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Thioesterase Superfamily Member 4 Proteine (THEM4)

Bezeichnung:
Thioesterase Superfamily Member 4 Proteine (THEM4)
Auf www.antikoerper-online.de finden Sie aktuell 6 Thioesterase Superfamily Member 4 (THEM4) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Thioesterase Superfamily Member 4 Antikörper (23) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 32 Thioesterase Superfamily Member 4 Produkte verfügbar.
Synonyme:
2700077M13Rik, 4921507I02Rik, CTMP, RGD1304723, THEM4
alle Proteine anzeigen Gen GeneID UniProt
THEM4 117145 Q5T1C6
THEM4 75778 Q3UUI3
Ratte THEM4 THEM4 361992 Q566R0

Weitere Synonyme anzeigen

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Weitere Proteine zu Thioesterase Superfamily Member 4 Interaktionspartnern

Human Thioesterase Superfamily Member 4 (THEM4) Interaktionspartner

  1. Suggest that CTMP may therefore play a critical role in mitochondrial-mediated apoptosis in lung cancer cells.

  2. Data show low or moderate methylation was found in seven selected genes BAD, BBC3 (zeige BBC3 Proteine), CAV1 (zeige CAV1 Proteine), CDK2AP1 (zeige CDK2AP1 Proteine), NPM1 (zeige NPM1 Proteine), PRKCDBP (zeige PRKCDBP Proteine) and THEM4.

  3. CTMP induces translocation of Akt (zeige AKT1 Proteine) to the membrane and thereby increases the level of Akt (zeige AKT1 Proteine) phosphorylation. As a result, CTMP enhances various cellular activities that are principally mediated by the PI3-kinase (zeige PIK3CA Proteine)/Akt (zeige AKT1 Proteine) pathway.

  4. Proper maturation of CTMP is essential for its pro-apoptotic function. CTMP delays PKB (zeige AKT1 Proteine) phosphorylation following cell death induction, suggesting that CTMP regulates apoptosis via inhibition of PKB (zeige AKT1 Proteine).

  5. Phosphorylation on Ser37/Ser38 of CTMP is important for the prevention of mitochondrial localization of CTMP, eventually leading to cell death by binding to heat shock protein 70 (zeige HSP70 Proteine).

Mouse (Murine) Thioesterase Superfamily Member 4 (THEM4) Interaktionspartner

  1. Results suggest that Akt (zeige AKT1 Proteine) is phosphorylated and translocated to nucleus after traumatic brain injury (TBI (zeige TBPL1 Proteine)) to exert neuroprotective effects; however, CTMP is simultaneously triggered to inhibit the phosphorylation of Akt (zeige AKT1 Proteine)

Thioesterase Superfamily Member 4 (THEM4) Protein Überblick

Protein Überblick

Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.

Alternative names and synonyms associated with Thioesterase Superfamily Member 4 (THEM4)

  • thioesterase superfamily member 4 (THEM4)
  • zgc:158847 (zgc:158847)
  • thioesterase superfamily member 4 (LOC100339997)
  • thioesterase superfamily member 4 (Them4)
  • Thioesterase superfamily member 4 (them4)
  • 2700077M13Rik Protein
  • 4921507I02Rik Protein
  • CTMP Protein
  • RGD1304723 Protein
  • THEM4 Protein

Bezeichner auf Proteinebene für THEM4

thioesterase superfamily member 4 , acyl-coenzyme A thioesterase THEM4 , C-terminal modulator protein , acyl-CoA thioesterase THEM4 , carboxyl-terminal modulator protein

GENE ID SPEZIES
457305 Pan troglodytes
609163 Canis lupus familiaris
791152 Danio rerio
100339997 Oryctolagus cuniculus
117145 Homo sapiens
75778 Mus musculus
361992 Rattus norvegicus
787270 Bos taurus
443715 Xenopus laevis
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