCHL3 and sperm characteristics and function suggesting that UCHL3 may play a role in male infertility.

  2. Using a series of engineered protein substrates, which are similar in size yet differ in secondary structure, we demonstrate that thermal stability is a key factor that significantly affects UCH-L3 hydrolysis.

  3. UCH-L3 is a novel regulator of epithelial-mesenchymal transition and cell migration in prostate cancer cells.

  4. Data identified of UCHL3 as an essential deubiquitinase in adipogenesis.

  5. impaired UCH-L3 function may contribute to the accumulation of full length UBB (zeige UBB Proteine)(+1) in various pathologie

  6. 1.45 A resolution crystal structure of human UCH-L3 in complex with the inhibitor ubiquitin vinylmethylester, an inhibitor that forms a covalent adduct with the active site cysteine of ubiquitin-specific proteases

  7. Upregulation of UCH-L3 is associated with Uterine Cervical Neoplasms

  8. Substrate filtering by the active site crossover loop in UCHL3 revealed by sortagging and gain-of-function mutations.

  9. These results indicate that mono-Ub and Ub dimers may regulate the enzymatic functions of UCH-L1 (zeige UCHL1 Proteine) and UCH-L3, respectively, in vivo.

  10. Untangling the folding mechanism of the 5(2)-knotted protein UCH-L3

Mouse (Murine) Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3) Interaktionspartner

  1. Data suggest that the activity of oocyte UCHL-1 (zeige UCHL1 Proteine) and -3 contributes to oocyte maturation by regulating the oocyte cortex and meiotic spindle.

  2. subfertile Uchl1(gad-/-) mutant mice showed an intriguing pattern of switched UCH localization, with UCHL3 replacing UCHL1 (zeige UCHL1 Proteine) in the oocyte cortex

  3. impaired UCH-L3 function may contribute to the accumulation of full length UBB (zeige UBA52 Proteine)(+1) in various pathologie

  4. Results suggest that Uch-L3 enhances osteoblast differentiation through the stabilization of Smad1 (zeige SMAD1 Proteine) signaling

  5. Polyubiquitinated proteins accumulate in skeletal muscle as well as in mouse embryonic fibroblasts derived from Uchl3-deficient mice.

  6. Results suggest that UCH-L3 promotes adipogenesis by enhancing insulin (zeige INS Proteine) signaling in a hydrolase activity-dependent manner.

  7. The role of ubiquitin C-terminal hydrolase (zeige UCHL1 Proteine) (UCH)-L3 in the regulation of AMP-activated protein kinase (zeige PRKAA2 Proteine) activity and whole-body energy metabolism are reportedl

  8. UCH-L3 regulates the apical membrane recycling of the epithelial sodium channel

  9. Data show that Uchl3 and mitofilin are differentially expressed in the hippocampi of inbred senescence-acclerated mice compared to normally-aging mice.

Pig (Porcine) Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3) Interaktionspartner

  1. swine UCHL3, RIT1 (zeige RIT1 Proteine) and CCND3 (zeige CCND3 Proteine) genes were differentially expressed in tissues including small intestine, large intestine, liver, muscle, fat, lung, spleen and kidney

Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Alternative names and synonyms associated with Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3)

  • ubiquitin carboxyl-terminal esterase L3, pseudogene 1 (Uchl3-ps1)
  • ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (uchl3)
  • ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (UCHL3)
  • ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (Uchl3)
  • im:6908825 Protein
  • RGD1561196 Protein
  • UCH-6 Protein
  • UCH-L3 Protein
  • Uchl3 Protein
  • uchl4 Protein
  • zgc:109963 Protein

Bezeichner auf Proteinebene für Uchl3

ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) , ubiquitin carboxyl-terminal esterase L4 , ubiquitin carboxyl-terminal hydrolase isozyme L3 , ubiquitin thioesterase L3 , ubiquitin thiolesterase , UCH-L3 , ubiquitin carboxyl-terminal hydrolase-6

GENE ID SPEZIES
114094 Rattus norvegicus
549874 Xenopus (Silurana) tropicalis
7347 Homo sapiens
50933 Mus musculus
498560 Rattus norvegicus
554104 Danio rerio
495025 Xenopus laevis
395626 Gallus gallus
476947 Canis lupus familiaris
768115 Sus scrofa
520170 Bos taurus
Ausgewählte Anbieter für Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) Proteine (Uchl3)
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