Spleen tyrosine Kinase Proteine (SYK)

Auf www.antikoerper-online.de finden Sie aktuell 16 Spleen tyrosine Kinase (SYK) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Spleen tyrosine Kinase Antikörper (380) und Spleen tyrosine Kinase Kits (49) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 468 Spleen tyrosine Kinase Produkte verfügbar.
Synonyme:
p72-Syk, p72syk, Sykb
alle Proteine anzeigen Gen GeneID UniProt
SYK 6850 P43405
SYK 20963 P48025
SYK 25155 Q64725

Spleen tyrosine Kinase Proteine (SYK) nach Spezies

Weitere Proteine zu Spleen tyrosine Kinase Interaktionspartnern

Human Spleen tyrosine Kinase (SYK) Interaktionspartner

  1. study demonstrates that high SYK expression is a common feature of CD21 (zeige CR2 Proteine)(low) B cells independent of the underlying disorder, and that this high expression is sufficient to drive constitutive phosphorylation of SYK and its immediate targets Bruton's tyrosine kinase (zeige BTK Proteine) and phospholipase Cgamma2

  2. IgG (mAb)-opsonized, inactivated Francisella tularensis LVS enhances macrophage and dendritic cell IL-1beta (zeige IL1B Proteine) responses in a TLR2- and FcgammaR-dependent fashion. FcgammaR-mediated Syk activation leads to NLRP3 (zeige NLRP3 Proteine) inflammasome-dependent IL-1beta (zeige IL1B Proteine) production in macrophages.

  3. High SYK expression is associated with lymphangioleiomyomatosis.

  4. NKp65 (zeige KLRF2 Proteine) utilizes a hemi-immunoreceptor tyrosine-based activation motif -like motif for cellular activation that requires Syk, although Syk appears not to be recruited to NKp65 (zeige KLRF2 Proteine).

  5. Syk is a key regulator of Hoxa9 (zeige HOXA9 Proteine)/Meis1 (zeige MEIS1 Proteine)-driven acute myeloid leukemia (zeige BCL11A Proteine).

  6. Data show that spleen tyrosine kinase (SYK) and proto-oncogene (zeige RAB1A Proteine) protein c-akt (AKT1 (zeige AKT1 Proteine)) proteins were increased in the cytoplasm of the cells forming Mallory-Denk bodies.

  7. B cell receptor signaling component, SYK, caused PAX5 (zeige PAX5 Proteine) tyrosine phosphorylation in vitro and in cells. Transcriptional repression on the BLIMP1 (zeige PRDM1 Proteine) promoter by PAX5 (zeige PAX5 Proteine) was attenuated by this phosphorylation.

  8. Pharmacological inhibitors of SYK activity significantly reduced the engulfment of oxLDL microbeads in the presence of serum factors, but had little effect on IgG phagocytosis.

  9. our data strongly suggest that AQCA-mediated suppression of inflammatory responses could be managed by a direct interference of signaling cascades including IRAK (zeige IRAK1 Proteine) and Syk, linked to the activation of NF-kappaB (zeige NFKB1 Proteine) and AP-1 (zeige FOSB Proteine).

  10. a potential link between the upregulation of Syk and VEGF-C (zeige VEGFC Proteine) expression and lung adenocarcinoma.

Mouse (Murine) Spleen tyrosine Kinase (SYK) Interaktionspartner

  1. ephrin B3 (zeige EFNB3 Proteine)/EphB2 (zeige EPHB2 Proteine) are obvious candidates for driving the Syk-dependent repulsive response.

  2. IgG (mAb)-opsonized, inactivated Francisella tularensis LVS enhances macrophage and dendritic cell IL-1beta (zeige IL1B Proteine) responses in a TLR2- and FcgammaR-dependent fashion. FcgammaR-mediated Syk activation leads to NLRP3 (zeige NLRP3 Proteine) inflammasome-dependent IL-1beta (zeige IL1B Proteine) production in macrophages.

  3. The effect of Smad4 (zeige SMAD4 Proteine) was at least partially mediated by the downstream effectors Syk and ROCK2 (zeige ROCK2 Proteine) transcription in megakaryocytes.

  4. Gene expression analysis of lung tissues revealed that HDM (zeige HDAC3 Proteine)-induced expression of IL-17 (zeige IL17A Proteine) and CXCL-1 (zeige CXCL1 Proteine) was significantly attenuated in both Sykdel/del and GSK143-treated mice. CONCLUSION: Syk inhibitors may play a role in the management of neutrophilic asthma

  5. collagen-I-mediated inhibition of proplatelet formation is specifically controlled by GPVI (zeige GP6 Proteine).

  6. Pharmacological Syk inhibition might provide a safe therapeutic strategy to prevent arterial thrombosis and to limit infarct progression in acute stroke.

  7. Studies indicate that SHP1 (zeige PTPN6 Proteine) and SYK crosstalk as a critical regulator of MyD88 (zeige MYD88 Proteine) post-translational modifications and IL-1 (zeige IL1A Proteine)-driven inflammation.

  8. dephosphorylation of Tyr (zeige TYR Proteine)(P)(346) may be considered an important "checkpoint" in the regulation of Syk activation process. Putative biological functions of TULA-2 (zeige STS1 Proteine)-mediated dephosphorylation of Tyr (zeige TYR Proteine)(P)(346) may include deactivation of receptor-activated Syk or suppression of Syk activation by suboptimal stimulation.

  9. These studies define a pathologic role for myeloid Syk signaling in renal ischemia/reperfusion injury

  10. Torreya nucifera butanol fraction exhibits anti-inflammatory activities by direct inhibition of macrophage Src (zeige SRC Proteine)/Syk/NF-kappaB (zeige NFKB1 Proteine) and IRAK1 (zeige IRAK1 Proteine)/AP-1 (zeige JUN Proteine) signaling.

Cow (Bovine) Spleen tyrosine Kinase (SYK) Interaktionspartner

  1. These data suggest that Syk mRNA expression dynamics is closely related to bovine leukemia virus-induced disease.

Spleen tyrosine Kinase (SYK) Protein Überblick

Protein Überblick

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Spleen tyrosine Kinase (SYK)

  • Tyrosine-protein kinase SYK (ksyk)
  • spleen tyrosine kinase (SYK)
  • spleen tyrosine kinase (Syk)
  • p72-Syk Protein
  • p72syk Protein
  • Sykb Protein

Bezeichner auf Proteinebene für Spleen tyrosine Kinase Proteine (SYK)

Tyrosine-protein kinase SYK , tyrosine-protein kinase SYK , protein-tyrosine kinase

GENE ID SPEZIES
100380388 Salmo salar
6850 Homo sapiens
20963 Mus musculus
25155 Rattus norvegicus
484196 Canis lupus familiaris
100125540 Sus scrofa
515515 Bos taurus
427272 Gallus gallus
100716985 Cavia porcellus
100345556 Oryctolagus cuniculus
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